Treatment of hemicrania continua with radiofrequency ablation and long-term follow-up
Conclusion Hemicrania continua is defined by its sensitivity to indomethacin but very few patients are able to discontinue the medication without headache recurrence. As the risks of chronic indomethacin use are substantial, alternative treatments are necessary to protect patient health. We are now able to suggest several radiofrequency ablation procedures as effective as indomethacin with long-term follow-up. (Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Authors: Beams, J. L., Kline, M. T., Rozen, T. D. Tags: Clinical Correspondence Source Type: research

Infratrochlear neuralgia
Conclusion Infratrochlear neuralgia should be considered as a possible cause of pain in the internal angle of the orbit. (Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Authors: Pareja, J. A., Casanova, I., Arbex, A., Cuadrado, M. L. Tags: Original Articles Source Type: research

Sensitization of the trigeminovascular system following environmental irritant exposure
Background Air pollution is linked to increased emergency room visits for headache, and migraine patients frequently cite chemicals or odors as headache triggers, but the association between air pollutants and headache is not well understood. We previously reported that nasal administration of environmental irritants acutely increases meningeal blood flow via a TRPA1-dependent mechanism involving the trigeminovascular system. Here, we examine whether chronic environmental irritant exposure sensitizes the trigeminovascular system. Methods Male rats were exposed to acrolein, a TRPA1 agonist, or room air by inhalation for fo...
Source: Cephalalgia - November 4, 2015 Category: Neurology Authors: Kunkler, P. E., Zhang, L., Pellman, J. J., Oxford, G. S., Hurley, J. H. Tags: November 2015 35 (13) Original Articles Source Type: research

Prevalence and disability of headache among Norwegian adolescents: A cross-sectional school-based study
Conclusions Headaches are very common and disabling among adolescents. The full extent of this health problem is better appreciated if inquiry is not limited to the most bothersome subtypes. (Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Authors: Krogh, A.-B., Larsson, B., Linde, M. Tags: Original Articles Source Type: research

Triptans use and overuse: A pharmacoepidemiology study from the French health insurance system database covering 4.1 million people
Conclusions This work suggests that triptan overuse may be due to insufficient prescriber awareness of appropriate prescribing. The off-label prescription of triptans among the elderly necessitates investigating their cardiovascular risk profile in this sub-group. (Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Authors: Braunstein, D., Donnet, A., Pradel, V., Sciortino, V., Allaria-Lapierre, V., Lanteri-Minet, M., Micallef, J. Tags: Original Articles Source Type: research

Migraine affects white-matter tract integrity: A diffusion-tensor imaging study
Conclusion Results indicate that white-matter integrity is altered in migraine and that longer migraine history is positively correlated with greater alterations in tract integrity. (Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Authors: Chong, C. D., Schwedt, T. J. Tags: November 2015 35 (13) Original Articles Source Type: research

Oligoclonal bands and increased cytokine levels in idiopathic intracranial hypertension
Conclusion The presence of OCBs and elevated cytokine levels in IIH patients may support an immunologic background in the pathophysiological pathway of this disorder. (Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Authors: Altıokka-Uzun, G., Tüzün, E., Ekizoglu, E., Ulusoy, C., Yentür, S., Kürtüncü, M., Saruhan-Direskeneli, G., Baykan, B. Tags: November 2015 35 (13) Original Articles Source Type: research

Headache neuroimaging: Routine testing when guidelines recommend against them
Conclusions Neuroimaging is routinely ordered in outpatient headache patients including populations where guidelines specifically recommend against their use (migraines, chronic headaches, no red flags). (Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Authors: Callaghan, B. C., Kerber, K. A., Pace, R. J., Skolarus, L., Cooper, W., Burke, J. F. Tags: November 2015 35 (13) Original Articles Source Type: research

Neuroimaging in headache: Lessons not learned
(Source: Cephalalgia)
Source: Cephalalgia - November 4, 2015 Category: Neurology Authors: Frishberg, B. Tags: Editorial Source Type: research

Guidelines for controlled trials of drugs in tension‐type headache: second edition / Guidelines for controlled trials of drugs in tension‐type headache: second edition
The Clinical Trials Subcommittee of the International Headache Society published its first edition of the guidelines on controlled trials of drugs in tension‐type headache in 1995. These aimed ‘to improve the quality of controlled clinical trials in tension‐type headache’, because ‘good quality controlled trials are the only way to convincingly demonstrate the efficacy of a drug, and form the basis for international agreement on drug therapy’. The Committee published similar guidelines for clinical trials in migraine and cluster headache. Since 1995 several studies on the treatment of episodic and chronic tensi...
Source: Cephalalgia - July 13, 2009 Category: Neurology Authors: L Bendtsen, ME Bigal, R Cerbo, HC Diener, K Holroyd, C Lampl, DD Mitsikostas, TJ Steiner, P Tfelt‐Hansen Source Type: research