Significant elevations of serum lipase not caused by pancreatitis: a systematic review
ConclusionsA series of differential diagnoses for significant serum lipase elevations (i.e. exceeding three times the ULN) has been provided by this study. Clinicians should utilize this knowledge in the interpretation and management of patients who have lipase levels over three times as high as the ULN, remaining vigilant for an alternative diagnosis to pancreatitis. The medical officer should be aware of the possibility of incorrect diagnosis in the asymptomatic patient. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - June 2, 2014 Category: Gastroenterology Authors: Ahmer M. Hameed, Vincent W. T. Lam, Henry C. Pleass Tags: Review Article Source Type: research

Defining the post‐operative morbidity index for distal pancreatectomy
This study utilizes PMI to establish the complication burden for a distal pancreatectomy (DP). MethodsFrom 2005–2011, nine centres contributed ACS‐NSQIP complication data for 655 DPs. Each complication was assigned an Accordion severity weight ranging from 0.11 for grade 1 to 1.00 for grade 6 (death). The PMI is the sum of complication severity weights divided by the total number of patients. ResultsACS‐NSQIP complications occurred in 177 patients (27.0%). The non risk‐adjusted PMI for DP is 0.087. Bleeding/Transfusion and Organ Space Infection were the most common complications. Frequency and burden differed acros...
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - June 1, 2014 Category: Gastroenterology Authors: Major K. Lee, Russell S. Lewis, Steven M. Strasberg, Bruce L. Hall, John D. Allendorf, Joal D. Beane, Stephen W. Behrman, Mark P. Callery, John D. Christein, Jeffrey A. Drebin, Irene Epelboym, Jin He, Henry A. Pitt, Emily Winslow, Christopher Wolfgang, Ch Tags: Original Article Source Type: research

Patient selection and the volume effect in pancreatic surgery: unequal benefits?
DiscussionIn spite of a shift to high‐volume hospitals, a substantial cohort still receives a resection outside of these centres. Patients receiving non‐high‐volume care demonstrate less favourable comorbidities, insurance and urgency of operation. The implications are twofold: already disadvantaged patients may not benefit from the high‐volume effect; and patients predisposed to do well may contribute to observed superior outcomes at high‐volume centres. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - June 1, 2014 Category: Gastroenterology Authors: Lindsay A. Bliss, Catherine J. Yang, Zeling Chau, Sing Chau Ng, David W. McFadden, Tara S. Kent, A. James Moser, Mark P. Callery, Jennifer F. Tseng Tags: Original Article Source Type: research

Impact of pre‐operative positron emission tomography in gallbladder cancer
ConclusionAddition of PET to conventional cross‐sectional imaging has a modest impact on management pre‐operatively particularly in patients without a prior cholecystectomy and to confirm suspicious nodal disease on CT. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - June 1, 2014 Category: Gastroenterology Authors: Universe Leung, Neeta Pandit‐Taskar, Carlos U. Corvera, Michael I. D'Angelica, Peter J. Allen, T Peter Kingham, Ronald P. DeMatteo, William R. Jarnagin, Yuman Fong Tags: Original Article Source Type: research

Pancreaticogastrostomy is associated with significantly less pancreatic fistula than pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: a meta‐analysis of seven randomized controlled trials
ConclusionsPancreaticogastrostomy provides benefits over PJ after PD, including in the incidences of pancreatic fistula, biliary fistula and intra‐abdominal fluid collection and in hospital LoS. Therefore, PG is recommended as a safer and more reasonable alternative to PJ reconstruction after PD. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - June 1, 2014 Category: Gastroenterology Authors: Fu‐Bao Liu, Jiang‐Ming Chen, Wei Geng, Sheng‐Xue Xie, Yi‐Jun Zhao, Li‐Quan Yu, Xiao‐Ping Geng Tags: Review Article Source Type: research