Kakei Y, Akashi M, Komatsubara H, Minamikawa T, Komori T. p16 overexpression in malignant and premalignant lesions of the oral and esophageal mucosa following allogeneic hematopoietic stem cell transplantation. Head Neck Oncol. 2012 Jun 23;4(1):38.
Conclusions
Pathological examinations with p16 immunohistochemistry may contribute to an early diagnosis of secondary malignancy after HSCT. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Carbiner R, Jerjes W, Shakib K, Giannoudis PV, Hopper C. Analysis of the compatibility of dental implant systems in fibula free flap reconstruction. Head Neck Oncol. 2012 Jun 21;4(1):37.
This study reached a conclusion that the width of fibula is sufficient for placement of most frequently used dental implants for oral rehabilitation after mandibular reconstructive procedures. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Trilling GM, Cho H, Ugas MA, Saeed S, Katunda A, Jerjes W, Giannoudis PV. Spinal metastasis in head and neck cancer. Head Neck Oncol. 2012 Jun 20;4(1):36.
Conclusion
Management should aim to improve end-stage quality of life and maintain neurological function. This review has found that radiotherapy +/− medical adjuvant is considered the principle treatment of spinal metastasis of head and neck cancers.
There is an absence of a definitive treatment protocol for head and neck cancer spinal metastasis. Our failure to find and cite high-quality scientific evidence only serves to stress the need for good quality research in this area. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Kobayashi J, Miyazaki A, Yamamot T, Nakamori K, Suzuki R, Kaneko T, Suzuki N, Hiratsuka H. Granulocyte colony-stimulating factor-producing squamous cell carcinoma of the lower gingiva: a case report. Head Neck Oncol. 2012 Jun 19;4(1):35.
The present study summarizes our experience in treating a patient with a suspected granulocyte colony-stimulating factor (G-CSF)-producing squamous cell carcinoma (SCC) of the lower gingiva, which is a rather rare entity.
A 56-year-old woman underwent surgical excision of palate leukoplakia in 1996. In 2009, however, a leukoplakic superficial tumor was detected in the lower left gingiva, for which the patient underwent gingivectomy. This was subsequently diagnosed as SCC. The patient also underwent superselective arterial injection chemotherapy combined with radiotherapy, after local recurrence was observed. The patient ...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Pereira GG, Silva JC, Monteiro EF. Positron emission tomography in the detection of occult primary head and neck carcinoma: a retrospective study. Head Neck Oncol. 2012 Jun 18;4(1):34.
Conclusions
Therefore, PET is a valuable tool in the management of patients with occult primary head and neck carcinoma, not only because it provides additional information as to the location of primary tumors, but also due to the fact that it can detect unexpected distant metastases. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Upile T, Jerjes W, Abiola J, Kafas P, Sandison A, Hamdoon Z, Al-Khawalde M, Radhi H. A patient with primary Burkitt`s lymphoma of the postnasal space: case report. Head Neck Oncol. 2012 Jun 13;4(1):33.
Conclusion
This is the first reported case of sporadic Burkitt’s lymphoma of the postnasal space of an elderly Caucasian male in the absence of Epstein - Barr virus or human immunodeficiency virus infection and further serves to illustrate the diversity of histological subtypes of malignancies that may develop at this concealed site. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Ghazali N, Lowe D, Rogers SN. Enhanced patient reported outcome measurement suitable for head and neck cancer follow-up clinics. Head Neck Oncol. 2012 Jun 13;4(1):32.
Conclusions
The W-S-B question adds little questionnaire burden and could help to better identify patients who might benefit from intervention. The results of this study suggest that the UW-QOL with the W-S-B modification should be used together with the PCI to allow optimal identification of issues for patient-clinician discussion during routine outpatient clinics. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Upile T, Jerjes W, Al-Khawalde M, Radhi H. Oral sex, cancer and death: sexually transmitted cancers. Head Neck Oncol. 2012 Jun 6;4(1):31.
