Tunio MA, Al Asiri M, Fagih M, Akasha R. Primary squamous cell carcinoma of thyroid: a case report and review of literature. Head Neck Oncol. 2012 Mar 27;4:8.
Conclusion
Primary SCC of thyroid is rare and aggressive entity. FNAC is reliable and effective tool for immediate diagnosis. Surgery is a curative option, but it is not always possible as most of cases present as locally advanced with adjacent organs involvement. EBRT alone was found ineffective. Aggressive combined modality (debulking surgery, radiation and chemotherapy) shall be considered for such cases. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Jia-Jun T, Su-Mei L, Liang Y, Ju-Ke M, Ya-Kui M, Hai-Bo W, Wei X. Nimesulide inhibited the growth of hypopharyngeal carcinoma cells via suppressing Survivin expression. Head Neck Oncol. 2012 Mar 27;4:7.
Conclusions
Based on the induction of apoptosis and suppression of proliferation, Nimesulide could inhibit the growth of FaDu cells. Furthermore, the suppression of Survivin expression may play an important role in Nimesulide-induced growth inhibition. Nimesulide could act as an effective therapeutic agent for hypopharyngeal carcinoma therapy. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Jerjes W, Upile T, Radhi H, Petrie A, Abiola J, Adams A, Kafas P, Callear J, Carbiner R, Rajaram K, Hopper C. The effect of tobacco and alcohol and their reduction/cessation on mortality in oral cancer patients: short communication. Head Neck Oncol. 2012 Mar 12;4:6.
Conclusion
Chronic smoking and drinking does have an adverse effect on patients with oral cancer leading to increased mortality from cancer-related causes. Reduction/cessation of these habits tends to significantly reduce mortality in this group of patients. Smoking and drinking cessation counseling should be provided to all newly diagnosed oral cancer patients. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
cTNM vs. pTNM: the effect of not applying ultrasonography in the identification of cervical nodal disease.
In this study, we compared clinical TNM (cTNM) staging (not including ultrasonography) to pathological TNM (pTNM) staging in 245 patients presenting with carcinoma of the oral cavity and the oro-pharyngeal region. Tumour size differences and nodal involvement were highlighted. US reports of the neck were then added to the clinical staging and results compared.
Tumour size was clinically underestimated in 4 T1, 2 T2 and 2 T3 oral diseases. Also 20 patients that were reported as nodal disease free had histological proven N1 or N2 nodal involvement; while 3 patients with cTNM showing N1 disease had histologically proven N2 ...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Luo YZ, Dai LB, Zhou SH, Luo XM, Fan J, Ruan LX. Etiology analysis and computed tomography imaging of a tonsillar inflammatory myofibroblastic tumor: report of an immunocompetent patient and brief review. Head Neck Oncol. 2012 Mar 9;4:4.
Conclusions
Tonsillar IMT may be a benign tumor. We suggest that preoperative recognition of tonsillar IMT by CT may be important to avoid unnecessary expanded surgery. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Gonçalves JJ, Rocha AM. A decision support system for quality of life in head and neck oncology patients. Head Neck Oncol. 2012 Feb 16;4:3.
Conclusions
The possibility of representing graphically useful results that physician needs to analyze in the appointment, immediately after the answer collection, in an useful time, makes this QoL assessment platform a diagnosis instrument ready to be used routinely in clinical practice. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Schiphorst AH, Twigt BA, Elias SG, van Dalen T. Randomized clinical trial of LigaSure versus conventional suture ligation in thyroid surgery. Head Neck Oncol. 2012 Jan 18;4:2.
Conclusion
Using an electrothermal vessel sealing system during thyroid surgery is time saving. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Saman DM. A review of the epidemiology of oral and pharyngeal carcinoma: update. Head Neck Oncol. 2012 Jan 13;4:1.
