Identification of men with low-risk biopsy-confirmed prostate cancer as candidates for active surveillance

A combined clinical cell-cycle risk (CCR) score that incorporates prognostic molecular and clinical information has been recently developed and validated to improve prostate cancer mortality (PCM) risk stratification over clinical features alone. As clinical features are currently used to select men for active surveillance (AS), we developed and validated a CCR score threshold to improve the identification of men with low-risk disease who are appropriate for AS.

Source: Urologic Oncology: Seminars and Original Investigations - April 11, 2018 Category: Urology & Nephrology Authors: Daniel W. Lin, E. David Crawford, Thomas Keane, Brent Evans, Julia Reid, Saradha Rajamani, Krystal Brown, Alexander Gutin, Jonathan Tward, Peter Scardino, Michael Brawer, Steven Stone, Jack Cuzick Tags: Original article Source Type: research