Temporal profiles of high-mobility group box 1 expression levels after cortical spreading depression in mice

Conclusion
Cortical spreading depression induced translocation of high-mobility group box 1 from neuronal nuclei, driving transcriptional up-regulation of high-mobility group box 1 to maintain protein levels.

Source: Cephalalgia - December 17, 2015 Category: Neurology Authors: Takizawa, T., Shibata, M., Kayama, Y., Toriumi, H., Ebine, T., Koh, A., Shimizu, T., Suzuki, N. Tags: January 2016 36 (1), January 2016 36 (1) Original Articles Source Type: research