The facial nerve versus the retromandibular vein: a new anatomical relationship.
The facial nerve is an important nerve that handles different functions. Its relation to the retromandibular vein and parotid tumors should be estimated preoperatively to avoid nerve injury or bleeding that might result from different unexpected nerve-vein relationship. We have reported a new case of 65-year-old male with right Warthin tumor who underwent superficial parotidectomy that showed a new facial nerve and retromandibular vein relationship. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Treatment and prognosis of patients with recurrent laryngeal carcinoma: a retrospective study.
Conclusion
Our result suggests that lower initial T stage, no initial cervical lymph node metastasis, only localrecurrence and patients suitable for salvage surgeryare favorable prognostic factors for overall survival of patients with recurrent laryngeal cancer. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Prognostic significance of pre-treatment latent membrane protein 1 from nasopharyngeal swabs for stage III-IVA nasopharyngeal carcinoma.
Conclusion:Pre-treatment LMP1 as detected by nasopharyngeal swabs using PCR is an adverse prognostic factor for Stage III-IVA NPC, and potentially can be used as a treatment stratification tool. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Surgical extent impacts the value of the established prognosticators in glioblastoma patients: a prospective translational study in Asia.
Conclusion:Surgical extent most significantly impacts the value ofmolecular and clinical predictors, and therefore should be takeninto full account when assessing a new therapyor stratification variablein GBMs. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Management of the clinically negative neck (N0) of T2N0M0 supraglottic laryngeal carcinoma: A retrospective study.
Conclusion: Our result suggests that neck dissection is not superior to radiotherapy or a ‘wait and see’ policy in terms of survival and control of neck disease. A ‘wait and see’ policy may be the best choice for these patients. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Re-irradiation in Head & Neck cases using IMRT technique: a retrospective study with toxicity and survival report.
Conclusion: The IMRT technique allows the re-irradiation with safety and tolerated toxicity. However, future prospective studies of these approaches with much more patients are warranted. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
High hypoxia-inducible factor-1α expression genotype associated with Eastern Cooperative Oncology Group performance in head and neck squamous cell carcinoma.
Conclusions: In conclusion, our study demonstrated that the C1772T and polymorphism of the HIF-1α gene are associated with poor ECOG-PS. Our data suggests that the presence of the TT genotype in HNSCC individuals might contribute to the higher clinical aggressiveness of malignant disease. Such findings may have implications for interruptions in the disease process and modifications in treatment regiments. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Microscopic endo-nasal access in pituitary surgery for tumour removal: 8 year review of nasal complications.
Conclusion
Nasal complication rates from this method are low. The microscope can be successfully used in an endo-nasal approach to the sella on its own. It can also be a useful adjunct to the endoscope and this skill should not be forgotten by ENT and neurosurgeons. It appears the method of approaching the sella (trans- nasal versus trans-septal) rather than the instrument used that helps determine the rate of nasal complications. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Unusual metastases from papillary thyroid carcinoma.
Papillary thyroid carcinoma is the most common type of well-differentiatedthyroid carcinoma. Metastases usually occur in regional lymph nodes. Here,we report a patient with unusual metastases from papillary thyroidcarcinoma.A 55-year-old woman had a history of right papillary thyroid carcinoma and underwent local excision of the right thyroid lobe in another hospital previously. The patient was found to have metastatic papillary thyroid carcinoma to the left parietooccipital lobe, bilateral lung, the left caput humeri, the left triceps brachii muscle, the right collum ossis femoris and left thumb. She eventually suffered m...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
A new tool to inform intra-operative decision making in skin cancer treatment: the non-invasive assessment of basal cell carcinoma of the skin using elastic scattering spectroscopy.
Conclusions: This preliminary study shows that ESS can distinguish between basal cell cancer, common benign conditions and variants of normal skin. ESS can also help determine the diagnosis between benign lesions with a high degree of accuracy suggesting ESS can add significant objectivity to dermatological diagnosis and management even of benign conditions.
(Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
One-Stage Skin Grafting of the Exposed Skull with Artificial Dermis after cancer removal: Long-term Experiences.
Various surgical procedures claim to show high success rate in scalp reconstruction. However, it is still difficult to cover wide range of scalp defects accompanied with skull exposure after cancer removal. Between March 2007 and March 2010, one-stage skin grafting with artificial dermis was performed in 8 patients with scalp defect accompanied with skull exposure after malignancy resection. A burr hole was made with several millimeter gap to the skull’s outer table, and thus vascular diploic space was exposed. After the application of artificial dermis to the exposed vascular diploic space, the split-thickness skin ...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
The Deleterious nature of the invasive front and dysplasia at margin in the long term outcome from surgical treatment of squamous cell carcinoma of the head and neck.
Discussion
The nature of the invasive front should be considered in any prognostic discussion and when planning surgery. Transfusion triggers should be revised to avoid transfusion of blood products (which have cancer growth promoting properties). The survival rates after recurrence of disease is poor, in part due to the entrenched adaptive behaviors of the residual tumour cells which manifest several areas of resilience (i.e. radiotherapy, chemotherapy) and which may have already invaded local important structures (making them resilient to surgery ).
To improve the overall survival rates, we must addres...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Stomatin-like protein-2 is over-expressed during progression of clinically N0 tongue squamous cell cancer.
Stomatin-like protein 2 (SLP-2) contributes to tumorigenesis, progression and decreased overall survival in several human cancers. The present study investigated the clinical and prognostic significance of SLP-2 in clinically N0 tongue squamous cell cancer. Immunohistochemistry was performed to examine SLP-2 protein expression in paraffin-embedded tissues from 181 patients with clinically N0 tongue squamous cell cancer (cN0 TSCC). Statistical analyses were used to evaluate the diagnostic value and the associations of SLP-2 expression with clinical parameters. Real-time PCR and western blotting analyses were employed to exa...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Do patients with oral and oropharyngeal squamous cell carcinoma benefit from elective contralateral neck dissection? A long-term analysis.
Conclusion: We could not find a statistical benefit for operating on patients with oral and oropharyngeal SCC with an elective neck dissection on the contralateral clinical negative neck side. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Prediction of occult cervical lymph node metastasis in clinically negative supraglottic squamous cell carcinoma.
Conclusion: Cervical lymph node metastasis in clinically negative supraglottic SCCA results in lower 5-year OS rates. The histological differentiation and the treatment modality of surgery plus postoperative radiotherapy for the primary tumor site were found to be independent predictors for OCLNM-FS. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
