Syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis (HaNDL): A case report with serial electroencephalography (EEG) recordings.. Is there an association with human herpes virus type 7 (HHV-7) infection?
We present a case of a 23-year-old woman with several episodes of transient headache, neurological deficits and cerebrospinal fluid lymphocytosis. All diagnostic criteria for the HaNDL syndrome were fulfilled; however, additional cerebrospinal fluid analysis showed a positive polymerase chain reaction (PCR) for human herpes virus type 7 (HHV-7). Discussion The possible role of a (prodromal) viral infection in the etiology of HaNDL is discussed. Also the role of electroencephalography (EEG) recordings is discussed. Serial EEG recordings showed generalized slowing, frontal intermittent rhythmic delta activity (FIRDA) and sy...
Source: Cephalalgia - November 8, 2016 Category: Neurology Authors: Stelten, B. M., Venhovens, J., van der Velden, L. B., Meulstee, J., Verhagen, W. I. Tags: October 2016 36 (12) Clinical Correspondence Source Type: research

The utility of radioisotope cisternography in low CSF/volume syndromes compared to myelography
Conclusion RC is comparable to CT myelography but has spatial limitations and should be limited to atypical cases. (Source: Cephalalgia)
Source: Cephalalgia - November 8, 2016 Category: Neurology Authors: Monteith, T. S., Kralik, S. F., Dillon, W. P., Hawkins, R. A., Goadsby, P. J. Tags: November 2016 36 (13) Brief Report Source Type: research

Laboratory tests of headache disorders - dawn of a new era?
Context The classification of headache disorders has improved over the years, but further work is needed to develop and improve headache diagnosis within headache subtypes. The present review is a call for action to implement laboratory tests in the classification and management of primary and some secondary headaches. Background In this narrative review we present and discuss published tests that might be useful in phenotyping and/or diagnosis of long-lasting headache disorders such as migraine, tension-type headache, trigeminal autonomic cephalalgias, trigeminal neuralgia and persisting secondary headaches. Aim The pal...
Source: Cephalalgia - November 8, 2016 Category: Neurology Authors: Schytz, H. W., Olesen, J. Tags: Review Articles Source Type: research

Spontaneous extracranial hemorrhagic phenomena in primary headache disorders: A systematic review of published cases
Conclusions Our results suggest that SEHP may be rare features of PHDs. Future studies would benefit from the systematic characterization of these phenomena. (Source: Cephalalgia)
Source: Cephalalgia - November 8, 2016 Category: Neurology Authors: Peretz, A. M., Woldeamanuel, Y. W., Rapoport, A. M., Cowan, R. P. Tags: November 2016 36 (13) Review Articles Source Type: research

Is palinopsia in migraineurs an enhanced physiological phenomenon?
Conclusion Migraineurs had a pattern of palinopsia to different colors that was similar to the controls, but the palinopsia of migraineurs was more frequent and of longer duration, especially during headaches. (Source: Cephalalgia)
Source: Cephalalgia - November 8, 2016 Category: Neurology Authors: Kalita, J., Uniyal, R., Bhoi, S. K. Tags: Original Articles Source Type: research

Early-onset familial hemiplegic migraine due to a novel SCN1A mutation
Introduction Familial hemiplegic migraine (FHM) is a rare autosomal dominant subtype of migraine with aura. The FHM3 subtype is caused by mutations in SCN1A, which is also the most frequent epilepsy gene encoding the voltage-gated Na+ channel NaV1.1. The aim of this study was to explore the clinical, genetic and pathogenetic features of a pure FHM3 family. Methods A three-generation family was enrolled in this study for genetic testing and assessment of clinical features. Whole cell patch-clamp was performed to determine the functions of identified mutant NaV1.1 channels, which were transiently expressed in human tsA201 c...
Source: Cephalalgia - November 8, 2016 Category: Neurology Authors: Fan, C., Wolking, S., Lehmann-Horn, F., Hedrich, U. B., Freilinger, T., Lerche, H., Borck, G., Kubisch, C., Jurkat-Rott, K. Tags: November 2016 36 (13) Original Articles Source Type: research

Ecological momentary assessment of the relationship between headache pain intensity and pain interference in women with migraine and obesity
Conclusions Pain intensity is a consistent predictor of pain interference on migraine headache days. Allodynia, PC, and HMSE moderated the pain intensity-interference relationship, and may be promising targets for interventions to reduce pain interference. (Source: Cephalalgia)
Source: Cephalalgia - November 8, 2016 Category: Neurology Authors: Thomas, J. G., Pavlovic, J., Lipton, R. B., Roth, J., Rathier, L., OLeary, K. C., Buse, D. C., Evans, E. W., Bond, D. S. Tags: Original Articles Source Type: research

