Lee JY, Jeong YJ, Ho Kwon, Jung SN. Extra-abdominal desmoid tumor presented as neck swelling in the trapezius muscle: a case report. Head Neck Oncol. 2012 Sep 9;4(2):53.
Desmoid tumor is a type of benign fibromatosis arising from musculoaponeurotic structures. It is clinicopathologically classified into two subtypes, intra-, and extra-abdominal, and is mainly developed in abdomen. Herein, this report is aimed to describe a rare case of desmoid tumor developed in the trapezius muscle presenting neck swelling. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Buda I, Bachar G, Gilam A, Modai S, Strenov Y, Pasmanik-Chor M, Feinmesser R, Shomron N. Differential expression of microRNAs between aggressive and non-aggressive papillary thyroid carcinoma. Head Neck Oncol. 2012 Sep 9;4(2):52.
Conclusion
In this work a set of microRNAs differentially expressed between aggressive versus non aggressive papillary carcinoma have been defined. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Zhou XC, Hu KQ, Zhang XF, Ye YH, Jiang Y, Pan F, Li XY, Zhou H. Breast cancer metastatic to the bilateral thyroid: a case report. Head Neck Oncol. 2012 Sep 9;4(2):51.
We describe the case of a 41-year-old woman with a history of bilateral breast cancer, presented with elevated serum carbohydrate antigen (CA) 153 level, and ultrasonography revealed the bilateral thyroid lobes and isthmus diffuse distribution of point-like calcifications, no nodules were palpable, total thyroidectomy was performed. A firm diagnosis of metastatic breast carcinoma to the thyroid was established. With this report, we should strengthen the argument that any patient with a thyroid lesion and a history of malignancy should be considered to have a metastasis until proven otherwise, also we conclude that total th...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Fujimaki M, Yokoyama J, Ohba S, Anzai T, Yoshii Y, Ito S, Kojima M, Ikeda K. Dynamic imaging in determining the optimum surgical time for NIR fluorescent image-guided surgery a preliminary study. Head Neck Oncol. 2012 Sep 9;4(2):50.
Conclusion
ICG fluorescence imaging is effective for the detection in vivo of head and neck cancer. Preliminary findings suggest that the optimum timing for surgery is from 3hrs to 24hrs after the ICG injection. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Lim TC, Chua MLK, Chia GS, Ng DCE, Ong SC, Wee JTS, Khoo JBK. Comparison of MRI, CT and 18F-FDG-PET/CT for the detection of intracranial disease extension in nasopharyngeal carcinoma. Head Neck Oncol. 2012 Sep 9;4(2):49.
CONCLUSION
MRI remains the modality of choice for detecting intracranial disease extension of NPC. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Park CY, Lee KE, Lim SJ, Kim HJ. Spontaneous regression of recurred adenoid cystic carcinoma in the nasal cavity. Head Neck Oncol. 2012 Sep 9;4(2):48.
Adenoid cystic carcinoma (ACC) is an epithelial tumor of the major and minor salivary glands, accounting for about 1% of all malignant tumors of the oral and maxillofacial region. Surgical excision with wide margins is the treatment of choice for ACC, but the tendency of this tumor to recur locally and to develop distant metastasis is correlated with an ultimately poor prognosis. Spontaneous remission (SR) of cancer, especially in the sinonasal tract, is a rare biological event. Here, we present a case of recurred ACC of the nasal cavity which regressed spontaneously after intranasal biopsy. We also present a brief review ...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Song X, Xia R, Cui Z, Chen W, Mao L. Presenilin 1 is frequently overexpressed and positively associates with EGFR expression in head and neck squamous cell carcinoma. Head Neck Oncol. 2012 Sep 9;4(2):47.
Conclusions
Our data indicated that PS1 is frequently overexpressed in HNSCC. In contrary to the previous reports, out data showed that PS1 is positively related to EGFR expression in HNSCC and suggested that PS1 may serve as an alternative target for inhibiting EGFR signaling in HNSCC. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Feng J, Tian L, Sun Y, Li D, Wu T, Wang Y, Liu M. Expression of long non-coding RNA MALAT-1 is correlated with progress and apoptosis of laryngeal squamous cell carcinoma. Head Neck Oncol. 2012 Sep 9;4(2):46.
