Susceptible genes of restless legs syndrome in migraine
Conclusions
MEIS1 variants were associated with an increased risk of RLS in migraine patients. It is possible that an imbalance in iron homeostasis and the dopaminergic system may represent a link between RLS incidence and migraines. (Source: Cephalalgia)
Source: Cephalalgia - October 6, 2016 Category: Neurology Authors: Fuh, J.-L., Chung, M.-Y., Yao, S.-C., Chen, P.-K., Liao, Y.-C., Hsu, C.-L., Wang, P.-J., Wang, Y.-F., Chen, S.-P., Fann, C. S.-J., Kao, L.-S., Wang, S.-J. Tags: Original Articles Source Type: research
Screen time exposure and reporting of headaches in young adults: A cross-sectional study
Conclusion
High levels of screen time exposure are associated with migraine in young adults. No significant association was found with non-migraine headache. (Source: Cephalalgia)
Source: Cephalalgia - October 6, 2016 Category: Neurology Authors: Montagni, I., Guichard, E., Carpenet, C., Tzourio, C., Kurth, T. Tags: Original Articles Source Type: research
Headaches in patients with previous head injuries: A population-based historical cohort study (HUNT)
Conclusion
Headache was more likely among individuals previously referred to a hospital for a mild head injury compared to uninjured controls. (Source: Cephalalgia)
Source: Cephalalgia - October 6, 2016 Category: Neurology Authors: Hoem Nordhaug, L., Vik, A., Hagen, K., Stovner, L. J., Pedersen, T., Gravdahl, G. B., Linde, M. Tags: Original Articles Source Type: research
SUNCT syndrome: A cohort of 15 Portuguese patients
Conclusion
Our case series is among the largest reported, with findings similar to others already published, but the first to report epistaxis during SUNCT attack and response to eslicarbazepine. (Source: Cephalalgia)
Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Cacao, G., Correia, F. D., Pereira-Monteiro, J. Tags: Brief Reports Source Type: research
Late onset aura may herald cerebral amyloid angiopathy: A case report
Conclusion
In patients with a late onset of migraine aura, doctors must consider other under-recognized causes of transient neurological symptoms, such as cerebral amyloid angiopathy. Blood-sensitive magnetic resonance imaging sequences are the best tool for the early detection of an underlying pathology and therefore treatment with antiplatelet/anticoagulant drugs should be avoided as this may increase the risk of haemorrhage. (Source: Cephalalgia)
Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Samanci, B., Coban, O., Baykan, B. Tags: Brief Reports Source Type: research
Familial SUNCT in mother and son
We report on a mother and son with episodic, short-lasting, intense, paroxysmal headaches, with the same localization in the left retroauricular region, associated with prominent conjunctival injection and tearing, which are consistent with the diagnosis of SUNCT (short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing).
