Polymorphisms of OCT1 and ABCG2 are associated with Lamotrigine concentrations in Chinese patients with epilepsy
(Source: Epilepsy Research)
Source: Epilepsy Research - August 31, 2016 Category: Neurology Authors: Chun-Hong Shen, Yin-Xi Zhang, Ru-Yi Lu, Bo Jin, Shan Wang, Zhi-Rong Liu, Ye-Lei Tang, Mei-Ping Ding Source Type: research

Time Interval Providing Highest Yield for Initial EEG in Patients with New Onset Seizures
(Source: Epilepsy Research)
Source: Epilepsy Research - August 29, 2016 Category: Neurology Authors: Pooja Sofat, Barbara Teeter, Katelyn S. Kavak, Rajesh Gupta, Ping Li Source Type: research

The cannabinoid CB2 receptor-specific agonist AM1241 increases pentylenetetrazole-induced seizure severity in Wistar rats
(Source: Epilepsy Research)
Source: Epilepsy Research - August 28, 2016 Category: Neurology Authors: Cristiane R. de Carvalho, Alexandre A. Hoeller, Pedro L.C. Franco, Athos P.S. Martini, Fl ávia M.S. Soares, Katia Lin, Rui D. Prediger, Benjamin J. Whalley, Roger Walz Source Type: research

Alterations in BRAF gene, and enhanced mTOR and MAPK signaling in dysembryoplastic neuroepithelial tumors (DNTs)
(Source: Epilepsy Research)
Source: Epilepsy Research - August 27, 2016 Category: Neurology Authors: Aanchal Kakkar, Atreye Majumdar, Anupam Kumar, Manjari Tripathi, Pankaj Pathak, Mehar C. Sharma, Vaishali Suri, Vivek Tandon, Sarat P. Chandra, Chitra Sarkar Source Type: research

Acute Postoperative Seizures as Predictors of Seizure Outcomes after Epilepsy Surgery
(Source: Epilepsy Research)
Source: Epilepsy Research - August 23, 2016 Category: Neurology Authors: Nisha Giridharan, Paul S. Horn, Hansel M. Greiner, Katherine D. Holland, Francesco T. Mangano, Ravindra Arya Source Type: research

Influence of antiepileptic drugs on serum lipid levels in adult epilepsy patients
(Source: Epilepsy Research)
Source: Epilepsy Research - August 23, 2016 Category: Neurology Authors: Yoshiaki Yamamoto, Kiyohito Terada, Yukitoshi Takahashi, Katsumi Imai, Yoshiyuki Kagawa, Yushi Inoue Source Type: research

H1 histamine receptor densities are increased in brain regions of rats with genetically generalized epilepsies
(Source: Epilepsy Research)
Source: Epilepsy Research - August 23, 2016 Category: Neurology Authors: Inna S. Midzyanovskaya, Lidia M. Birioukova, Alla B Shatskova, Gilles van Luijtelaar, Leena M Tuomisto Source Type: research

Status epilepticus in the elderly —A retrospective study on 120 patients
Status epilepticus (SE) can be regarded as the most severe form of seizure and is often the expression of an acute and life-threatening brain disorder with mortality rates up to 22% (De Lorenzo et al., 1996; Logroscino et al., 2005, 1997; Shorvon, 1994a). SE shows a bimodal distribution with the highest icidence in children   (Source: Epilepsy Research)
Source: Epilepsy Research - August 22, 2016 Category: Neurology Authors: Alexandra Rohracher, Doris P. Reiter, Francesco Brigo, Gudrun Kalss, Aljoscha Thomschewski, Helmut Novak, Alexander Zerbs, Judith Dobesberger, Aynur Akhundova, Julia H öfler, Giorgi Kuchukhidze, Markus Leitinger, Eugen Trinka Source Type: research

