FEMS Immunology and Medical Microbiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Lipidation of the FPI protein IglE contributes to Francisella tularensis ssp. novicida intramacrophage replication and virulence
Abstract Francisella tularensis is a Gram‐negative bacterium responsible for the human disease tularemia. The Francisella pathogenicity island (FPI) encodes a secretion system related to type VI secretion systems (T6SS) which allows F. tularensis to escape the phagosome and replicate within the cytosol of infected macrophages and ultimately cause disease. A lipoprotein is typically found encoded within T6SS gene clusters and is believed to anchor portions of the secretion apparatus to the outer membrane. We show that the FPI protein IglE is a lipoprotein that incorporates 3H‐palmitate and localizes to the outer membra...
Source: FEMS Immunology and Medical Microbiology - May 8, 2014 Category: Microbiology Authors: Jesse Q. Nguyen, Ryan P. Gilley, Xhavit Zogaj, Stephen A. Rodriguez, Karl E. Klose Tags: Research Article Source Type: research

Involvement of toxin–antitoxin modules in Burkholderia cenocepacia biofilm persistence
In this study, we investigated whether TA modules contribute to persistence toward antibiotics in Burkholderia cenocepacia J2315. Sixteen pairs of genes were identified based on their apparent similarity to TA modules. Overexpression of the putative toxins had various effects on growth, persistence, and biofilm formation. Toxins, whose overexpression resulted in growth inhibition, often increased the number of surviving persisters; in contrast, overexpression of putative toxins showing no effects on growth had no positive influence on the number of surviving persisters. Furthermore, the expression of the TA modules was com...
Source: FEMS Immunology and Medical Microbiology - April 28, 2014 Category: Microbiology Authors: Heleen Van Acker, Andrea Sass, Inne Dhondt, Hans J. Nelis, Tom Coenye Tags: Research Article Source Type: research

Growth, motility and resistance to oxidative stress of the melioidosis pathogen Burkholderia pseudomallei is enhanced by epinephrine
This study provides the first evidence that epinephrine, a hormone released from the host under stress and upon therapy, can affect B. pseudomallei virulence‐associated properties. This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - April 17, 2014 Category: Microbiology Authors: Narin Intarak, Veerachat Muangsombut, Paiboon Vattanaviboon, Mark P. Stevens, Sunee Korbsrisate Tags: Research Paper Source Type: research

Microbial biofilms – the coming of age of a research field
(Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - April 10, 2014 Category: Microbiology Authors: Tom Coenye, Patrick Van Dijck, Thomas Bjarnsholt, Ake Forsberg Tags: Editorial Source Type: research

Issue Information
(Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - April 10, 2014 Category: Microbiology Tags: Issue Information Source Type: research

Systems kinomics for characterizing host responses to high‐consequence pathogens at the NIH/NIAID Integrated Research Facility‐Frederick
Abstract Currently, there is a paucity of information regarding the molecular pathogenesis for many high‐consequence pathogens (HCPs) that pose threats to both national and international public health. In spite of this, investigations of the molecular pathogenesis for many HCPs have been limited to gross pathological changes in animal models or global analysis of gene expression. Further, questions remain regarding the ability of animal models of disease to recapitulate human molecular pathogenesis or act as predictors of therapeutic efficacy. Thus, it is likely that medical countermeasure development for HCPs will rely ...
Source: FEMS Immunology and Medical Microbiology - April 10, 2014 Category: Microbiology Authors: Jason Kindrachuk, Shane Falcinelli, Jiro Wada, Jens H. Kuhn, Lisa E. Hensley, Peter B. Jahrling Tags: MiniReview Source Type: research

