Visual analogue scale for sino-nasal symptoms severity correlates with sino-nasal outcome test 22: paving the way for a simple outcome tool of CRS burden
ConclusionsVAS for total sino-nasal symptom severity might be used for assessing disease severity, monitoring the course of the disease, and can be used for treatment decisions and disease burden. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - September 3, 2018 Category: Allergy & Immunology Source Type: research
Abstracts from the 8th Drug Hypersensitivity Meeting (DHM)
(Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - August 21, 2018 Category: Allergy & Immunology Source Type: research
Promoting and achieving excellence in the delivery of Integrated Allergy Care: the European Academy of Allergy & amp; Clinical Immunology competencies for allied health professionals working in allergy
AbstractThe multi-disciplinary team approach is an effective model for patient care. Allied health professionals (AHPs) are an important part of such teams, bringing specific knowledge and skills related to the target patient population. The AHPs most often involved in allergy care are nurses and dietitians. Nurses are often involved in the care of patients with all types of allergy and also with asthma, whilst allergy-specialist dietitians provide vital nutritional and dietary support for the diagnosis and management of food allergy. There are many other AHPs who have a role to play in allergy care, including physiotherap...
Source: Clinical and Translational Allergy - August 21, 2018 Category: Allergy & Immunology Source Type: research
Abstracts from the 8th Drug Hypersensitivity Meeting (DHM)
(Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - August 21, 2018 Category: Allergy & Immunology Source Type: research
Promoting and achieving excellence in the delivery of Integrated Allergy Care: the European Academy of Allergy & amp; Clinical Immunology competencies for allied health professionals working in allergy
AbstractThe multi-disciplinary team approach is an effective model for patient care. Allied health professionals (AHPs) are an important part of such teams, bringing specific knowledge and skills related to the target patient population. The AHPs most often involved in allergy care are nurses and dietitians. Nurses are often involved in the care of patients with all types of allergy and also with asthma, whilst allergy-specialist dietitians provide vital nutritional and dietary support for the diagnosis and management of food allergy. There are many other AHPs who have a role to play in allergy care, including physiotherap...
Source: Clinical and Translational Allergy - August 21, 2018 Category: Allergy & Immunology Source Type: research
Maternal exposure to farming environment protects offspring against allergic diseases by modulating the neonatal TLR-Tregs-Th axis
ConclusionsMaternal exposure to farming affected the quantity and function of neonatal Tregs upon stimulation with PPG and LPS, which partly contributed to reducing the risk for allergic diseases in the offspring. The results of our study will lay the theoretical foundation for allergic disease prevention in early life. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - August 17, 2018 Category: Allergy & Immunology Source Type: research
Protease resistance of food proteins: a mixed picture for predicting allergenicity but a useful tool for assessing exposure
ConclusionsSub-optimal pH, low pepsin-to protein ratio, and sequential pepsin and pancreatin digestion protocols do not improve the predictive value in distinguish allergens from non-allergens. Digestion conditions facilitating such distinction differ per protein pair. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - August 10, 2018 Category: Allergy & Immunology Source Type: research
Assessing severity of anaphylaxis: a data-driven comparison of 23 instruments
ConclusionThe distributions of severity differed between the 23 instruments in both food and drug allergy, and thus rendering translation especially between scoring systems with 3 and 5 grades difficult. Fine-graded and simple instruments are preferred for comparison especially among milder reactions, and instruments applied to non-intended situations may not reflect a true severity picture. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - August 1, 2018 Category: Allergy & Immunology Source Type: research
Anti-IgE therapy for IgE-mediated allergic diseases: from neutralizing IgE antibodies to eliminating IgE + B cells
AbstractAllergic diseases are inflammatory disorders that involve many types of cells and factors, including allergens, immunoglobulin (Ig)E, mast cells, basophils, cytokines and soluble mediators. Among them, IgE plays a vital role in the development of acute allergic reactions and chronic inflammatory allergic diseases, making its control particularly important in the treatment of IgE-mediated allergic diseases. This review provides an overview of the current state of IgE targeted therapy development, focusing on three areas of translational research: IgE neutralization in blood; IgE-effector cell elimination; and IgE+ B...
Source: Clinical and Translational Allergy - July 18, 2018 Category: Allergy & Immunology Source Type: research
Severity of allergic rhinitis impacts sleep and anxiety: results from a large Spanish cohort
ConclusionsAlthough AR symptoms have a great impact on depression and anxiety symptoms, quality of life and quality of sleep in all AR patients, as expected, individuals with more severe AR seem to suffer more intensely their effects. (Source: Clinical and Translational Allergy)
Source: Clinical and Translational Allergy - July 9, 2018 Category: Allergy & Immunology Source Type: research
