1 ‐cyclohexyl‐x‐methoxybenzene derivatives, novel psychoactive substances seized on the internet market. Synthesis and in vivo pharmacological studies in mice

ConclusionsFor the first time, this study demonstrates that systemic administration of 1‐cyclohexyl‐x‐methoxybenzene compounds markedly inhibit visual response, promote analgesia, and induce core temperature alterations in mice. This data, although obtained in animal model, suggest their possible hazard for human health (i.e., hyperthermia and sensorimotor alterations). In particular, these novel psychoactive substances may have a negative impact in many daily activities, greatly increasing the risk factors for workplace accidents and traffic injuries.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Fhup.2560

Source: Human Psychopharmacology: Clinical and Experimental - June 28, 2017 Category: Psychiatry Authors: Anna Fantinati, Andrea Ossato, Sara Bianco, Isabella Canazza, Fabio De Giorgio, Claudio Trapella, Matteo Marti Tags: SPECIAL ISSUE ON NOVEL PSYCHOACTIVE SUBSTANCES Source Type: research