Effect of diclofenac sodium on seizures and inflammatory profile induced by kindling seizure model
Epilepsy is a neurological disorder characterized by spontaneous and recurrent seizure episodes (Fisher et al., 2005) that affects between 1 –2% of the world population. So far, there is no cure and the treatments with anticonvulsants are not totally efficacious for the different types of epilepsy (López-Hernández et al., 2005). The side effects of tolerance, dependence, risk of death, physical injury (due to the episodes), cerebral damage and induction of psychotic reactions become a problem for clinical treatment. (Source: Epilepsy Research)
Source: Epilepsy Research - August 22, 2016 Category: Neurology Authors: Vin ícius Vieira, Dreicy Glassmann, Paula Marafon, Patricia Pereira, Rosane Gomez, Adriana Simon Coitinho Source Type: research

Status epilepticus in the elderly − a retrospective study on 120 patients
(Source: Epilepsy Research)
Source: Epilepsy Research - August 22, 2016 Category: Neurology Authors: Alexandra Rohracher, Doris P. Huber, Francesco Brigo, Gudrun Kalss, Aljoscha Thomschewski, Helmut Novak, Alexander Zerbs, Judith Dobesberger, Aynur Akhundova, Julia H öfler, Giorgi Kuchukhidze, Markus Leitinger, Eugen Trinka Source Type: research

Pharmacokinetics, exposure –cognition, and exposure–efficacy relationships of perampanel in adolescents with inadequately controlled partial-onset seizures
(Source: Epilepsy Research)
Source: Epilepsy Research - August 22, 2016 Category: Neurology Authors: Vicente Villanueva, Oneeb Majid, Charcrin Nabangchang, Haichen Yang, Antonio Laurenza, Jim Ferry, Ziad Hussein Source Type: research

Outcome of initial antiepileptic drug treatment in elderly patients with newly diagnosed epilepsy
(Source: Epilepsy Research)
Source: Epilepsy Research - August 20, 2016 Category: Neurology Authors: Emmi Bruun, Reetta K älviäinen, Tapani Keränen Source Type: research

Tolerability, safety, and efficacy of adjunctive brivaracetam for focal seizures in older patients: A pooled analysis from three phase III studies
Epilepsy is common in older adults; causes of new-onset epilepsy at older ages include cerebrovascular disease, dementia, Alzheimer ’s, brain tumor, primary neurodegenerative disorders, and traumatic head injury (Brodie et al., 2009; Pugh et al., 2009). The incidence of treated epilepsy has been estimated at 80.8 per 100,000 in the general population, rising to 85.9 per 100,000 in those aged 65–69 years, and 135.4 per 100,00 0 in people ≥85 years (Wallace et al., 1998). In addition to older patients with new-onset epilepsy, the population of older adults with epilepsy also includes those who have been treated for man...
Source: Epilepsy Research - August 17, 2016 Category: Neurology Authors: Martin J. Brodie, John Whitesides, Jimmy Schiemann, Joseph D ’souza, Martin E. Johnson Tags: Short communication Source Type: research

Residual Neurogenesis in Chronically Epileptic Hippocampus of Mice
(Source: Epilepsy Research)
Source: Epilepsy Research - August 17, 2016 Category: Neurology Authors: Jian-Xin Liu, Ming Hu, Kun Zhu, Xin-Lin Chen, Jian-Shui Zhang, Bo Yuan, Yong Liu Source Type: research

Effectiveness and tolerability of Perampanel in children and adolescents with refractory epilepsies − an Italian observational multicenter study
(Source: Epilepsy Research)
Source: Epilepsy Research - August 17, 2016 Category: Neurology Authors: P. De Liso, F. Vigevano, N. Specchio, L. De Palma, P. Bonanni, E. Osanni, G. Coppola, P. Parisi, S. Grosso, A. Verrotti, A. Spalice, F. Nicita, N. Zamponi, S. Siliquini, L. Giordano, P. Martelli, R. Guerrini, A. Rosati, L. Ilvento, V. Belcastro, P. Strian Source Type: research