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Susceptibility genes are enriched in those of the HSV‐1/host interactome in psychiatric and neurological disorders
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - August 3, 2013 Category: Microbiology Authors: C.J. Carter Tags: Research Paper Source Type: research

Interaction of Cryptosporidium parvum with mouse dendritic cells leads to their activation and parasite transportation to mesenteric lymph nodes
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - August 3, 2013 Category: Microbiology Authors: Gregorio Perez‐Cordon, Guilin Yang, Boping Zhou, Weijia Nie, Shan Li, Lianfa Shi, Saul Tzipori, Hanping Feng Tags: Research Paper Source Type: research

Identification of a protective protein from stationary phase exoproteome of Brucella abortus
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - August 3, 2013 Category: Microbiology Authors: Shikha Jain, Subodh Kumar, Sudhir Dohre, Prachiti Afley, Nabonita Sengupta, Syed Imteyaz Alam Tags: Research Paper Source Type: research

Plasmid deficiency in urogenital isolates of Chlamydia trachomatis reduces infectivity and virulence in a mouse model
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - August 1, 2013 Category: Microbiology Authors: Ira M. Sigar, Justin H. Schripsema, Yibing Wang, Ian N. Clarke, Lesley T. Cutcliffe, Helena M.B. Seth‐Smith, Nicholas R. Thomson, Carina Bjartling, Magnus Unemo, Kenneth Persson, Kyle H. Ramsey Tags: Research Paper Source Type: research

Identification of immunoreactive proteins of Streptococcus agalactiae isolated from cultured tilapia in China
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - August 1, 2013 Category: Microbiology Authors: Guangjin Liu, Wei Zhang, Chengping Lu Tags: Research Paper Source Type: research

Predicting the host protein interactors of Chandipura virus using a structural similarity–based approach
Abstract Chandipura virus (CHPV), alike other pathogens, exploits the cellular infrastructure of their hosts through complex network of interactions for successful infection. CHPV being a recently emerged pediatric encephalitic virus, the mechanisms involved in the establishment of viral persistence are still ill defined. Because the protein interface between CHPV and its host provides one means by which the virus invades and seize control of their human host machinery, the authors in this study have employed computational methods to create a network of putative protein–protein interactions between CHPV and its human hos...
Source: FEMS Immunology and Medical Microbiology - July 29, 2013 Category: Microbiology Authors: Sreejith Rajasekharan, Jyoti Rana, Sahil Gulati, Sanjeev K. Sharma, Vandana Gupta, Sanjay Gupta Tags: Research Article Source Type: research

Analysis of the Staphylococcus aureus abscess proteome identifies antimicrobial host proteins and bacterial stress responses at the host–pathogen interface
Abstract Abscesses are a hallmark of invasive staphylococcal infections and the site of a dynamic struggle between pathogen and host. However, the precise host and bacterial factors that contribute to abscess formation and maintenance have not been completely described. In this work, we define the Staphylococcus aureus abscess proteome from both wild‐type and neutropenic mice to elucidate the host response to staphylococcal infection and uncover novel S. aureus virulence factors. Among the proteins identified, the mouse protein histone H4 was enriched in the abscesses of wild‐type compared with neutropenic animals. Hi...
Source: FEMS Immunology and Medical Microbiology - July 29, 2013 Category: Microbiology Authors: Ahmed S. Attia, James E. Cassat, Sheg O. Aranmolate, Lisa J. Zimmerman, Kelli L. Boyd, Eric P. Skaar Tags: Research Article Source Type: research

Bordetella pertussis entry into respiratory epithelial cells and intracellular survival
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Source: FEMS Immunology and Medical Microbiology - July 29, 2013 Category: Microbiology Authors: Yanina Lamberti, Juan Gorgojo, Cintia Massillo, Maria Eugenia Rodriguez Tags: Research Paper Source Type: research

Chlamydia pneumoniae induces expression of pro‐atherogenic factors through activation of the lectin‐like oxidized LDL receptor‐1
Abstract Several lines of evidence have associated Chlamydia pneumoniae with cardiovascular disease including acceleration of atherosclerotic lesion progression in hyperlipidemic animal models by infection. Many of the pro‐atherogenic effects of oxidized low‐density lipoprotein (ox‐LDL) occur through the activation of the lectin‐like ox‐LDL receptor‐1 (LOX‐1). Chlamydia pneumoniae upregulates the expression of the LOX‐1 mRNA, promotes the uptake of ox‐LDL, and utilizes the LOX‐1 receptor for infectivity. The overall goal of this study was to determine whether C. pneumoniae organisms upregulated LOX‐1...
Source: FEMS Immunology and Medical Microbiology - July 26, 2013 Category: Microbiology Authors: Lee A. Campbell, Amy W. Lee, Michael E. Rosenfeld, Cho‐chou Kuo Tags: Research Article Source Type: research

