Oxytocin receptor: Expression in the trigeminal nociceptive system and potential role in the treatment of headache disorders

Conclusion
Oxytocin receptor expression in calcitonin gene-related peptide containing trigeminal ganglion neurons, and the blockade of calcitonin gene-related peptide release from trigeminal dural afferents suggests that activation of these receptors may provide therapeutic benefit in patients with migraine and other primary headache disorders.

Source: Cephalalgia - August 18, 2016 Category: Neurology Authors: Tzabazis, A., Mechanic, J., Miller, J., Klukinov, M., Pascual, C., Manering, N., Carson, D. S., Jacobs, A., Qiao, Y., Cuellar, J., Frey, W. H., Jacobs, D., Angst, M., Yeomans, D. C. Tags: Original Articles Source Type: research