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Expression of Concern to: Evaluation of patients with multiple sclerosis using reverse nutech functional score and expanded disability status scale after human embryonic stem cell therapy
The Editors-in-Chief of Clinical and Translational Medicine are issuing an editorial expression of concern to alert readers that concerns have been raised regarding the ethics of this study [1]. Appropriate edito... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - September 18, 2017 Category: Internal Medicine Authors: Geeta Shroff Tags: Erratum Source Type: research

Differences in immune response to anesthetics used for day surgery versus hospitalization surgery for breast cancer patients
Surgery/anesthetic technique-stimulated immunosuppression may be associated with outcome for cancer patients. Here, the immune responses of patients undergoing day surgery versus hospitalization surgery for br... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - September 14, 2017 Category: Internal Medicine Authors: Ryungsa Kim, Ami Kawai, Megumi Wakisaka, Yuri Funaoka, Shoichiro Ohtani, Mitsuya Ito, Takayuki Kadoya and Morihito Okada Tags: Research Source Type: research

Profiling of cardio-metabolic risk factors and medication utilisation among Type II diabetes patients in Ghana: a prospective cohort study
Type II diabetes mellitus (T2DM) is complicated by multiple cardio-metabolic risk factors. Controlling these factors requires lifestyle modifications alongside utilisation of anti-diabetic medications. Differe... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - September 7, 2017 Category: Internal Medicine Authors: Eric Adua, Peter Roberts, Samuel Asamoah Sakyi, Francis Agyemang Yeboah, Albert Dompreh, Kwasi Frimpong, Enoch Odame Anto and Wei Wang Tags: Research Source Type: research

The role of lipids in corneal diseases and dystrophies: a systematic review
Corneal diseases are an extensive cause of blindness worldwide and continue to persist as a challenging public health concern. Recently, various lipid-based therapies have been advocated for the modulation of ... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 11, 2017 Category: Internal Medicine Authors: Tyler G. Rowsey and Dimitrios Karamichos Tags: Review Source Type: research

Purified umbilical cord derived mesenchymal stem cell treatment in a case of systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a multiple organ system autoimmune disorder for which there is no known cure. (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 7, 2017 Category: Internal Medicine Authors: Christopher D. Phillips, Pornpatcharin Wongsaisri, Thein Htut and Terry Grossman Tags: Case report Source Type: research

The role of heterogeneity in asthma: a structure-to-function perspective
A number of methods have evolved through the years in probing the dysfunction that impacts mechanics and ventilation in asthma. What has been consistently found is the notion of heterogeneity that is not only ... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 3, 2017 Category: Internal Medicine Authors: Justin K. Lui and Kenneth R. Lutchen Tags: Review Source Type: research

Styrene maleic acid encapsulated raloxifene micelles for management of inflammatory bowel disease
Inflammatory bowel disease (IBD) comprises a group of disorders that manifest through chronic inflammation of the colon and small intestine. Although the exact cause of IBD is still unclear, dysfunctional immu... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 3, 2017 Category: Internal Medicine Authors: Khaled Greish, Safa Taha, Anfal Jasim, Sara Abd Elghany, Ameera Sultan, Ali AlKhateeb, Manal Othman, Fang Jun, Sebastien Taurin and Moiz Bakhiet Tags: Research Source Type: research

Lipidomics and anti-trypanosomatid chemotherapy
Trypanosomatids such as Leishmania, Trypanosoma brucei and Trypanosoma cruzi belong to the order Kinetoplastida and are the source of many significant human and animal diseases. Current treatment is unsatisfactor... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 1, 2017 Category: Internal Medicine Authors: Michael Biagiotti, Sedelia Dominguez, Nader Yamout and Rachel Zufferey Tags: Review Source Type: research

CXCL9-11 polymorphisms are associated with liver fibrosis in patients with chronic hepatitis C: a cross-sectional study
In this study, we analyzed the association between CXCL9-11 polymorphism... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - July 28, 2017 Category: Internal Medicine Authors: Mar ía Ángeles Jiménez-Sousa, Ana Zaida Gómez-Moreno, Daniel Pineda-Tenor, Luz Maria Medrano, Juan José Sánchez-Ruano, Amanda Fernández-Rodríguez, Tomas Artaza-Varasa, José Saura-Montalban, Sonia Vázquez-Morón, Pablo Ryan and Salvador Resino Tags: Research Source Type: research

Significance of long chain polyunsaturated fatty acids in human health
In the last decades, the development of new technologies applied to lipidomics has revitalized the analysis of lipid profile alterations and the understanding of the underlying molecular mechanisms of lipid me... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - July 27, 2017 Category: Internal Medicine Authors: Rafael Z árate, Nabil el Jaber-Vazdekis, Noemi Tejera, José A. Pérez and Covadonga Rodríguez Tags: Review Source Type: research

Autophagy and inflammation
Autophagy is a homeostatic mechanism involved in the disposal of damaged organelles, denatured proteins as well as invaded pathogens through a lysosomal degradation pathway. Recently, increasing evidences have... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - July 26, 2017 Category: Internal Medicine Authors: Mengjia Qian, Xiaocong Fang and Xiangdong Wang Tags: Review Source Type: research

Systems and precision medicine approaches to diabetes heterogeneity: a Big Data perspective
Big Data, and in particular Electronic Health Records, provide the medical community with a great opportunity to analyze multiple pathological conditions at an unprecedented depth for many complex diseases, in... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - July 25, 2017 Category: Internal Medicine Authors: Enrico Capobianco Source Type: research

Biofluid lipidome: a source for potential diagnostic biomarkers
Lipidomics is the identification and quantitation of changes in the lipidome of a cell, tissue, organ or biofluid in health and disease using high resolution mass spectrometry. Lipidome of a particular organis... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - June 20, 2017 Category: Internal Medicine Authors: Arkasubhra Ghosh and Krishnatej Nishtala Source Type: research

IFN γ-producing CD4+ T lymphocytes: the double-edged swords in tuberculosis
IFN γ-producing CD4+ T cells (IFNγ+CD4+ T cells) are the key orchestrators of protective immunity against Mycobacterium tuberculosis (Mtb). Primarily, these cells act by enabling Mtb-infected macrophages to enforc... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - June 15, 2017 Category: Internal Medicine Authors: Pawan Kumar Source Type: research

Single-cell RNA-sequencing of the brain
Single-cell RNA-sequencing (scRNA-seq) is revolutionizing our understanding of the genomic, transcriptomic and epigenomic landscapes of cells within organs. The mammalian brain is composed of a complex network... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - June 8, 2017 Category: Internal Medicine Authors: Raquel Cuevas-Diaz Duran, Haichao Wei and Jia Qian Wu Source Type: research