The emergence of the Middle East Respiratory Syndrome coronavirus
Abstract On September 20, 2012, a Saudi Arabian physician reported the isolation of a novel coronavirus from a patient with pneumonia on ProMED‐mail. Within a few days, the same virus was detected in a Qatari patient receiving intensive care in a London hospital, a situation reminiscent of the role air travel played in the spread of severe acute respiratory syndrome coronavirus (SARS‐CoV) in 2002. SARS‐CoV originated in China's Guangdong Province and affected more than 8000 patients in 26 countries before it was contained 6 months later. Over a year after the emergence of this novel coronavirus – Middle East respi...
Source: FEMS Immunology and Medical Microbiology - April 9, 2014 Category: Microbiology Authors: Shauna Milne‐Price, Kerri L. Miazgowicz, Vincent J. Munster Tags: MiniReview Source Type: research

Remote monitoring of the progression of primary pneumonic plague in Brown Norway rats in high‐capacity, high‐containment housing
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - April 9, 2014 Category: Microbiology Authors: Eric A. Coate, Andrew G. Kocsis, Kristen N. Peters, Paul E. Anderson, Mark R. Ellersieck, Deborah M. Fine, Deborah M. Anderson Tags: Research Paper Source Type: research

Detection and functionality of the cdtB, pltA and pltB from Salmonella enterica serovar Javiana
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - April 1, 2014 Category: Microbiology Authors: Ezat H. Mezal, Dongryeoul Bae, Ashraf A. Khan Tags: Research Paper Source Type: research

Low‐dose cisplatin administration to septic mice improves bacterial clearance and programs peritoneal macrophage polarization to M1 phenotype
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - April 1, 2014 Category: Microbiology Authors: Yanyan Li, Zhenling Wang, Xuelei Ma, Bin shao, Xiang Gao, Binglan Zhang, Guangchao Xu, Yuquan Wei Tags: Research Paper Source Type: research

Catheter‐Related Infections Caused by Pseudomonas aeruginosa: Virulence Factors Involved and their Relationships
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - April 1, 2014 Category: Microbiology Authors: Katerina Olejnickova, Veronika Hola, Filip Ruzicka Tags: Research Paper Source Type: research

In Vivo Imaging in an ABSL‐3 Regional Biocontainment Laboratory
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - April 1, 2014 Category: Microbiology Authors: Charles A. Scanga, Brian J. Lopresti, Jaime Tomko, Lonnie James Frye, Teresa M. Coleman, Daniel Fillmore, Jonathan P. Carney, Philana L. Lin, JoAnne L. Flynn, Christina L. Gardner, Chengqun Sun, William B. Klimstra, Kate D. Ryman, Douglas S. Reed, Daniel Tags: MiniReview Source Type: research

Chlamydia Pneumoniae Infection of Lungs and Macrophages Indirectly Stimulates the Phenotypic Conversion of Smooth Muscle Cells and Mesenchymal Stem Cells: Potential Roles in Vascular Calcification and Fibrosis
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - April 1, 2014 Category: Microbiology Authors: Sarah Cabbage, Nicholas Ieronimakis, Michael Preusch, Amy Lee, Jerry Ricks, Kajohnkiart Janebodin, Aislinn Hays, Errol S. Wijelath, Morayma Reyes, Lee Ann Campbell, Michael E. Rosenfeld Tags: Research Paper Source Type: research

LEAP‐2, LL‐37 and RNase7 in tonsillar tissue: downregulated expression in seasonal allergic rhinitis
ConclusionThe present study demonstrates the presence and function of LEAP‐2, LL‐37 and RNase7 in tonsils. Moreover, a downregulation of LEAP‐2 and RNase7 is seen in SAR patients, indicating that allergic individuals may be more susceptible to respiratory tract infections due to an impaired antimicrobial defense.This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - April 1, 2014 Category: Microbiology Authors: Jesper Bogefors, Anne Månsson Kvarnhammar, Camilla Rydberg Millrud, Susanna Kumlien Georén, Lars Olaf Cardell Tags: Research Paper Source Type: research

Prior to Foxp3+ regulatory T cells induction, IL‐10‐producing B cells expanded after Helicobacter pylori infection
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - April 1, 2014 Category: Microbiology Authors: Lumin Wei, Jingtong Wang, Yulan Liu Tags: Research Paper Source Type: research