Oral and pharyngeal cancers are the sixth most common cancers internationally. In the United States, there are about 30,000 new cases of oral and pharyngeal cancers diagnosed each year. Furthermore, survival rates for oral and pharyngeal cancers have not significantly improved over the last three decades. This review examines the scientific literature surrounding the epidemiology of oral and pharyngeal cancers, including but not limited to risk factors, disparities, preventative factors, and the epidemiology in countries outside the United States. The literature review revealed that much of the research in this field has b...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Gerber S, Gengler C, Grätz KW, Kruse AL. The impact of frozen sections on final surgical margins in squamous cell carcinoma of the oral cavity and lips: a retrospective analysis over an 11 years period. Head Neck Oncol. 2011 Dec 30;3:56.
Conclusions
Our data suggests that intraoperative FS in SCC can be useful in selected cases. However it is not advisable as a routine approach. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Upile T, Jerjes W, Radhi H, Al-Khawalde M, Kafas P, Nouraei S, Sudhoff H. Vascular mimicry in cultured head and neck tumour cell lines. Head Neck Oncol. 2011 Dec 23;3:55.
We present experimental evidence of vasculogenic mimicry in HNSCC cell lines and compare them with other tumours and a positive control vascular cell line.
Materials and methods
The cell lines used were HUVEC, HN 2a, 2b (primary and metastatic tongue base squamous carcinoma cell line), HCT116 (colonic carcinoma cell line) and DU145 (prostate carcinoma cell line).
Pilot experiments were undertaken to assess growth of a bank of tumour cell lines on (growth factor reduced) matrigel (Sigma) with standard media (DMEM with 10% Fetal Calf Serum).
A functional growth assay was performed by preparing the appropriate cell su...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Upile T, Jerjes W, Mahil J, Tailor H, Balakumar R, Rao A, Qureshi Y, Bowman I, Mukhopadhyay S. How to do it: the difficult thyroid. Head Neck Oncol. 2011 Dec 23;3:54.
We describe our approach to the difficult thyroid. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Jerjes W, Upile T, Radhi H, Hopper C. Photodynamic therapy vs. photochemical internalization: the surgical margin. Head Neck Oncol. 2011 Dec 22;3:53.
Controlling tumour margins in head and neck surgery is of the utmost importance in preventing loco-regional spread and distant metastasis, which will ultimately lead to a significant reduction in morbidity and mortality. We comment on the surgical margins in photodynamic therapy and photochemical internalization. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
English law for the surgeon II: clinical negligence.
Traditionally, in the United Kingdom and Europe, the surgeon was generally not troubled by litigation from patients presenting as elective as well as emergency cases, but this aspect of custom has changed. Litigation by patients now significantly affects surgical practice and vicarious liability often affects hospitals. We discuss some fundamental legal definitions, a must to know for a surgeon, and highlight some interesting cases. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Amin AA, Sakkary MA, Khalil AA, Rifaat MA, Zayed SB. The submental flap for oral cavity reconstruction: extended indications and technical refinements. Head Neck Oncol. 2011 Dec 20;3:51.
Conclusion
The submental flap is a valid option for reconstruction of intra-oral soft tissue as well as composite oral defects particularly in elderly patients. However, oncologically sound neck dissection should be assured. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Ono S, Rana M, Takechi M, Ogawa I, Okui G, Mitani Y, Gellrich NC, Kamata N. Myxolipoma in the tongue - a clinical case report and review of the literature. Head Neck Oncol. 2011 Dec 20;3:50.
In this article, we present our experience with a case of myxolipoma of the tongue.
Lipoma is a mesenchymal benign tumor occurring with relatively high frequency. However, myxolipoma, one of the histological variant of lipoma characterized by mature adipose tissue and abundant mucoid substances, in the oral cavity is quite rare.
The patient was a 52-year-old man who noticed a painless mass on the left border of tongue about 2 years ago. The lesion was noted at a complete medical checkup, and the patient was admitted to our institution for detailed examination. The mass was a palpable, soft and elastic nodule, 15 mm in ...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
