Prophylactic octreotide in pancreatoduodenectomy: response to Yang et al.
(Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - January 27, 2015 Category: Gastroenterology Authors: Matthew T. McMillan, Charles M. Vollmer Tags: Letter to the Editor Source Type: research

Long‐term outcome after early repair of iatrogenic bile duct injury. A national Danish multicentre study
ConclusionIn this national, unselected and consecutive cohort of patients with BDI repaired by early HJ we found a considerable risk of long‐term complications (e.g. 30% stricture rate) and mortality in both the short‐ and the long‐term perspective. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - January 13, 2015 Category: Gastroenterology Authors: Nicolaj M. Stilling, Claus Fristrup, André Wettergren, Arnas Ugianskis, Jacob Nygaard, Kathrine Holte, Linda Bardram, Mogens Sall, Michael B. Mortensen Tags: Original Article Source Type: research

Does inchinkoto, a herbal medicine, have hepatoprotective effects in major hepatectomy? A prospective randomized study
ConclusionsThe preoperative administration of inchinkoto did not have a significant impact on the overall outcome of major hepatectomy. However, inchinkoto induced the expression of Nrf2 during hepatectomy and may have exerted an antioxidative effect on the liver. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - January 12, 2015 Category: Gastroenterology Authors: Tetsushi Mizutani, Yukihiro Yokoyama, Toshio Kokuryo, Tomoki Ebata, Tsuyoshi Igami, Gen Sugawara, Masato Nagino Tags: Original Article Source Type: research

Multimodal treatment of unresectable hepatocellular carcinoma to achieve complete response results in improved survival
DiscussionThis retrospective review of patients treated for intermediate and advanced stage HCC revealed a significant survival advantage in patients who achieved a complete response. These data support use of a multi‐modality approach to intermediate and advanced stage HCC, combining liver‐directed treatments as necessary to achieve a complete response. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - January 12, 2015 Category: Gastroenterology Authors: Pippa H. Newell, YingXing Wu, Helena Hoen, Richa Uppal, John Tyler Thiesing, Kevin Sasadeusz, Maria A. Cassera, Ronald F. Wolf, Paul Hansen, Chet W Hammill Tags: Original Article Source Type: research

Bile duct thrombi in hepatocellular carcinoma: is aggressive surgery worthwhile?
ConclusionThe mere presence of BDTT in HCC does not indicate an advanced or inoperable lesion. When technically feasible, a formal hepatic resection is the preferred first‐line treatment option in these patients. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - January 9, 2015 Category: Gastroenterology Authors: Ashwin Rammohan, Jeswanth Sathyanesan, Kamalakannan Rajendran, Anbalagan Pitchaimuthu, Senthil K. Perumal, Kesavan Balaraman, Ravi Ramasamy, Ravichandran Palaniappan, Manoharan Govindan Tags: Original Article Source Type: research

Conference Calendar
(Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - January 8, 2015 Category: Gastroenterology Tags: Conference Calendar Source Type: research

Highlights in this issue
(Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - January 8, 2015 Category: Gastroenterology Authors: Mark Callery, Saxon Connor, Stephen J. Wigmore Tags: Highlights in this issue Source Type: research

Intraoperative simulation of remnant liver function during anatomic liver resection with indocyanine green clearance (LiMON) measurements
ConclusionsIntraoperative ICG clearance measurements allow real‐time monitoring of intraoperative liver function during surgery. Trial clamping of arterial and portovenous inflow accurately predicts immediate post‐resection liver function. The intraoperative measurement of liver function and simulation of post‐resection liver function may help to avoid PHLF. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - January 1, 2015 Category: Gastroenterology Authors: Michael N. Thomas, Ernst Weninger, Martin Angele, Florian Bösch, Sebastian Pratschke, Joachim Andrassy, Markus Rentsch, Manfred Stangl, Werner Hartwig, Jens Werner, Markus Guba Tags: Original Article Source Type: research

