LEAP‐2, LL‐37 and RNase7 in tonsillar tissue: downregulated expression in seasonal allergic rhinitis

ConclusionThe present study demonstrates the presence and function of LEAP‐2, LL‐37 and RNase7 in tonsils. Moreover, a downregulation of LEAP‐2 and RNase7 is seen in SAR patients, indicating that allergic individuals may be more susceptible to respiratory tract infections due to an impaired antimicrobial defense.This article is protected by copyright. All rights reserved.

Source: FEMS Immunology and Medical Microbiology - April 1, 2014 Category: Microbiology Authors: Jesper Bogefors, Anne Månsson Kvarnhammar, Camilla Rydberg Millrud, Susanna Kumlien Georén, Lars Olaf Cardell Tags: Research Paper Source Type: research