Tolerability, safety, and efficacy of adjunctive brivaracetam for focal seizures in older patients: A pooled analysis from three phase III studies

Epilepsy is common in older adults; causes of new-onset epilepsy at older ages include cerebrovascular disease, dementia, Alzheimer ’s, brain tumor, primary neurodegenerative disorders, and traumatic head injury (Brodie et al., 2009; Pugh et al., 2009). The incidence of treated epilepsy has been estimated at 80.8 per 100,000 in the general population, rising to 85.9 per 100,000 in those aged 65–69 years, and 135.4 per 100,00 0 in people ≥85 years (Wallace et al., 1998). In addition to older patients with new-onset epilepsy, the population of older adults with epilepsy also includes those who have been treated for many decades.

Source: Epilepsy Research - August 17, 2016 Category: Neurology Authors: Martin J. Brodie, John Whitesides, Jimmy Schiemann, Joseph D ’souza, Martin E. Johnson Tags: Short communication Source Type: research