Reactive oxygen species, ageing and the hormesis police
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - August 23, 2013 Category: Research Authors: Paula Ludovico, William C. Burhans Tags: MiniReview Source Type: research
Using yeast to uncover the regulation of protein kinase Cδ by ceramide
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - August 20, 2013 Category: Research Authors: Cláudia Bessa, Clara Pereira, Mariana Leão, Cláudia Maciel, Sara Gomes, Jorge Gonçalves, Manuela Corte‐Real, Vítor Costa, Lucília Saraiva Tags: Research Paper Source Type: research
Synthetically prepared glycooligosaccharides mimicking Candida albicans cell wall glycan antigens – novel tools to study host–pathogen interactions
Abstract
The immunobiological efficacy of synthetically prepared mannooligosaccharides and a glucooligosaccharide mimicking the structure of Candida albicans cell wall glycans was assessed in vivo and in vitro to exploit immune responses. The exposure of mice splenocytes to BSA‐based conjugates of synthetic oligomannosides and oligoglucoside revealed intense influence on T‐cell subset polarization. The conjugates biased the immune responses towards Th1 and Th17 with respect to the prevalence of interferon‐gamma (IFN‐γ) and interleukin (IL)‐17 (IL‐17) over IL‐4 and IL‐10 levels. The inflammatory activity of...
Source: FEMS Yeast Research - August 12, 2013 Category: Research Authors: Ema Paulovičová, Lucia Paulovičová, Ruzena Pilišiová, Slavomir Bystrický, Dmitri V. Yashunsky, Alexander A. Karelin, Yury E. Tsvetkov, Nikolay E. Nifantiev Tags: Research Article Source Type: research
p53 death signal is mainly mediated by Nuc1(EndoG) in the yeast Saccharomyces cerevisiae
Abstract
The tumor suppressor p53 plays a central role in the regulation of cellular growth and apoptosis. In the yeast Saccharomyces cerevisiae, the overexpression of the human p53 leads to growth inhibition and apoptotic cell death on minimal medium. In the present work, we show that p53‐expressing cells are more susceptible to cell death after an apoptotic stimulus such as H2O2. The analysis of mutants involved in yeast apoptosis‐like death suggests that the observed cell death is Yca1 independent and mainly mediated through Nuc1p. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - August 12, 2013 Category: Research Authors: Vanessa Palermo, Eleonora Mangiapelo, Cristina Piloto, Luisa Pieri, Michela Muscolini, Loretta Tuosto, Cristina Mazzoni Tags: Research Article Source Type: research
Clinical isolates and laboratory reference Candida species and strains have varying abilities to form biofilms
In conclusion, Candida laboratory reference strains and clinical isolates have been shown to form biofilms at different rates, hence for validity, the selection of laboratory reference strains in biofilm studies may be critical for virulence assessment.
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - August 11, 2013 Category: Research Authors: Ali D. Alnuaimi, Neil M. O'Brien‐Simpson, Eric C. Reynolds, Michael J. McCullough Tags: Research Paper Source Type: research
p53 death signal is mainly mediated by Nuc1(EndoG) in the yeast S. cerevisiae
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - August 1, 2013 Category: Research Authors: Vanessa Palermo, Eleonora Mangiapelo, Cristina Piloto, Luisa Pieri, Michela Muscolini, Loretta Tuosto, Cristina Mazzoni Tags: Research Paper Source Type: research
Cellular responses to L‐serine in Saccharomyces cerevisiae: roles of general amino acid control, compartmentalization, and aspartate synthesis
Abstract
In addition to its other roles, l‐serine functions in one‐carbon metabolism and is interconvertable with glycine via serine hydroxymethyltransferases. However, the transcriptional response by Saccharomyces cerevisiae to l‐serine addition is markedly different from that to glycine, with l‐serine acting as a nutrient source rather than one‐carbon units. Following addition of excess l‐serine, 743 genes showed significant expression changes. Induced functions included amino acid synthesis, some stress responses, and FeS metabolism, while ribosomal RNA processing, ribosome biogenesis and hexose transport we...