Increased risk of trigeminal neuralgia in patients with migraine: A nationwide population-based study
Conclusions Migraine is a previously unidentified risk factor for trigeminal neuralgia. The association between these conditions suggests a linked underlying mechanism, which is worthy of further exploration. (Source: Cephalalgia)
Source: Cephalalgia - November 8, 2016 Category: Neurology Authors: Lin, K.-H., Chen, Y.-T., Fuh, J.-L., Wang, S.-J. Tags: November 2016 36 (13) Original Articles Source Type: research

How common is normal cerebrospinal fluid pressure in spontaneous intracranial hypotension?
Conclusions Normal CSF pressure is common in patients with SIH; the absence of a low opening pressure should not exclude this condition. Body habitus, symptom duration, and brain imaging are correlated with PCSF measurements, but these factors alone do not entirely explain the wide variability in observed pressures in this condition and this suggests the influence of other factors. (Source: Cephalalgia)
Source: Cephalalgia - November 8, 2016 Category: Neurology Authors: Kranz, P. G., Tanpitukpongse, T. P., Choudhury, K. R., Amrhein, T. J., Gray, L. Tags: Original Articles Source Type: research

Mindfulness and headache: A "new" old treatment, with new findings
Conclusions Much work remains to more fully document the role and long term value of mindfulness for specific headache types. Areas in need of further investigation are discussed. (Source: Cephalalgia)
Source: Cephalalgia - October 23, 2016 Category: Neurology Authors: Andrasik, F., Grazzi, L., D'Amico, D., Sansone, E., Leonardi, M., Raggi, A., Salgado-Garcia, F. Tags: Review Articles Source Type: research

Integrated multidisciplinary care of headache disorders: A narrative review
We present a narrative review reporting current literature and personal experience. Results and conclusion Based on current knowledge, multidisciplinary treatment programs appear to be reasonable and efficient in headache disorders. Sufficient controlled studies regarding the need for individual parts of the integrative care approach are missing as yet. Recommendations are therefore at least partly based on personal experiences. It seems to be unambiguous that patients should be referred to a specialized headache center offering such a program instead of being sent sequentially to various medical specialists. The extent a...
Source: Cephalalgia - October 23, 2016 Category: Neurology Authors: Gaul, C., Liesering-Latta, E., Schäfer, B., Fritsche, G., Holle, D. Tags: Review Articles Source Type: research

Noninvasive neurostimulation methods for migraine therapy: The available evidence
Conclusions The noninvasive neurostimulation methods are promising for migraine treatment and devoid of serious adverse effects allowing their combination with drug therapies. Their application in clinical practice will depend on the industry’s capacity to develop portable and user-friendly devices, and on the scientists’ capacity to prove their efficacy in randomized sham-controlled trials. (Source: Cephalalgia)
Source: Cephalalgia - October 23, 2016 Category: Neurology Authors: Schoenen, J., Roberta, B., Magis, D., Coppola, G. Tags: Review Articles Source Type: research

Invasive pericranial nerve interventions
Background In many patients suffering from primary headaches, the available pharmacological and behavioural treatments are not satisfactory. This is a review of (minimally) invasive interventions targeting pericranial nerves that could be effective in refractory patients. Methods The interventions we will cover have in common pericranial nerves as targets, but are distinct according to their rationale, modality and invasiveness. They range from nerve blocks/infiltrations to the percutaneous implantation of neurostimulators and surgical decompression procedures. We have critically analysed the published data (PubMed) on th...
Source: Cephalalgia - October 23, 2016 Category: Neurology Authors: Ambrosini, A., Schoenen, J. Tags: Review Articles Source Type: research

Sphenopalatine ganglion stimulation in cluster headache and other types of headache
Conclusions The reported studies have demonstrated that SPG stimulation is a safe and effective treatment for chronic cluster headache. Long-term studies have shown that the effect remains over time and this treatment could be a good choice in patients with chronic refractory headache. We need more data about its potential use in other forms of headache, such as other trigemino-autonomic headaches or migraine. (Source: Cephalalgia)
Source: Cephalalgia - October 23, 2016 Category: Neurology Authors: Lainez, M. J., Marti, A. S. Tags: Review Articles Source Type: research

Deep brain stimulation in headache
Conclusions: These observations need confirmation in randomised, controlled trials. A key role of the posterior hypothalamic area in the pathophysiology of unilateral short-lasting headaches, possibly by regulating the duration rather than triggering the attacks, can be hypothesised. Because of its invasiveness, hypothalamic stimulation can be proposed only after other, less-invasive, neurostimulation procedures have been tried. (Source: Cephalalgia)
Source: Cephalalgia - October 23, 2016 Category: Neurology Authors: Leone, M., Proietti Cecchini, A. Tags: Review Articles Source Type: research