Clinical and Translational Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Evaluation of patients with multiple sclerosis using reverse nutech functional score and expanded disability status scale after human embryonic stem cell therapy
The expanded disability status scale (EDSS) is a validated and reliable tool to assess the extent of disabilities in patients with multiple sclerosis (MS). However, the use of this tool has been found to be li... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - October 20, 2016 Category: Internal Medicine Authors: Geeta Shroff Source Type: research

Serum levels of S100A6 are unaltered in patients with resectable cholangiocarcinoma
Elevated expression levels of S100A6, a calcium-binding low-molecular-weight protein, were demonstrated in various malignancies. Moreover, increased serum levels of S100A6 were suggested as a novel biomarker f... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - September 27, 2016 Category: Internal Medicine Authors: Sven H. Loosen, Fabian Benz, Jennifer Niedeggen, Maximilian Schmeding, Florian Sch üller, Alexander Koch, Mihael Vucur, Frank Tacke, Christian Trautwein, Christoph Roderburg, Ulf P. Neumann and Tom Luedde Source Type: research

Adult pulmonary tuberculosis as a pathological manifestation of hyperactive antimycobacterial immune response
The intricate relationship between tuberculosis (TB) and immune system remains poorly understood. It is generally believed that weakening of the immune response against Mycobacterium tuberculosis leads to reactiv... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - September 21, 2016 Category: Internal Medicine Authors: Pawan Kumar Source Type: research

Pharmacokinetics of oseltamivir in infants under the age of 1 year
Oseltamivir is the only antiviral treatment recommended for influenza in young children over the age of 1  year. There is scant data on oseltamivir pharmacokinetics (PK) in infants (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - September 5, 2016 Category: Internal Medicine Authors: Rashmi Dixit, Slade Matthews, Gulam Khandaker, Karen Walker, Marino Festa and Robert Booy Source Type: research

JNK inhibition reduces lung remodeling and pulmonary fibrotic systemic markers
Lung remodeling and pulmonary fibrosis are serious, life-threatening conditions resulting from diseases such as chronic severe asthma and idiopathic pulmonary fibrosis (IPF). Preclinical evidence suggests that... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - September 2, 2016 Category: Internal Medicine Authors: Jos L. J. van der Velden, Ying Ye, James D. Nolin, Sidra M. Hoffman, David G. Chapman, Karolyn G. Lahue, Sarah Abdalla, Peng Chen, Yong Liu, Brydon Bennett, Nasreen Khalil, Donna Sutherland, William Smith, Gerald Horan, Mahmoud Assaf, Zebulun Horowitz & h Source Type: research

A One Health overview, facilitating advances in comparative medicine and translational research
A1 One health advances and successes in comparative medicine and translational research (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 23, 2016 Category: Internal Medicine Authors: Cheryl Stroud, Igor Dmitriev, Elena Kashentseva, Jeffrey N. Bryan, David T. Curiel, Hans Rindt, Carol Reinero, Carolyn J. Henry, Philip J. Bergman, Nicola J. Mason, Josephine S. Gnanandarajah, Julie B. Engiles, Falon Gray, Danielle Laughlin, Anita Gaurnie Source Type: research

Is cancer a severe delayed hypersensitivity reaction and histamine a blueprint?
Longevity and accumulation of multiple context-dependent signaling pathways of long-standing inflammation (antigen-load or oxidative stress) are the results of decreased/altered regulation of immunity and loss... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 23, 2016 Category: Internal Medicine Authors: Mahin Khatami Source Type: research

Novel paradigm for immunotherapy of breast cancer by engaging prophylactic immunity against hepatitis B
Immunotherapy of patients suffering from the human epidermal growth factor receptor 2 overexpressing (HER-2+) breast cancers with the anti-HER-2 antibodies results in increase of the patients ’ overall survival. H... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 18, 2016 Category: Internal Medicine Authors: Marek Malecki, Chelsea Sabo, Afsoon Foorohar and Xenia Tombokan Source Type: research

Therapeutic use of stem cells for cardiovascular disease
Stem cell treatments are a desirable therapeutic option to regenerate myocardium and improve cardiac function after myocardial infarction. Several different types of cells have been explored, each with their o... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 18, 2016 Category: Internal Medicine Authors: Whitney Faiella and Rony Atoui Source Type: research

A quantitative metabolomics profiling approach for the noninvasive assessment of liver histology in patients with chronic hepatitis C
High-throughput technologies have the potential to identify non-invasive biomarkers of liver pathology and improve our understanding of basic mechanisms of liver injury and repair. A metabolite profiling appro... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 18, 2016 Category: Internal Medicine Authors: M. Omair Sarfaraz, Robert P. Myers, Carla S. Coffin, Zu-Hua Gao, Abdel Aziz M. Shaheen, Pam M. Crotty, Ping Zhang, Hans J. Vogel and Aalim M. Weljie Source Type: research

Creatine kinase in ischemic and inflammatory disorders
The creatine/phosphocreatine pathway plays a conserved and central role in energy metabolism. Compartmentalization of specific creatine kinase enzymes permits buffering of local high energy phosphates in a the... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 15, 2016 Category: Internal Medicine Authors: David Kitzenberg, Sean P. Colgan and Louise E. Glover Source Type: research

Erratum to: Clinical trial considerations on male contraception and  collection of pregnancy information from female partner: update
(Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 12, 2016 Category: Internal Medicine Authors: Maria Longauer Banholzer, Christoph Wandel, Paul Barrow, Marie Mannino, Georg Schmitt, Melanie Gu érard, Lutz Müller, Gerard Greig, Kenjie Amemiya, Richard Peck, Thomas Singer and Lucette Doessegger Source Type: research

Clinical significance of T cell metabolic reprogramming in cancer
Conversion of normal cells to cancer is accompanied with changes in their metabolism. During this conversion, cell metabolism undergoes a shift from oxidative phosphorylation to aerobic glycolysis, also known ... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 10, 2016 Category: Internal Medicine Authors: Christoph Herbel, Nikolaos Patsoukis, Kankana Bardhan, Pankaj Seth, Jessica D. Weaver and Vassiliki A. Boussiotis Source Type: research

Does it make sense to target one tumor cell chemotactic factor or its receptor when several chemotactic axes are involved in metastasis of the same cancer?
The major problem with cancer progression and anti-cancer therapy is the inherent ability of cancer cells to migrate and establish distant metastases. This ability to metastasize correlates with the presence i... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 10, 2016 Category: Internal Medicine Authors: Mariusz Z. Ratajczak, Malwina Suszynska and Magda Kucia Source Type: research

Therapeutic potential of mesenchymal stem cell based therapy for osteoarthritis
Osteoarthritis (OA) is a chronic degenerative disease affecting articular cartilage in joints, and it is a leading cause of disability in the United States. Current pharmacological treatment strategies are ine... (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - August 10, 2016 Category: Internal Medicine Authors: John Burke, Monte Hunter, Ravindra Kolhe, Carlos Isales, Mark Hamrick and Sadanand Fulzele Source Type: research