Jia-Jun T, Su-Mei L, Liang Y, Ju-Ke M, Ya-Kui M, Hai-Bo W, Wei X. Nimesulide inhibited the growth of hypopharyngeal carcinoma cells via suppressing Survivin expression. Head Neck Oncol. 2012 Mar 27;4:7.

Conclusions Based on the induction of apoptosis and suppression of proliferation, Nimesulide could inhibit the growth of FaDu cells. Furthermore, the suppression of Survivin expression may play an important role in Nimesulide-induced growth inhibition. Nimesulide could act as an effective therapeutic agent for hypopharyngeal carcinoma therapy.
Source: Head and Neck Oncology - Category: Cancer & Oncology Source Type: research