The impact of the elimination diet on growth and nutrient intake in children with food protein induced gastrointestinal allergies
Conclusion
With appropriate dietary advice, including optimal energy and protein intake, hypoallergenic formulas and vitamins and mineral supplementation, growth parameters increased from before to after dietary elimination. These factors were positively associated with growth, irrespective of the type of elimination diet and the numbers of foods eliminated. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - July 13, 2016 Category: Allergy & Immunology Source Type: research
Allergen immunotherapy for IgE-mediated food allergy: protocol for a systematic review
Discussion
The findings from this review will be used to inform the development of recommendations for EAACI’s Guidelines on AIT. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - July 4, 2016 Category: Allergy & Immunology Source Type: research
Influence of profilin on sensitisation profiles determined by cutaneous tests and IgE to major allergens in polysensitised patients
Conclusions
In patients sensitised to profilin, the concordance between SPT and CRD is much lower than in those not sensitised to profilin. CRD is able to provide refined information about which pollens increase the risk of sensitisation to profilin. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - June 28, 2016 Category: Allergy & Immunology Source Type: research
Very low prevalence of IgE mediated wheat allergy and high levels of cross-sensitisation between grass and wheat in a UK birth cohort
Conclusion
Clinicians should be aware of the high level of cross-sensitization when performing tests to wheat and grass pollen i.e. sensitisation to wheat specific IgE and wheat pollen SPT should be assessed in the presence of grass pollen SPT and/or specific IgE. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - June 21, 2016 Category: Allergy & Immunology Source Type: research
Current challenges facing the assessment of the allergenic capacity of food allergens in animal models
Abstract
Food allergy is a major health problem of increasing concern. The insufficiency of protein sources for human nutrition in a world with a growing population is also a significant problem. The introduction of new protein sources into the diet, such as newly developed innovative foods or foods produced using new technologies and production processes, insects, algae, duckweed, or agricultural products from third countries, creates the opportunity for development of new food allergies, and this in turn has driven the need to develop test methods capable of characterizing the allergenic potential of ...
Source: Clinical and Translational Allergy - June 15, 2016 Category: Allergy & Immunology Source Type: research
Nutritional adequacy of a cows ’ milk exclusion diet in infancy
Conclusion < /h3 > < p class= " a-plus-plus " > This study demonstrated that although infants consuming a milk-free diet have a nutritional intake that is significantly different to matched controls who are eating an unrestricted diet, this difference is not constant and it is not seen for all nutrients. Further research in infants without dietetic input is needed to explore the nutritional implications of unsupervised cows ’ milk exclusion diets. < /p > < /span > (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - June 1, 2016 Category: Allergy & Immunology Source Type: research
Nutritional adequacy of a cows’ milk exclusion diet in infancy
Conclusion
This study demonstrated that although infants consuming a milk-free diet have a nutritional intake that is significantly different to matched controls who are eating an unrestricted diet, this difference is not constant and it is not seen for all nutrients. Further research in infants without dietetic input is needed to explore the nutritional implications of unsupervised cows’ milk exclusion diets. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - June 1, 2016 Category: Allergy & Immunology Source Type: research
Intralymphatic immunotherapy induces allergen specific plasmablasts and increases tolerance to skin prick testing in a pilot study
Conclusions
This pilot study shows that ILIT may induce allergen specific plasmablasts, and confirms an effect on provocation of mast cells in skin and nasal mucosa during the ensuing winter. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - May 24, 2016 Category: Allergy & Immunology Source Type: research
Milk: a postnatal imprinting system stabilizing FoxP3 expression and regulatory T cell differentiation
Conclusion
Accumulating evidence underlines that milk is a complex signalling and epigenetic imprinting network that promotes stable FoxP3 expression and long-lasting Treg differentiation, crucial postnatal events preventing atopic and autoimmune diseases. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - May 11, 2016 Category: Allergy & Immunology Source Type: research
Cow ’s milk allergy in Dutch children: an epigenetic pilot survey
Conclusion < /h3 > < p class= " a-plus-plus " > We show that epigenetic associations are involved in CMA. Although, the statistical power of our study is limited and our sample was based on whole blood, we were still able to detect feasible loci and pathways. Therefore our findings might contribute to future diagnostic or therapeutic interventions for specific CMA. Further studies have to confirm the findings of our study. < /p > < /span > (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - May 3, 2016 Category: Allergy & Immunology Source Type: research
Cow’s milk allergy in Dutch children: an epigenetic pilot survey
Conclusion
We show that epigenetic associations are involved in CMA. Although, the statistical power of our study is limited and our sample was based on whole blood, we were still able to detect feasible loci and pathways. Therefore our findings might contribute to future diagnostic or therapeutic interventions for specific CMA. Further studies have to confirm the findings of our study. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - May 3, 2016 Category: Allergy & Immunology Source Type: research
Dietary intake and risk of asthma in children and adults: protocol for a systematic review and meta-analysis
Discussion
The findings from this review will be used as a reference to inform guideline recommendations. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - April 27, 2016 Category: Allergy & Immunology Source Type: research
Reviewer acknowledgement 2015
(Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - April 5, 2016 Category: Allergy & Immunology Source Type: research
Triclosan promotes epicutaneous sensitization to peanut in mice
Conclusions
Our results demonstrate that the mouse model of epicutaneous sensitization to foods is effective for demonstrating the clinically significant impact of environmental factors such as triclosan on food allergy. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - April 4, 2016 Category: Allergy & Immunology Source Type: research
Common environmental chemicals do not explain atopy contrast in the Finnish and Russian Karelia
Conclusions
Higher concentrations of common environmental chemicals were measured in Russian compared with Finnish Karelian children and mothers. The chemicals did not explain the higher prevalence of atopy on the Finnish side. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - April 3, 2016 Category: Allergy & Immunology Source Type: research
