Early nonreactivity in the conjunctival provocation test predicts beneficial outcome of sublingual immunotherapy
ConclusionsUsing clinically meaningful outcome parameters during the pollen season, both trials independently led to similar results when comparing participants ’ reactions to the CPT 4 weeks after beginning SLIT. These results suggest that CPT allows an early estimation of allergic rhinoconjunctivitis symptoms before an upcoming season. Thus, the CPT can be used as a valuable parameter to predict the beneficial outcome of ongoing SLIT.Trial registrationBoth trials registered with the Medical Ethics Committee of the North Rhine Medical Council (EudraCT numbers 2012-004916-79 (grass pollen trial) and 2013-002129-43 (tree...
Source: Clinical and Translational Allergy - July 4, 2018 Category: Allergy & Immunology Source Type: research
Sinus computed tomography predicts clinical response to corticosteroids in chronic rhinosinusitis with nasal polyps
ConclusionOur prospective findings validate the potential value of sinus CT scan in predicting GC-sensitivity in CRSwNP patients. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - July 2, 2018 Category: Allergy & Immunology Source Type: research
Rapid onset of action and reduced nasal hyperreactivity: new targets in allergic rhinitis management
ConclusionWith the most rapid onset of action and onset of clinically-relevant effect of any AR medication currently available, and proven efficacy in the treatment of NHR, MP-AzeFlu is an AR treatment which provides what patients want, and fits how patients manage their AR in real life. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - June 25, 2018 Category: Allergy & Immunology Source Type: research
5th Pediatric Allergy and Asthma Meeting (PAAM)
(Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - June 25, 2018 Category: Allergy & Immunology Source Type: research
Rapid onset of action and reduced nasal hyperreactivity: new targets in allergic rhinitis management
ConclusionWith the most rapid onset of action and onset of clinically-relevant effect of any AR medication currently available, and proven efficacy in the treatment of NHR, MP-AzeFlu is an AR treatment which provides what patients want, and fits how patients manage their AR in real life. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - June 25, 2018 Category: Allergy & Immunology Source Type: research
Epidemiology of spider mite sensitivity: a meta-analysis and systematic review
ConclusionsSpider mites are an important cause of allergic symptoms. However, the publication bias and heterogeneity evident in this study indicate that further trials using standardized detection methods are needed to determine the association of exposure and symptoms as well as the specific patient characteristics that influence developing spider mite sensitivity. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - June 18, 2018 Category: Allergy & Immunology Source Type: research
Cross-sectional study on sensitization to mite and cockroach allergen components in allergy patients in the Central European region
ConclusionsThe majority of patients are co-sensitized to several molecules of the respective allergen source. The knowledge of this molecular spectrum of sensitization is important for optimal diagnosis and treatment in respect to allergen content in mite extracts used for diagnostic and therapeutic purposes. In regard to the sensitization patterns of Central European patients, it is necessary to point out the importance of quantifying at least three major mite components Der f 1, Der p 1 and Der f 2 (or Der p 2). (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - June 4, 2018 Category: Allergy & Immunology Source Type: research
The impact of cold on the respiratory tract and its consequences to respiratory health
AbstractThe increasing use, and sometimes the abuse, particularly in industrialized countries of air conditioning at home, in car, hotel and shopping centres has highlighted new emerging public health issues, resulting from exposure of the airways to cool air or, more properly, resulting from sudden temperature changes. This is part of a wider problem, relating to air quality in indoor environment, such as homes or offices, where people spend more than 90% of their time. In particular, if indoor exposure occurs quickly and without any gradual adaptation to a temperature 2 °–3° lower than the external temperature and es...
Source: Clinical and Translational Allergy - May 30, 2018 Category: Allergy & Immunology Source Type: research