Leaf extract of Azadirachta indica (neem): a potential antibiofilm agent for Pseudomonas aeruginosa
This study evaluated the role of neem in inhibiting biofilm formation by P. aeruginosa. Factors contributing to adherence and biofilm formation were also studied. Results demonstrated that neem leaves extract was quite effective in disrupting formation and structure of biofilms. Moreover, the level of exopolysaccharide, alginate, hydrophobic interactions and uroepithelial cell attachment, which contributes to biofilm formation, was also affected significantly. Results confirm the effectiveness of neem extract in inhibiting biofilm formation. Such studies can lead to the discovery of safe antimicrobial drugs from natural s...
Source: FEMS Immunology and Medical Microbiology - July 25, 2013 Category: Microbiology Authors: Kusum Harjai, Anju Bala, Ravi K. Gupta, Radhika Sharma Tags: Short Communication Source Type: research

Dientamoeba fragilis DNA detection in Enterobius vermicularis eggs
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Source: FEMS Immunology and Medical Microbiology - July 25, 2013 Category: Microbiology Authors: Jessica Ögren, Olaf Dienus, Sture Löfgren, Peter Iveroth, Andreas Matussek Tags: Short Communication Source Type: research

The protective effect of immunoglobulin in murine tuberculosis is dependent on IgG glycosylation
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - July 24, 2013 Category: Microbiology Authors: Nesty Olivares, Brenda Marquina, Dulce Mata Espinoza, Zyanya Lucia Zatarain‐Barron, Clara Espitia Pinzón, Iris Estrada, Cristina Parada, Mattias Collin, Graham Rook, Rogelio Hernandez‐Pando Tags: Research Paper Source Type: research

Pathogen levels and clinical response to periodontal treatment in patients with Interleukin 8 haplotypes
Abstract The aim of this study was to investigate the effect of non‐surgical treatment of periodontitis on the levels of periodontopathogens and clinical parameters in patients with different genetic backgrounds produced by polymorphisms in the Interleukin (IL8) gene. Thirty patients grouped according to IL8 ATC/TTC or AGT/TTC haplotypes were submitted to non‐surgical periodontal treatment. Levels of Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola were determined in 240 subgingival plaque samples by qPCR. The association between IL8 haplotypes and the levels of periodontopathogens and clinical p...
Source: FEMS Immunology and Medical Microbiology - July 22, 2013 Category: Microbiology Authors: Livia S. Finoti, Sâmia C.T. Corbi, Giovana Anovazzi, Silvia R.L. Teixeira, Marisa V. Capela, Márcia H. Tanaka, Yeon J. Kim, Silvana R.P. Orrico, Joni A. Cirelli, Marcia P.A. Mayer, Raquel M. Scarel‐Caminaga Tags: Research Article Source Type: research

Host Organelle Hijackers: a similar modus operandi for Toxoplasma gondii and Chlamydia trachomatis: co‐infection model as a tool to investigate pathogenesis
Abstract The bacterium Chlamydia trachomatis and the protozoan parasite Toxoplasma gondii are the causative agents of chlamydiosis and toxoplasmosis in humans, respectively. Both microorganisms are obligate intracellular pathogens and notorious for extensively modifying the cytoskeletal architecture and the endomembrane system of their host cells to establish productive infections. This review highlights the similar tactics developed by these two pathogens to manipulate their host cell despite their genetic unrelatedness. Using an in vitro cell culture model whereby single fibroblasts are infected by C. trachomatis and T....
Source: FEMS Immunology and Medical Microbiology - July 22, 2013 Category: Microbiology Authors: Julia D. Romano, Isabelle Coppens Tags: MiniReview Source Type: research

Peptide matching between Epstein‐Barr virus and human proteins
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - July 19, 2013 Category: Microbiology Authors: Giovanni Capone, Michele Calabrò, Guglielmo Lucchese, Candida Fasano, Bruna Girardi, Lorenzo Polimeno, Darja Kanduc Tags: Short Communication Source Type: research