Discussion
These cases corroborate the existence of hereditary forms of this disorder, thus supporting its primary nature. (Source: Cephalalgia)
Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Martins, I. P., Viana, P., Lobo, P. P. Tags: Brief Reports Source Type: research
New daily persistent headache: A lack of an association with white matter abnormalities on neuroimaging
Conclusion
White matter abnormalities and infarct-like lesions do not appear to occur in primary new daily persistent headache patients. Only new daily persistent headache patients with risk factors (cardiovascular/cerebrovascular or migraine) developed white matter abnormalities on brain magnetic resonance imaging. No patient with new daily persistent headache developed infarct-like lesions. New daily persistent headache triggering events (outside of possibly post-surgery) or the presence of migrainous symptoms did not appear to enhance the development of white matter abnormalities. (Source: Cephalalgia)
Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Rozen, T. D. Tags: Brief Reports Source Type: research
Abdominal migraine
Conclusion
The recognition of AM by the IHS and the Rome Foundation should help facilitate future research into the pathophysiology of this debilitating condition and as a result better treatments for AM should emerge. Randomised controlled trials should be a priority. (Source: Cephalalgia)
Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Napthali, K., Koloski, N., Talley, N. J. Tags: Review Articles Source Type: research
A review of the current and potential oxygen delivery systems and techniques utilized in cluster headache attacks
Conclusions and implications
Interfaces like demand valves and tusk masks are already proving to be superior or at least similar to the standard NRM in terms of fraction of inspired oxygen (FiO2), though the demand valve only showed better results than the NRM in a single study in only four participants. Furthermore, new research shows how lower temperatures of the gas may be an essential part of effective pain relief and hyperbaric treatments show potential in preventing night time attacks. (Source: Cephalalgia)
Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Oude Nijhuis, J. C., Haane, D. Y., Koehler, P. J. Tags: Review Articles Source Type: research
General lack of use of placebo in prophylactic, randomised, controlled trials in adult migraine. A systematic review
Conclusions
The majority of comparative, prophylactic migraine RCTs do not include a placebo arm. Failure to include a placebo arm may result in failure to demonstrate efficacy of potentially effective migraine-prophylactic agents. In order to benefit current and future patients, the current strong tendency to omit placebo-controls in these RCTs should be replaced by adherence to the guidelines of the IHS. (Source: Cephalalgia)
Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Hougaard, A., Tfelt-Hansen, P. Tags: Review Articles Source Type: research
Premonitory symptoms in migraine: A cross-sectional study in 2714 persons
Conclusion
PS are experienced by a majority of migraineurs. More severe migraine is associated with a higher burden of PS. Since the material was not entirely representative of the general population of migraineurs, caution should be exercised in generalizing the results. (Source: Cephalalgia)
Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Laurell, K., Artto, V., Bendtsen, L., Hagen, K., Häggström, J., Linde, M., Söderström, L., Tronvik, E., Wessman, M., Zwart, J. A., Kallela, M. Tags: Original Articles Source Type: research
Oxytocin receptor: Expression in the trigeminal nociceptive system and potential role in the treatment of headache disorders
Conclusion
Oxytocin receptor expression in calcitonin gene-related peptide containing trigeminal ganglion neurons, and the blockade of calcitonin gene-related peptide release from trigeminal dural afferents suggests that activation of these receptors may provide therapeutic benefit in patients with migraine and other primary headache disorders. (Source: Cephalalgia)
Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Tzabazis, A., Mechanic, J., Miller, J., Klukinov, M., Pascual, C., Manering, N., Carson, D. S., Jacobs, A., Qiao, Y., Cuellar, J., Frey, W. H., Jacobs, D., Angst, M., Yeomans, D. C. Tags: Original Articles Source Type: research
Food insecurity and migraine in Canada
Conclusions
Food insecurity is more frequent among individuals reporting migraine in Canada. (Source: Cephalalgia)
Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Dooley, J. M., Gordon, K. E., Kuhle, S. Tags: Original Articles Source Type: research
sec-Butylpropylacetamide (SPD) has antimigraine properties
Conclusions
These results demonstrate SPD’s potential as a promising novel antimigraine compound, and suggest a GABAergic mechanism of action. (Source: Cephalalgia)
Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Kaufmann, D., Bates, E. A., Yagen, B., Bialer, M., Saunders, G. H., Wilcox, K., White, H. S., Brennan, K. Tags: Original Articles Source Type: research
Responses of dural mast cells in concussive and blast models of mild traumatic brain injury in mice: Potential implications for post-traumatic headache
Conclusions
mTBI evoked by closed head injury or blast exposure is associated with persistent dural MC degranulation. Such a response in mTBI patients may contribute to PTH. Amelioration of PTH by sumatriptan may not involve inhibition of dural MC degranulation. If persistent dural MC degranulation contributes to PTH, then cromolyn treatment may not be effective. (Source: Cephalalgia)
Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Levy, D., Edut, S., Baraz-Goldstein, R., Rubovitch, V., Defrin, R., Bree, D., Gariepy, H., Zhao, J., Pick, C. G. Tags: Original Articles Source Type: research
