Reduced functional connectivity between salience and visual networks in migraine with aura
Conclusions
The unique pattern of connectivity changes found in interictal MA patients involved area V3A, an area previously implicated in aura generation. Hypoconnectivity to this and other occipital regions may either represent a compensatory response to occipital dysfunctions or predispose MA patients to the development of aura. (Source: Cephalalgia)
Source: Cephalalgia - December 17, 2015 Category: Neurology Authors: Niddam, D. M., Lai, K.-L., Fuh, J.-L., Chuang, C.-Y. N., Chen, W.-T., Wang, S.-J. Tags: January 2016 36 (1), January 2016 36 (1) Original Articles Source Type: research
Temporal profiles of high-mobility group box 1 expression levels after cortical spreading depression in mice
Conclusion
Cortical spreading depression induced translocation of high-mobility group box 1 from neuronal nuclei, driving transcriptional up-regulation of high-mobility group box 1 to maintain protein levels. (Source: Cephalalgia)
Source: Cephalalgia - December 17, 2015 Category: Neurology Authors: Takizawa, T., Shibata, M., Kayama, Y., Toriumi, H., Ebine, T., Koh, A., Shimizu, T., Suzuki, N. Tags: January 2016 36 (1), January 2016 36 (1) Original Articles Source Type: research
Evaluation of interictal autonomic function during attack and remission periods in cluster headaches
Conclusion
Sympathetic hypoactivity of the face seems to predominate the pathophysiology of cluster headache. Face sympathetic skin responses might be more sensitive compared to extremity sympathetic skin response in demonstrating dysautonomic symptoms in cluster headache patients. (Source: Cephalalgia)
Source: Cephalalgia - December 17, 2015 Category: Neurology Authors: Altiokka, O., Mutluay, B., Koksal, A., Ciftci-Kavaklioglu, B., Ozturk, M., Altunkaynak, Y., Baybas, S., Soysal, A. Tags: January 2016 36 (1), January 2016 36 (1) Original Articles Source Type: research
Neck and shoulder muscle strength in patients with tension-type headache: A case-control study
Conclusion
Patients with TTH exhibited decreased muscle strength in the neck extensor muscles, inducing a reduced cervical extension/flexion ratio compared to healthy people. (Source: Cephalalgia)
Source: Cephalalgia - December 17, 2015 Category: Neurology Authors: Madsen, B. K., Sogaard, K., Andersen, L. L., Skotte, J. H., Jensen, R. H. Tags: Original Articles Source Type: research
Medication overuse, healthy lifestyle behaviour and stress in chronic headache: Results from a population-based representative survey
Conclusion
Results suggest strong links between healthy lifestyle behaviour and stress in MOH. Stress reduction and promoting healthy behaviour are highly relevant in MOH management. (Source: Cephalalgia)
Source: Cephalalgia - December 17, 2015 Category: Neurology Authors: Westergaard, M. L., Glümer, C., Hansen, E. H., Jensen, R. H. Tags: January 2016 36 (1), January 2016 36 (1) Original Articles Source Type: research
Abnormal inhibition-excitation imbalance in migraine
Conclusions
Supersaturation in migraine is consistent with excess excitation (hyperresponsivity) driving increased network inhibition and provides support for excitatory-inhibitory imbalance as a pathophysiological disturbance in migraine. (Source: Cephalalgia)
Source: Cephalalgia - December 17, 2015 Category: Neurology Authors: Nguyen, B. N., McKendrick, A. M., Vingrys, A. J. Tags: Original Articles Source Type: research
Letter from the Editor-in-Chief
(Source: Cephalalgia)
Source: Cephalalgia - December 17, 2015 Category: Neurology Authors: May, A. Tags: Editorial Source Type: research
Can 'migraine' be defined? - Yes and we have to
(Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Schulte, L., May, A. Tags: Letters to the Editor Source Type: research
Can migraine be defined?
(Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Lane, R., Davies, P. Tags: Letters to the Editor Source Type: research
What makes migraine a migraine - of the importance of disease classifications in scientific research
(Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Schulte, L., May, A. Tags: Letters to the Editor Source Type: research
Primary intracranial angiomatoid fibrous histiocytoma presenting with anaemia and migraine-like headaches and aura as early clinical features
A 17-year-old female with migraine with aura complained of fatigue and was diagnosed with anemia. Three years later, changes in her headache pattern prompted hospital referral. Brain MRI showed a bi-lobed extra-axial intracerebral tumor encroaching both parieto-occipital regions. The resection specimen yielded a rare diagnosis of primary intracranial angiomatoid fibrous histiocytoma (AFH). Tumor removal resulted in cessation of her migraine and anemia. AFH may cause systemic symptoms – in this case fatigue and anemia – long before focal neurological symptoms are present. This is the first report of an intracran...
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Hansen, J. M., Larsen, V. A., Scheie, D., Perry, A., Skjoth-Rasmussen, J. Tags: Imaging in Headache Medicine Source Type: research
Contrast-enhanced magnetic resonance imaging in carbamazepine-induced aseptic meningitis
(Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Kageyama, T., Isohisa, A., Mori, N., Suenaga, T. Tags: Imaging in Headache Medicine Source Type: research
Multimodal manual therapy vs. pharmacological care for management of tension type headache: A meta-analysis of randomized trials
Conclusion
Manual therapies were associated with moderate effectiveness at short term, but similar effectiveness at longer follow-up for reducing headache frequency, intensity and duration in tension type headache than pharmacological medical drug care. However, due to the heterogeneity of the interventions, these results should be considered with caution at this stage. (Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Mesa-Jimenez, J. A., Lozano-Lopez, C., Angulo-Diaz-Parreno, S., Rodriguez-Fernandez, A. L., De-la-Hoz-Aizpurua, J. L., Fernandez-de-las-Penas, C. Tags: Review Articles Source Type: research
Targeting pericranial nerve branches to treat migraine: Current approaches and perspectives
Conclusions
Although current knowledge on migraine pathophysiology suggests a central nervous system dysfunction, there is some evidence that interventions targeting peripheral nerves are able to modulate neuronal circuits involved in pain control and that they could be useful in some selected patients. Larger, well-designed and comparative trials are needed to appraise the respective advantages, disadvantages and indications of most interventions discussed here. (Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Ambrosini, A., D'Alessio, C., Magis, D., Schoenen, J. Tags: December 2015 35 (14) Review Articles Source Type: research
Periaqueductal gray calcitonin gene-related peptide modulates trigeminovascular neurons
Conclusions
CGRP and its receptor antagonists act on neurons in the region of vlPAG to influence nociceptive transmission in the TCC. This suggests CGRP receptor antagonists may act at loci outside of the TCC and reinforces the concept of migraine as a disorder of the brain. (Source: Cephalalgia)
Source: Cephalalgia - November 16, 2015 Category: Neurology Authors: Pozo-Rosich, P., Storer, R., Charbit, A., Goadsby, P. Tags: December 2015 35 (14) Original Articles Source Type: research