Food insecurity and migraine
(Source: Cephalalgia)
Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Rist, P., Kurth, T. Tags: Editorial Source Type: research
Reply to Dr. Merrys Letter to the Editor
(Source: Cephalalgia)
Source: Cephalalgia - July 21, 2016 Category: Neurology Authors: Dilli, E., Dodick, D. Tags: Letters to the Editor Source Type: research
Re: Occipital nerve block for the short-term prevention of migraine
(Source: Cephalalgia)
Source: Cephalalgia - July 21, 2016 Category: Neurology Authors: Merry, S. P. Tags: Letters to the Editor Source Type: research
OnabotulinumtoxinA improves quality of life and reduces impact of chronic migraine over one year of treatment: Pooled results from the PREEMPT randomized clinical trial program
Conclusions
Benefits of onabotulinumtoxinA on HRQoL versus baseline persisted throughout the OL phase. Statistical superiority in favor of O/O was demonstrated for HIT-6 through 48 weeks and for MSQ (role restrictive) at 56 weeks. (Source: Cephalalgia)
Source: Cephalalgia - July 21, 2016 Category: Neurology Authors: Lipton, R. B., Rosen, N. L., Ailani, J., DeGryse, R. E., Gillard, P. J., Varon, S. F. Tags: Original Articles Source Type: research
A phase IIb randomized, double-blind, placebo-controlled trial of ubrogepant for the acute treatment of migraine
Conclusion
This trial supports ubrogepant’s efficacy and provides further evidence that CGRP-RAs are viable options for the acute treatment of migraine. (Source: Cephalalgia)
Source: Cephalalgia - July 21, 2016 Category: Neurology Authors: Voss, T., Lipton, R. B., Dodick, D. W., Dupre, N., Ge, J. Y., Bachman, R., Assaid, C., Aurora, S. K., Michelson, D. Tags: Original Articles Source Type: research
Extracranial injections of botulinum neurotoxin type A inhibit intracranial meningeal nociceptors responses to stimulation of TRPV1 and TRPA1 channels: Are we getting closer to solving this puzzle?
This study demonstrates that extracranial administration of BoNT-A suppresses meningeal nociceptors’ responses to stimulation of their intracranial dural receptive fields with capsaicin and mustard oil. The findings suggest that surface expression of TRPV1 and TRPA1 channels in dural nerve endings of meningeal nociceptors is reduced seven days after extracranial administration of BoNT-A. In the context of chronic migraine, reduced sensitivity to molecules that activate meningeal nociceptors through the TRPV1 and TRPA1 channels can be important for BoNT-A’s ability to act as a prophylactic. (Source: Cephalalgia)
Source: Cephalalgia - July 21, 2016 Category: Neurology Authors: Zhang, X., Strassman, A. M., Novack, V., Brin, M. F., Burstein, R. Tags: Original Articles Source Type: research
Comparative effectiveness of onabotulinumtoxinA versus oral migraine prophylactic medications on headache-related resource utilization in the management of chronic migraine: Retrospective analysis of a US-based insurance claims database
Conclusions
When compared with similar patients who initiated treatment with OMPM, onabotulinumtoxinA was associated with a significantly lower likelihood of headache-related ED visits and hospitalizations. (Source: Cephalalgia)
Source: Cephalalgia - July 21, 2016 Category: Neurology Authors: Hepp, Z., Rosen, N. L., Gillard, P. G., Varon, S. F., Mathew, N., Dodick, D. W. Tags: Original Articles Source Type: research
The modulatory effect of anandamide on nitroglycerin-induced sensitization in the trigeminal system of the rat
Background
One of the human and animal models of migraine is the systemic administration of the nitric oxide donor (NO) nitroglycerin (NTG). NO can provoke migraine-like attacks in migraineurs and initiates a self-amplifying process in the trigeminal system, probably leading to central sensitization. Recent studies suggest that the endocannabinoid system is involved in nociceptive signal processing and cannabinoid receptor (CB) agonists are able to attenuate nociception in animal models of pain.
Aim
The purpose of the present study was to investigate the modulatory effects of a CB agonist anandamide (AEA) on the NTG-induc...
Source: Cephalalgia - July 21, 2016 Category: Neurology Authors: Nagy-Grocz, G., Tar, L., Bohar, Z., Fejes-Szabo, A., Laborc, K. F., Spekker, E., Vecsei, L., Pardutz, A. Tags: Original Articles Source Type: research
Migraine and subclinical atherosclerosis in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
Conclusions
In this cross-sectional evaluation of the ELSA study, migraine was not associated with subclinical atherosclerosis, regardless of aura symptoms. (Source: Cephalalgia)
Source: Cephalalgia - July 21, 2016 Category: Neurology Authors: Goulart, A. C., Santos, I. S., Bittencourt, M. S., Lotufo, P. A., Bensenor, I. M. Tags: Original Articles Source Type: research
Test-retest reliability of visual-evoked potential habituation
Conclusions
Deficient VEP habituation in migraine was confirmed. However, the test-retest reliability of VEP habituation was rather weak. Therefore, we suggest that VEP habituation should be used for evaluation of cortical excitability under treatment only at the group level and only when a control group with sham treatment is included. (Source: Cephalalgia)
Source: Cephalalgia - July 21, 2016 Category: Neurology Authors: Rauschel, V., Ruscheweyh, R., Krafczyk, S., Straube, A. Tags: Original Articles Source Type: research
Variability of the characteristics of a migraine attack within patients
Conclusion
Migraine attacks show a high variability not just among patients, but also within the same patient. Our data indicate that stereotypy of attacks is uncommon, and reinforces the underlying logic of the current operational classification system. (Source: Cephalalgia)
Source: Cephalalgia - July 21, 2016 Category: Neurology Authors: Viana, M., Sances, G., Ghiotto, N., Guaschino, E., Allena, M., Nappi, G., Goadsby, P., Tassorelli, C. Tags: Original Articles Source Type: research
Description of Master in Headache Disorders at The University of Copenhagen, Denmark
(Source: Cephalalgia)
Source: Cephalalgia - June 23, 2016 Category: Neurology Tags: Description of Master in Headache Disorders Source Type: research
Corrigendum
(Source: Cephalalgia)
Source: Cephalalgia - June 23, 2016 Category: Neurology Tags: Corrigendum Source Type: research
Board Walk July 2016
(Source: Cephalalgia)
Source: Cephalalgia - June 23, 2016 Category: Neurology Tags: Board Walk Source Type: research
Book review
(Source: Cephalalgia)
Source: Cephalalgia - June 23, 2016 Category: Neurology Authors: Silver, N. Tags: Book review Source Type: research
