Naringin attenuates granule cell dispersion in the dentate gyrus in a mouse model of temporal lobe epilepsy
(Source: Epilepsy Research)
Source: Epilepsy Research - March 14, 2016 Category: Neurology Authors: Hannah Jang, Kyoung Hoon Jeong, Sang Ryong Kim Tags: Short communication Source Type: research

Unfavorable surgical outcomes in partial epilepsy with secondary bilateral synchrony: Intracranial electroencephalography study
(Source: Epilepsy Research)
Source: Epilepsy Research - March 14, 2016 Category: Neurology Authors: Jun-Sang Sunwoo, Jung-Ick Byun, Jangsup Moon, Jung-Ah Lim, Tae-Joon Kim, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Kon Chu, Manho Kim, Chun-Kee Chung, Ki-Young Jung, Sang Kun Lee Source Type: research

Acute seizures in cerebral venous sinus thrombosis: What predicts it?
Seizures are more specific to cerebral vein and sinus thrombosis (CVST) than to other types of stroke (Conrad et al., 2013). About 12–31.9% of patients with CVST have seizures as the presenting feature of the disease. Among them, 44.3% of patients have seizures in the early stage of the disease (Ferro et al., 2003; Masuhr et al., 2006). The rate of mortality is three times higher in CVST patients with seizures than those without seizures (Masuhr et al., 2006). Seizures in CVST can occur during different periods of the disease's course and can be categorized as either “early/acute seizures”, which take place before th...
Source: Epilepsy Research - March 11, 2016 Category: Neurology Authors: Rohan Mahale, Anish Mehta, Aju Abraham John, Kiran Buddaraju, Abhinandan K. Shankar, Mahendra Javali, Rangasetty Srinivasa Tags: Full length article Source Type: research

Anti-epileptic drugs and bone loss: phenytoin reduces pro-collagen I and alters the electrophoretic mobility of osteonectin in cultured bone cells
(Source: Epilepsy Research)
Source: Epilepsy Research - March 11, 2016 Category: Neurology Authors: Emma L. Wilson, Mark Garton, Heidi R. Fuller Tags: Short communication Source Type: research

Intrapatient variation in antiepileptic drug plasma concentration after generic substitution vs stable brand-name drug regimens
Generic substitution of antiepileptic drugs (AEDs) in the treatment of epilepsy is still controversial due to the lack of consensus and clear guidance for clinicians (Privitera, 2013; Shaw and Hartman, 2010). Retrospective studies and anecdotal reports suggested a potential relationship between brand-name vs generic AED switching and adverse effects, especially loss of seizure control, raising concerns among clinicians and patients about the use of generic formulations. A few prospective randomized studies did not confirm the safety risks shown in observational studies, but they must be considered cautiously due to methodo...
Source: Epilepsy Research - March 2, 2016 Category: Neurology Authors: Manuela Contin, Lucia Alberghini, Carmina Candela, Giulia Benini, Roberto Riva Source Type: research