Mechanisms of glyceryl trinitrate provoked mast cell degranulation
Conclusions
Direct application of an exogenous nitric oxide donor on dural mast cells does not cause mast cell degranulation ex vivo. In vivo application of the nitric oxide donor glyceryl trinitrate leads to a prominent level of degranulation via a yet unknown mechanism. This effect can be completely blocked by inhibition of the endogenous nitric oxide production and by 5-HT1B/1D receptor agonists but is unaffected by calcitonin gene-related peptide and substance P receptor antagonists. (Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Pedersen, S. H., Ramachandran, R., Amrutkar, D. V., Petersen, S., Olesen, J., Jansen-Olesen, I. Tags: Original Articles Source Type: research
White matter microstructure abnormalities in pediatric migraine patients
Conclusions
Pediatric migraine patients harbor diffuse brain WM microstructural abnormalities. High FA and low MD, AD and RD in these patients might be explained by repeated neuronal activation, which may lead to cell swelling and stimulate activity-dependent myelin-modulation, or by increased fiber and dendritic densities. Both these mechanisms might reflect a hyperexcitability of the brain in migraineurs. (Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Messina, R., Rocca, M. A., Colombo, B., Pagani, E., Falini, A., Comi, G., Filippi, M. Tags: Original Articles Source Type: research
Blunted autonomic response in cluster headache patients
Conclusions
CH patients show decreased autonomic response to HUT compared to healthy controls. This can be interpreted as dysregulation in the posterior hypothalamus and supports a theory of central autonomic mechanisms involvement in CH. (Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Barloese, M., Brinth, L., Mehlsen, J., Jennum, P., Lundberg, H. I. S., Jensen, R. Tags: Original Articles Source Type: research
Menstrual versus non-menstrual attacks of migraine without aura in women with and without menstrual migraine
Conclusion
In women from the general population, menstrual MO-attacks differ from non-menstrual attacks only in women who fulfil the ICHD criteria for MM. (Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Vetvik, K. G., Benth, J. S., MacGregor, E. A., Lundqvist, C., Russell, M. B. Tags: Original Articles Source Type: research
Is migraine a risk factor for pediatric stroke?
Conclusions
There was no statistically significant increase in hemorrhagic or ischemic stroke risk in pediatric migraineurs in this cohort study. A post-hoc analysis found that ischemic stroke risk was significantly elevated in adolescents with migraine. Future studies should focus on identifying risk factors for ischemic stroke among adolescent migraineurs. Based on adult data, we recommend that migraine aura status should be studied as a possible risk factor for ischemic stroke among adolescent migraineurs. (Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Gelfand, A. A., Fullerton, H. J., Jacobson, A., Sidney, S., Goadsby, P. J., Kurth, T., Pressman, A. Tags: December 2015 35 (14) Original Articles Source Type: research
Infantile colic associated with childhood migraine: A prospective cohort study
Discussion and conclusions
Infantile colic seems to be associated with an increased risk for migraine without aura, but not for migraine with aura. Whether infantile colic per se is a type of infantile migraine or an antecedent of future migraine remains to be answered by further research. (Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Sillanpää, M., Saarinen, M. Tags: December 2015 35 (14) Original Articles Source Type: research
Infant colic--a baby's migraine?
(Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Gelfand, A. A. Tags: Editorial Source Type: research
Letter from the Editor-in-Chief
(Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Dodick, D. W. Tags: Editorial Source Type: research
International Headache Congress 2015 late breaking abstracts (author index)
(Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Tags: Abstracts Source Type: research
International Headache Congress 2015 late breaking abstracts (posters)
(Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Tags: Abstracts Source Type: research
International Headache Congress 2015 late breaking abstracts (orals)
(Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Tags: Abstracts Source Type: research
Dr Ninan T Mathew--A tribute (1937-2015)
(Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Authors: Rapoport, A., Ravishankar, K. Tags: Letter to the Editor Source Type: research
Book review
(Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Authors: Moragas-Garrido, M. Tags: Book review Source Type: research
Huygens' headache
Conclusions
Although a posthumous diagnosis of Huygens' headaches is somewhat hazardous, the recurrent episodes with incapacitating headache and family history over two generations are suggestive for migraine. It becomes clear that it impeded his writing, reading, and research. From the letters we get an impression of the impact of the headache upon his life and the treatments that were applied in the 17th century. (Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Authors: Koehler, P. J. Tags: Historical Paper Source Type: research
Orthostatic headache from supratentorial meningioma
(Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Authors: Smith, R. M., Robertson, C. E., Garza, I. Tags: Imaging in Headache Medicine Source Type: research