Results of laparoscopic radiofrequency ablation for HCC. Could the location of the tumour influence a complete response to treatment? A single European centre experience
ConclusionLRFA of HCC is safe, feasible and achieves excellent results in selected patients. LRFA should be the first‐line technique for subcapsular lesions as it minimizes the risk of tumoural seeding and improves ICR. Proximity to gallbladder interferes in treatment efficacy (lower rate of ICR and lower rate of SCR). (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - December 29, 2014 Category: Gastroenterology Authors: Sofía Serna, Ramón Vilana, Santiago Sánchez‐Cabús, David Calatayud, Joana Ferrer, Victor Molina, Constantino Fondevila, Jordi Bruix, Josep Fuster, Juan‐Carlos García‐Valdecasas Tags: Original Article Source Type: research

Estimating the need for hepato‐pancreatico‐biliary surgeons in the USA
ConclusionsThe majority of the USA is underserved in terms of HPB surgery. Given the growing number of HPB‐trained physicians entering the job market, this sector should focus on bringing understanding and management of complex disease to areas of the country that are currently in need. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - December 29, 2014 Category: Gastroenterology Authors: Noaman Ali, Colin O'Rourke, Kevin El‐Hayek, Sricharan Chalikonda, D. Rohan Jeyarajah, R. Matthew Walsh Tags: Original Article Source Type: research

A qualitative study of patient and clinician attitudes regarding surveillance after a resection of pancreatic and peri‐ampullary cancer
DiscussionPatients have an intense need for reassurance and obtain this through follow‐up appointments with their oncologists. Consequently, they express few difficulties with the process. Clinicians recognize this desire for reassurance. Patients' understanding and expectations contrast starkly with clinicians' perspectives regarding prognosis. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - December 25, 2014 Category: Gastroenterology Authors: Raymond G. Deobald, Eva S. W. Cheng, Yoo‐Joung Ko, Frances C. Wright, Paul J. Karanicolas Tags: Original Article Source Type: research

Automated pancreatic cyst screening using natural language processing: a new tool in the early detection of pancreatic cancer
ConclusionNLP is an effective tool to automatically identify patients with pancreatic cysts based on electronic medical records (EMR). This highly accurate system can help capture patients ‘at‐risk’ of pancreatic cancer in a registry. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - December 24, 2014 Category: Gastroenterology Authors: Alexandra M. Roch, Saeed Mehrabi, Anand Krishnan, Heidi E. Schmidt, Joseph Kesterson, Chris Beesley, Paul R. Dexter, Mathew Palakal, C. Max Schmidt Tags: Original Article Source Type: research

Assessment of the external validity of a predictive score for blood transfusion in liver surgery
ConclusionsIn the present population, the TRS appeared to serve as a weak predictor of perioperative transfusion. This study confirms that the external validity of the transfusion predictive score should be subject to further investigation before it can be implemented in clinical use. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - December 17, 2014 Category: Gastroenterology Authors: Sylvie Janny, Mathilde Eurin, Safi Dokmak, Amélie Toussaint, Olivier Farges, Catherine Paugam‐Burtz Tags: Original Article Source Type: research

Are sarcopenia, obesity and sarcopenic obesity predictive of outcome in patients with colorectal liver metastases?
ConclusionSarcopenia, obesity and sarcopenic obesity did not worsen DFS, OS and complication rates after a partial liver resection for CRLM. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - December 16, 2014 Category: Gastroenterology Authors: Toine M. Lodewick, Thiemo J. A. Nijnatten, Ronald M. Dam, Kim Mierlo, Simon A. W. G. Dello, Ulf P. Neumann, Steven W. M. Olde Damink, Cornelis H. C. Dejong Tags: Original Article Source Type: research

Identification of risk categories for in pancreaticoduodenectomy based on diagnosis
ConclusionsThe high‐risk diagnosis is independently associated with postoperative morbidity and prolonged LoS. Patients with PD should be stratified by diagnosis to more accurately reflect their risk for postoperative complications and the complexity of care they will require. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - December 16, 2014 Category: Gastroenterology Authors: Christopher R. Shubert, Michael L. Kendrick, Kristine M. Thomsen, Michael B. Farnell, Elizabeth B. Habermann Tags: Original Article Source Type: research