Urologic Oncology: Seminars and Original Investigations This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A systematic review and meta-analysis of lymphovascular invasion in patients treated with radical cystectomy for bladder cancer
Lymphovascular invasion (LVI) is an important step in bladder cancer cell dissemination. We aimed to perform a systematic review and meta-analysis of the literature to assess the prognostic value of LVI in radical cystectomy (RC) specimens. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - April 20, 2018 Category: Urology & Nephrology Authors: Andrea Mari, Shoji Kimura, Beat Foerster, Mohammad Abufaraj, David D'Andrea, Kilian M. Gust, Shahrokh F. Shariat Tags: Review article Source Type: research

Nomograms are key decision-making tools in prostate cancer radiation therapy
The use of nomograms for predicting clinical endpoints has been well documented. Nomograms provide an individualized prognosis and help clinicians determine the effectiveness of treatment for a given patient. Early identification of potential treatment failure or toxicity allows alternative approaches to be considered, reducing unnecessary treatment, morbidity, and cost. This review aims to evaluate clinical potential of nomogram use for the management of prostate cancer radiotherapy patients. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - April 18, 2018 Category: Urology & Nephrology Authors: Sarah Caulfield, Gerard Menezes, Laure Marignol, Claire Poole Tags: Review article Source Type: research

Monopolar vs. bipolar transurethral resection for non –muscle invasive bladder carcinoma: A post-hoc analysis from a randomized controlled trial
In this study we compare safety and efficacy between monopolar TURB (mTURB) and bipolar TURB (bTURB) for patients with primary non-muscle invasive bladder cancer (NMIBC). (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - April 13, 2018 Category: Urology & Nephrology Authors: Esmee I.M.L. Liem, Michael McCormack, Eddie S.Y. Chan, Yoshiyuki Matsui, Petrisor Geavlete, Young D. Choi, Theo M. de Reijke, Yasser Farahat, Brant A. Inman, Jean J.M.C.H. de la Rosette, Seiji Naito Tags: Original article Source Type: research

Monocarboxylate transporters MCT1 and MCT4 are independent prognostic biomarkers for the survival of patients with clear cell renal cell carcinoma and those receiving therapy targeting angiogenesis
In this study, we examined the correlations of monocarboxylate transporter 1 (MCT1) and MCT4, 2 critical transporters for glycolytic metabolism, with various clinicopathological parameters as well as survival of patients with ccRCC and those treated with vascular endothelial growth factor receptor (VEGFR) inhibitors. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - April 12, 2018 Category: Urology & Nephrology Authors: Yan-Wei Cao, Yong Liu, Zhen Dong, Lei Guo, En-Hao Kang, Yong-Hua Wang, Wei Zhang, Hai-Tao Niu Tags: Original article Source Type: research

Mechanistic target of rapamycin (MTOR) protein expression in the tumor and its microenvironment correlates with more aggressive pathology at cystectomy
The mechanistic target of rapamycin (mTOR) has been implicated in driving tumor biology in multiple malignancies, including urothelial carcinoma (UC). We investigate how mTOR and phosphorylated mTOR (pmTOR) protein expression correlate with chemoresponsiveness in the tumor and its microenvironment at final pathologic staging after neoadjuvant chemotherapy (NAC). (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - April 12, 2018 Category: Urology & Nephrology Authors: Brian R. Winters, Funda Vakar-Lopez, Lisha Brown, Bruce Montgomery, Roland Seiler, Peter C. Black, Joost L. Boormans, Marc Dall ′Era, Elai Davincioni, James Douglas, Ewan A. Gibb, Bas W.G. van Rhijn, Michiel S. van der Heijden, Andrew C. Hsieh, Jonathan Tags: Original article Source Type: research

Stauffer ’s syndrome: A comprehensive review and proposed updated diagnostic criteria
Stauffer ’s syndrome corresponds to a set of clinical and analytical changes of paraneoplastic nature firstly recognized more than 50 years ago, in association to renal cell carcinoma. A definitive review including universal diagnostic criteria and updated knowledge since the original description is lackin g. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - April 12, 2018 Category: Urology & Nephrology Authors: M ário Fontes-Sousa, Helena Magalhães, Fernando Calais da Silva, Maria Joaquina Maurício Tags: Review article Source Type: research

Identification of men with low-risk biopsy-confirmed prostate cancer as candidates for active surveillance
A combined clinical cell-cycle risk (CCR) score that incorporates prognostic molecular and clinical information has been recently developed and validated to improve prostate cancer mortality (PCM) risk stratification over clinical features alone. As clinical features are currently used to select men for active surveillance (AS), we developed and validated a CCR score threshold to improve the identification of men with low-risk disease who are appropriate for AS. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - April 11, 2018 Category: Urology & Nephrology Authors: Daniel W. Lin, E. David Crawford, Thomas Keane, Brent Evans, Julia Reid, Saradha Rajamani, Krystal Brown, Alexander Gutin, Jonathan Tward, Peter Scardino, Michael Brawer, Steven Stone, Jack Cuzick Tags: Original article Source Type: research

Molecular basis of the effect of MMP-9 on the prostate bone metastasis: A review
Prostate cancer (PCa) is the second most common cancer in men especially after 50 years old. The metastasis of said cancer involves a rise for morbidity, metastasizing 90% of the occasions on bone. Metalloproteinases (MMPs) are involved in the process of bone formation and they are postulated to be involved in the process of metastasizing, in particular MMP-9. This work is justified taking into account the scientific interest of the subject and the quality of the literature sources used. PCa generates a high morbidity and mortality in men, especially due to the process of metastasis, resulting in effects to health and soci...
Source: Urologic Oncology: Seminars and Original Investigations - April 9, 2018 Category: Urology & Nephrology Authors: Emilio Rub én Pego, Isaac Fernández, María Jesús Núñez Tags: Review article Source Type: research