ENV7 and YCK3, which encode vacuolar membrane protein kinases, genetically interact to impact cell fitness and vacuole morphology
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - December 1, 2013 Category: Research Authors: Surya P Manandhar, Editte Gharakhanian Tags: Research Paper Source Type: research

Phenylethanol promotes adhesion and biofilm formation of the antagonistic yeast Kloeckera apiculata for the control of blue mold on citrus
This study provides a new model system of the biology of the antagonist–pathogen interactions that occur in the antagonistic yeast K. apiculata for the control of blue mold on citrus caused by Penicillium italicum. This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - December 1, 2013 Category: Research Authors: Pu Liu, Jingfan Fang, Kai Chen, Chao‐an Long, Yunjiang Cheng Tags: Research Paper Source Type: research

TpBGL2 codes for a Tetrapisispora phaffii killer toxin active against wine spoilage yeasts
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - November 29, 2013 Category: Research Authors: Lucia Oro, Severino Zara, Francesca Fancellu, Ilaria Mannazzu, Marilena Budroni, Maurizio Ciani, Francesca Comitini Tags: Research Paper Source Type: research

Management of the ER Stress by Activation of the Heat Shock Response in Yeast
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - November 14, 2013 Category: Research Authors: Jin Hou, Hongting Tang, Zihe Liu, Tobias Österlund, Jens Nielsen, Dina Petranovic Tags: Research Paper Source Type: research

Synteny analysis provides a route to design genus‐specific PCR primers for rapid identification of all Saccharomyces species
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - November 12, 2013 Category: Research Authors: Ben Sharpe, Michelle Hulin, James Thorne‐Wallis, Alan Wheals Tags: Research Paper Source Type: research

Human ribosomal protein L9 is a Bax suppressor that promotes cell survival in yeast
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - November 8, 2013 Category: Research Authors: Rawan Eid, Sara Sheibani, Nada Gharib, Jason Lapointe, Avital Horowitz, Hojatollah Vali, Craig A. Mandato, Michael T. Greenwood Tags: Research Paper Source Type: research

Cell density impacts Candida glabrata survival in hypo osmotic stress
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - November 8, 2013 Category: Research Authors: Hala Almshawit, Dodie Pouniotis, Ian Macreadie Tags: Research Paper Source Type: research

An Autonomously Replicating Sequence for use in a wide range of budding yeasts.
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - November 1, 2013 Category: Research Authors: Ivan Liachko, Maitreya J. Dunham Tags: Short Communication Source Type: research

Squalene epoxidase as a target for manipulation of squalene levels in the yeast Saccharomyces cerevisiae
Abstract Squalene is a valuable natural substance with several biotechnological applications. In the yeast Saccharomyces cerevisiae, it is produced in the isoprenoid pathway as the first precursor dedicated to ergosterol biosynthesis. The aim of this study was to explore the potential of squalene epoxidase encoded by the ERG1 gene as the target for manipulating squalene levels in yeast. Highest squalene levels (over 1000 μg squalene per 109 cells) were induced by specific point mutations in ERG1 gene that reduced activity of squalene epoxidase and caused hypersensitivity to terbinafine. This accumulation of squalene in ...
Source: FEMS Yeast Research - October 30, 2013 Category: Research Authors: Martina Garaiová, Veronika Zambojová, Zuzana Šimová, Peter Griač, Ivan Hapala Tags: Research Article Source Type: research

Rebels with a cause: molecular features and physiological consequences of yeast prions
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - October 27, 2013 Category: Research Authors: David M. Garcia, Daniel F. Jarosz Tags: MiniReview Source Type: research

Phenotypical properties associated with virulence from clinical isolates belonging to the Candida parapsilosis complex
Abstract The production of virulence attributes in three reference strains and 11 clinical isolates primarily identified as Candida parapsilosis was evaluated. Morphological and phenotypical tests were not able to discriminate among the three species of the C. parapsilosis complex; consequently, molecular methods were applied to solve this task. After employing polymerase chain reaction‐based methods, nine clinical strains were identified as C. parapsilosis sensu stricto and two as C. orthopsilosis. Protease, catalase, and hemolysin were produced by all 14 strains, while 92.9% and 78.6% of strains secreted, respective...
Source: FEMS Yeast Research - October 25, 2013 Category: Research Authors: Érika A. Abi‐chacra, Lucieri O.P. Souza, Lucas P. Cruz, Lys A. Braga‐Silva, Diego S. Gonçalves, Cátia L. Sodré, Marcos D. Ribeiro, Sergio H. Seabra, Maria H.G. Figueiredo‐Carvalho, Leonardo S. Barbedo, Rosely M. Zancopé‐Oliveira, Mariangela Z Tags: Research Article Source Type: research

Solvent‐exposed serines in the Gal4 DNA‐binding domain are required for promoter occupancy and transcriptional activation in vivo
Abstract The yeast transcriptional activator Gal4 has long been the prototype for studies of eukaryotic transcription. Gal4 is phosphorylated in the DNA‐binding domain (DBD); however, the molecular details and functional significance of this remain unknown. We mutagenized seven potential phosphoserines that lie on the solvent‐exposed face of the DBD structure and assessed them for transcriptional activity and DNA binding in vivo. Serine to alanine mutants at positions 22, 47, and 85 show the greatest reduction in promoter occupancy and transcriptional activity at the MEL1 promoter containing a single UASGAL. Substituti...
Source: FEMS Yeast Research - October 25, 2013 Category: Research Authors: Branka Jeličić, Josipa Nemet, Ana Traven, Mary Sopta Tags: Research Article Source Type: research

Aging and Cell Death in the Other Yeasts, Schizosaccharomyces pombe and Candida albicans
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - October 25, 2013 Category: Research Authors: Su‐Ju Lin, Nicanor Austriaco Tags: MiniReview Source Type: research

Cellular Redox Homeostasis, Reactive Oxygen Species and Replicative Ageing in Saccharomyces cerevisiae
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - October 25, 2013 Category: Research Authors: Anita Ayer, Campbell W. Gourlay, Ian W. Dawes Tags: MiniReview Source Type: research

Yeast Sirtuins and the Regulation of Aging
This article is protected by copyright. All rights reserved. (Source: FEMS Yeast Research)
Source: FEMS Yeast Research - October 25, 2013 Category: Research Authors: Margaret B. Wierman, Jeffrey S. Smith Tags: MiniReview Source Type: research