Source: FEMS Yeast Research - July 29, 2013 Category: Research Authors: Johnny C.‐Y. Lee, Abraham Tsoi, Geoffrey D. Kornfeld, Ian W. Dawes Tags: Research Article Source Type: research
Genetic structure of Kurtzmaniella cleridarum, a cactus flower beetle yeast of the Sonoran and Mojave Deserts: speciation by distance?
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - July 23, 2013 Category: Research Authors: Marc‐André Lachance, Ami M. Perri, Amy S. Farahbakhsh, William T. Starmer Tags: Research Paper Source Type: research
Synthetically prepared glycooligosaccharides mimicking Candida albicans cell wall glycan antigens ‐ novel tools to study host‐pathogen interactions
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - July 18, 2013 Category: Research Authors: E. Paulovičová, L. Paulovičová, R. Pilišiová, S. Bystrický, D. V. Yashunsky, A.A. Karelin, Y.E. Tsvetkov, N.E. Nifantiev Tags: Research Paper Source Type: research
Cell length growth in fission yeast: an analysis of its bilinear character and the nature of its rate change transition
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - July 13, 2013 Category: Research Authors: Anna Horváth, Anna Rácz‐Mónus, Peter Buchwald, Ákos Sveiczer Tags: Research Paper Source Type: research
Cellular responses to L‐serine in Saccharomyces cerevisiae: roles of general amino acid control, compartmentalization and aspartate synthesis
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - July 9, 2013 Category: Research Authors: Johnny Chien‐Yi Lee, Abraham Tsoi, Geoffrey D. Kornfeld, Ian W. Dawes Tags: Research Paper Source Type: research
Molecular characterization of the heteromeric coenzyme A‐synthesizing protein complex (CoA‐SPC) in the yeast Saccharomyces cerevisiae
Abstract
Coenzyme A (CoA) as an essential cofactor for acyl and acetyl transfer reactions is synthesized in five enzymatic steps from pantothenate, cysteine, and ATP. In the yeast Saccharomyces cerevisiae, products of five essential genes CAB1‐CAB5 (coenzyme A biosynthesis) are required to catalyze CoA biosynthesis. In addition, nonessential genes SIS2 and VHS3 similar to CAB3 are also involved. Using epitope‐tagged variants of Cab3 and Cab5, we show that both proteins cofractionate upon chromatographic separation, forming a complex of about 330 kDa. We thus systematically investigated interactions among Cab proteins. ...
Source: FEMS Yeast Research - July 5, 2013 Category: Research Authors: Judith Olzhausen, Tom Moritz, Tim Neetz, Hans‐Joachim Schüller Tags: Research Article Source Type: research
Assessment of the Brettanomyces bruxellensis metabolome during sulphur dioxide exposure
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - June 28, 2013 Category: Research Authors: Ileana Vigentini, C.M. Lucy Joseph, Claudia Picozzi, Roberto Foschino, Linda F. Bisson Tags: Research Paper Source Type: research
XYLH encodes a xylose/H+ symporter from the highly related yeast species Debaryomyces fabryi and Debaryomyces hansenii
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - June 28, 2013 Category: Research Authors: Danielly Ferreira, Alexandra Nobre, Marta Luisa Silva, Joana Tulha, Fábio Faria‐Oliveira, Célia Ferreira, Cândida Lucas Tags: Research Paper Source Type: research
Molecular characterization of the heteromeric coenzyme A synthesizing protein complex (CoA‐SPC) in the yeast Saccharomyces cerevisiae
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - June 22, 2013 Category: Research Authors: Judith Olzhausen, Tom Moritz, Tim Neetz, Hans‐Joachim Schüller Tags: Research Paper Source Type: research