CONCLUSION
Taken together, these data suggest an important role for MALAT-1 in the progress of LSCC and the potential application of MALAT-1 in LSCC therapy. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Bernardes VF, Gomes CC, Gomez RS. Molecular investigation of ameloblastic fibroma: how far have we gone? Head Neck Oncol. 2012 Sep 9;4(2):45.
The ameloblastic fibroma is an uncommon odontogenic tumour that may present an aggressive behaviour and potential for malignant transformation. Despite all the efforts to clarify the pathogenesis of odontogenic tumours, the origin of the ameloblastic fibroma is still uncertain. This review focuses on the molecular pathogenesis of the ameloblastic fibroma. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Schepers RH, Raghoebar GM, Lahoda LU, Van der Meer WJ, Roodenburg JL, Vissink A, Reintsema H, Witjes MJ. Full 3D digital planning of implant supported bridges in secondarily mandibular reconstruction with prefabricated fibula free flaps. Head Neck Oncol. 2012 Sep 9;4(2):44.
Conclusions
3D planning allowed for positioning of a fibula bone graft by means of an implant supported bridge which resulted in a functional position of the graft and bridge. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Upile T, Jerjes W, Mahil J, Hamdoon Z, Radhi H. Microendoscopy: a clinical reality in intra-operative margin analysis of head and neck lesions. Head Neck Oncol. 2012 Sep 9;4(2):43.
Conclusion
We have developed the use of the microendoscope to aid intra-operative decision making during surgery. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Upile T, Jerjes W, Sandison A, Sudhoff H, Wong BJ, Hopper C. The ABC of Head and Neck Oncology publishing ethics. Head Neck Oncol. 2012 Sep 9;4(2):42.
As medical editors we are faced with a host of ethical dilemmas upon a daily basis. Most are recognised and dealt with expediently but the few that remain must be challenged as a cohesive body of editorial opinion. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Wang K, Wang JH, Baskaran H, Wang R, Jurevic R. Effect of human beta-defensin-3 on head and neck cancer cell migration using micro-fabricated cell islands. Head Neck Oncol. 2012 Jun 28;4(1):41.
Conclusions
VEGF enhanced cancer cell migration. The combination of DMEM and VEGF showed a synergistic effect on this phenomenon of cancer cell migration. Conditioned medium with hBD-3 suppressed cancer cell migration. hBD-3 suppressed VEGF enhancement of TR146 cancer cell migration. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Nankivell PC, Dunn JA, Langman MJ, Mehanna H. Feasibility of recruitment to an oral dysplasia trial in the United Kingdom. Head Neck Oncol. 2012 Jun 25;4(1):40.
Conclusion
This feasibility trial has demonstrated the low incidence of OED in the UK and the difficulties in conducting a study because of this. With an incidence of around 1.5/100,000/year and a high proportion of those patients already taking or intolerant of Aspirin, a large multi-centred trial would be required to fulfil the recruitment for this study. The ability of topical non-steroidal anti-inflammatory drugs to modify COX and prostaglandin expression remains an important but unanswered question. Collaboration with centres in other parts of the world with higher incidences of the disease may be required to ensure...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Ramadan S, Ugas MA, Berwick R, Notay M, Cho H, Jerjes W, Giannoudis PV. Spinal metastasis in thyroid cancer. Head Neck Oncol. 2012 Jun 25;4(1):39.
Conclusions
The management of spinal metastasis from thyroid cancer should be multi-disciplinary. There is an absence; it seems, of a definitive protocol for treatment. Research shows increased survival with 131I avidity and complete bone metastasis resection. Early detection and treatment therefore are crucial. Studies suggest in those patients below the age of 45 years that treatment should be aggressive, and aim for cure. In those patients in whom curative treatment is not an option, palliative treatments are available. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
