Song X, Xia R, Cui Z, Chen W, Mao L. Presenilin 1 is frequently overexpressed and positively associates with EGFR expression in head and neck squamous cell carcinoma. Head Neck Oncol. 2012 Sep 9;4(2):47.

Conclusions Our data indicated that PS1 is frequently overexpressed in HNSCC. In contrary to the previous reports, out data showed that PS1 is positively related to EGFR expression in HNSCC and suggested that PS1 may serve as an alternative target for inhibiting EGFR signaling in HNSCC.
Source: Head and Neck Oncology - Category: Cancer & Oncology Source Type: research