Evaluation of the new ICHD-III beta cluster headache criteria
Conclusion The results of this study do not support the addition of ear fullness and facial flushing to the new ICHD-III beta criteria. (Source: Cephalalgia)
Source: Cephalalgia - April 28, 2016 Category: Neurology Authors: de Coo, I., Wilbrink, L., Haan, J., Ferrari, M., Terwindt, G. Tags: Original Articles Source Type: research

Non-invasive vagus nerve stimulation for PREVention and Acute treatment of chronic cluster headache (PREVA): A randomised controlled study
Conclusion Adjunctive prophylactic nVNS is a well-tolerated novel treatment for chronic CH, offering clinical benefits beyond those with SoC. (Source: Cephalalgia)
Source: Cephalalgia - April 28, 2016 Category: Neurology Authors: Gaul, C., Diener, H.-C., Silver, N., Magis, D., Reuter, U., Andersson, A., Liebler, E. J., Straube, A., on behalf of the PREVA Study Group Tags: Original Articles Source Type: research

Interictal photosensitivity associates with altered brain structure in patients with episodic migraine
Conclusion Episodic migraineurs with interictal photosensitivity have greater cortical thickness in the right parietal-occipital and left fronto-parietal regions, suggesting that persistent light sensitivity is associated with underlying structural alterations. (Source: Cephalalgia)
Source: Cephalalgia - April 28, 2016 Category: Neurology Authors: Chong, C. D., Starling, A. J., Schwedt, T. J. Tags: Original Articles Source Type: research

Serum levels of pentraxin-3 and other inflammatory biomarkers in migraine: Association with migraine characteristics
Conclusions PTX-3 and fibrinogen exhibit different serum levels in patients undergoing a migraine attack compared with the interictal group and the controls. Participants with longer attacks and disease durations have lower serum levels of PTX-3, suggesting that inflammatory processes change along with disease progression. (Source: Cephalalgia)
Source: Cephalalgia - April 28, 2016 Category: Neurology Authors: Ceylan, M., Bayraktutan, O. F., Becel, S., Atis, O., Yalcin, A., Kotan, D. Tags: Original Articles Source Type: research

Epidemiological and clinical features of migraine in the pediatric population of Northern Italy
Conclusion We describe the characteristics of pediatric migraine based on the ICHD-II criteria, showing a likely significant loss of diagnoses using the ICHD-III beta. The incidence of migraine increases with age. MO occurs more commonly and shows more frequent attacks and a higher prevalence of associated symptoms, in particular osmophobia. Although males are prevalent in the entire sample, the proportion of females is higher among patients with MA in all of the age groups. Phenotype and sexual prevalence of migraine acquire adult characteristics and become more frequent in females from the onset of puberty. (Source: Cephalalgia)
Source: Cephalalgia - April 28, 2016 Category: Neurology Authors: Tarasco, V., Grasso, G., Versace, A., Castagno, E., Ricceri, F., Urbino, A., Pagliero, R. Tags: Original Articles Source Type: research

Pilot study of sphenopalatine injection of onabotulinumtoxinA for the treatment of intractable chronic cluster headache
Conclusion Randomised, placebo-controlled studies are warranted to establish the potential of this possible novel treatment of cluster headache. (Source: Cephalalgia)
Source: Cephalalgia - April 28, 2016 Category: Neurology Authors: Bratbak, D. F., Nordgard, S., Stovner, L. J., Linde, M., Folvik, M., Bugten, V., Tronvik, E. Tags: Original Articles Source Type: research

What triggers migraine aura?
(Source: Cephalalgia)
Source: Cephalalgia - April 28, 2016 Category: Neurology Authors: Diener, H.-C. Tags: Editorial Source Type: research

Factors associated with frovatriptan response in patients with migraine: A prospective, observational study
Conclusions Depression may be a risk factor of frovatriptan inefficacy in patients with migraine, even though half of patients with major depressive disorder respond to frovatriptan. (Source: Cephalalgia)
Source: Cephalalgia - April 20, 2016 Category: Neurology Authors: Seo, J.-G., Park, S.-P. Tags: Brief Report Source Type: research