We briefly highlight the growing body of recent evidence linking unprotected oral sex with the development of some types of head and neck cancer in younger patients. These tumours appear to be increasing in incidence although the development of more sensitive methods of HPV detection may be a confounding factor. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Hamdoon Z, Jerjes W, Al-Delayme R, Hopper C. Solitary giant neurofibroma of the neck subjected to photodynamic therapy: case study. Head Neck Oncol. 2012 Jun 6;4(1):30.
Photodynamic therapy (PDT) - the fourth modality - has been successfully used in the management of early and advanced pathologies of the head and neck. We studied the effect of this modality on a giant solitary neurofibroma of the neck.
A 70-year-old Caucasian female presented with left neck pain and disfigurement associated with slight shortness of breath and dysphagia. Examination revealed a large mass in the neck with no neurovascular compromise. Magnetic resonance imaging (MRI) reported a heterogeneously enhancing mass extending from the left angle of the mandible to the base of the neck. A core biopsy was performed ...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Hamdoon Z, Jerjes W, Al-Delayme R, McKenzie G, Jay A, Hopper C. Structural validation of oral mucosal tissue using optical coherence tomography. Head Neck Oncol. 2012 Jun 6;4(1):29.
Conclusion
This study enabled the creation of OCT bank of normal and pathological oral tissues. The pathological changes identified using OCT enabled differentiation between normal and pathological tissues, and identification of different tissue pathologies.
Further studies are required to assess the accuracy of OCT in identification of various pathological processes involving the oral tissues. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Udeabor SE, Rana M, Wegener G, Gellrich NC, Eckardt AM. Squamous cell carcinoma of the oral cavity and the oropharynx in patients less than 40 years of age: a 20-year analysis. Head Neck Oncol. 2012 May 30;4(1):28.
Conclusion
The results from the present study showed that young adults may have a better prognosis especially in terms of long term overall survival from oral and oropharyngeal carcinoma. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Hafez MT, Hegazy MA, Abd Elwahab K, Arafa M, Abdou I, Refky B. Metastatic rhabdomyosarcoma of the thyroid gland, a case report. Head Neck Oncol. 2012 May 29;4(1):27.
We report a case of 22-years-old woman with right leg rhabdomyosarcoma metastatic to the thyroid gland. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Hu J, Bao YY, Cheng KJ, Zhou SH, Ruan LX, Zheng ZJ. Computed tomography and pathological findings of five nasal neurilemmomas. Head Neck Oncol. 2012 May 23;4(1):26.
Conclusions
Schwannoma should be considered in the differential of unusual nasal masses. Certain clinical and CT patterns may be of use in the differential diagnosis. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Upile T, Jerjes W, Sipaul F, Sandison A, Kafas P, Al-Khawalde M, Radhi H. A patient with ulcerated calcifying epithelioma of Malherbe in the pinna: case report. Head Neck Oncol. 2012 May 21;4(1):25.
Conclusion
A search of the world’s literature has led us to believe that this is a rare case of a calcifying epithelioma of Malherbe of the pinna. The rapid growth and ulcerative nature of this tumour makes this case even more unique. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Upile T, Jerjes W, Al-Khawalde M, Kafas P, Frampton S, Gray A, Addis B, Sandison A, Patel N, Sudhoff H, Radhi H. Branchial cysts within the parotid salivary gland. Head Neck Oncol. 2012 May 18;4(1):24.
Cystic lesions within the parotid gland are uncommon and clinically they are frequently misdiagnosed as tumours. Many theories have been proposed as to their embryological origin. A 20-year retrospective review was undertaken of all pathological codes (SNOMED) of all of patients presenting with any parotid lesions requiring surgery. After analysis seven subjects were found to have histopathologically proven parotid branchial cysts in the absence of HIV infection and those patients are the aim of this review. Four of the most common embryological theories are also discussed with regard to these cases, as are their managemen...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