Efficacy of interventions used by physiotherapists for patients with headache and migraine--systematic review and meta-analysis
Discussion Results suggest a statistically significant reduction in the intensity, frequency and duration of migraine, TTH and CGH. Pain reduction and reduction in CGH frequency do not reach clinically relevant effect sizes. Small sample sizes, inadequate use of headache classification, and other methodological shortcomings reduce the confidence in these results. Methodologically sound, randomized controlled trials with adequate sample sizes are required to provide information on whether and which physiotherapy approach is effective. According to Grading of Recommendations Assessment, Development and Evaluation (GRADE), th...
Source: Cephalalgia - April 20, 2016 Category: Neurology Authors: Luedtke, K., Allers, A., Schulte, L. H., May, A. Tags: Review Source Type: research

Laser-evoked potential habituation and central sensitization symptoms in childhood migraine
Discussion Abnormalities of pain processing and symptoms of central sensitization appear to be characteristics of children with migraine. Reduced habituation and progressive amplification of cortical responses to laser stimuli indicate an overactive nociceptive system at the onset of migraine, and this hyperactivity may subtend allodynia and pericranial tenderness. Future prospective trials may aid in the early identification of clinical phenotypes that display a tendency to develop into the chronic form of migraine, warranting a timely therapeutic approach. (Source: Cephalalgia)
Source: Cephalalgia - April 20, 2016 Category: Neurology Authors: de Tommaso, M., Sciruicchio, V., Ricci, K., Montemurno, A., Gentile, F., Vecchio, E., Barbaro, M. G. F., Simeoni, M., Goffredo, M., Livrea, P. Tags: Original Articles Source Type: research

Vestibular migraine in multicenter neurology clinics according to the appendix criteria in the third beta edition of the International Classification of Headache Disorders
Conclusion We diagnosed VM in 10.3% of first-visit migraineurs in neurology clinics using the ICHD-3β. Applying the diagnosis of probable VM can increase the identification of VM. (Source: Cephalalgia)
Source: Cephalalgia - April 20, 2016 Category: Neurology Authors: Cho, S.-J., Kim, B.-K., Kim, B.-S., Kim, J.-M., Kim, S.-K., Moon, H.-S., Song, T.-J., Cha, M.-J., Park, K.-Y., Sohn, J.-H. Tags: Original Articles Source Type: research

Peripheral nerve field stimulation for trigeminal neuralgia, trigeminal neuropathic pain, and persistent idiopathic facial pain
Conclusion PNFS may be an effective treatment for refractory facial pain and yields high patient satisfaction. (Source: Cephalalgia)
Source: Cephalalgia - April 20, 2016 Category: Neurology Authors: Klein, J., Sandi-Gahun, S., Schackert, G., Juratli, T. A. Tags: Original Articles Source Type: research

Headache and peak oxygen uptake: The HUNT3 study
Conclusions In this large cross-sectional study, an inverse relationship was found between VO2peak and headache for adults younger than 50 years of age. (Source: Cephalalgia)
Source: Cephalalgia - April 20, 2016 Category: Neurology Authors: Hagen, K., Wisloff, U., Ellingsen, O., Stovner, L. J., Linde, M. Tags: Original Articles Source Type: research

Bidirectional triggering association between migraine and restless legs syndrome: A diary study
Conclusions Our study results showed a bidirectional triggering association between migraine and RLS attacks. The association was stronger and lasted longer for migraine triggering subsequent RLS than that for vice versa. (Source: Cephalalgia)
Source: Cephalalgia - April 20, 2016 Category: Neurology Authors: Chen, P.-K., Fuh, J.-L., Wang, S.-J. Tags: Original Articles Source Type: research

The impact of cognitive symptoms on migraine attack-related disability
Conclusions Attack-related cognitive symptoms are intense and disabling. Some attack-related cognitive symptoms correlate to intensity and disability subjectively attributed to the migraine attack. Cognitive performance should be addressed as a valuable secondary endpoint in trials of acute migraine treatment. (Source: Cephalalgia)
Source: Cephalalgia - April 20, 2016 Category: Neurology Authors: Gil-Gouveia, R., Oliveira, A. G., Martins, I. P. Tags: Original Articles Source Type: research