Postoperative D-dimer predicts venous thromboembolism in patients undergoing urologic tumor surgery
We examined the incidence of pulmonary thromboembolism (PE) and deep venous thromboembolism (DVT) in patients who underwent urologic tumor surgery. The aim of this study was to investigate the postoperative D-dimer for prediction of venous thromboembolism events (VTE), as well as to identify other risk factors associated with the occurrence of thromboembolisms. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - March 26, 2018 Category: Urology & Nephrology Authors: An Shi, Jiwei Huang, Xun Wang, Mingyang Li, Jin Zhang, Yonghui Chen, Yiran Huang Tags: Original article Source Type: research

Intravesical recurrence after bladder sparing treatment of small cell carcinoma of the bladder: Characteristics, treatment, and outcome
The objective of this study is to describe the incidence of intravesical recurrences and their management. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - March 24, 2018 Category: Urology & Nephrology Authors: Maaike van de Kamp, Richard Meijer, Floris Pos, Martijn Kerst, Eric van Werkhoven, Bas van Rhijn, Simon Horenblas, Axel Bex Tags: Original article Source Type: research

The risk of prostate cancer mortality and cardiovascular mortality of nonmetastatic prostate cancer patients: A population-based retrospective cohort study
To assess the risk of prostate cancer (PCa) specific mortality (PCSM) compared to cardiovascular disease mortality (CVDM), or other-cause mortality (OCM) of men with nonmetastatic PCa according to PCa risk groups, primary treatment, and age. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - March 22, 2018 Category: Urology & Nephrology Authors: Katarina L. Matthes, Giulia Pestoni, Dimitri Korol, Mieke Van Hemelrijck, Sabine Rohrmann Tags: Original article Source Type: research

The evolution of bladder cancer genomics: What have we learned and how can we use it?
With advancements in molecular biology techniques, great progress has been made in the understanding of urothelial carcinoma pathogenesis. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - March 22, 2018 Category: Urology & Nephrology Authors: Fran çois Audenet, Kyrollis Attalla, John P. Sfakianos Tags: Review Article Source Type: research

The risk of prostate cancer mortality and cardiovascular mortality of nonmetastatic prostate cancer patients: A population-based retrospective cohort study
To assess the risk of prostate cancer (PCa) specific mortality (PCSM) compared to cardiovascular disease mortality (CVDM), or other-cause mortality (OCM) of men with nonmetastatic PCa according to PCa risk groups, primary treatment, and age. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - March 22, 2018 Category: Urology & Nephrology Authors: Katarina L. Matthes, Giulia Pestoni, Dimitri Korol, Mieke Van Hemelrijck, Sabine Rohrmann Tags: Original article Source Type: research

The evolution of bladder cancer genomics: What have we learned and how can we use it?
With advancements in molecular biology techniques, great progress has been made in the understanding of urothelial carcinoma pathogenesis. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - March 22, 2018 Category: Urology & Nephrology Authors: Fran çois Audenet, Kyrollis Attalla, John P. Sfakianos Tags: Review Article Source Type: research

Key design and analysis principles for quality of life and patient-reported outcomes in clinical trials
We present these principles and argue that adherence to these principles is vital to ensure valid interpretation of clinical trial findings, identify meaningful differences among investigational strategies, and better translate clinical trial results to diverse stakeholders. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - March 20, 2018 Category: Urology & Nephrology Authors: Joseph M. Unger, Riha Vaidya, John L. Gore Tags: Seminars Article Source Type: research

Implementation science theories to inform efforts for de-implementation of urologic oncology care practices resulting in overuse and misuse
The field of implementation science has been conventionally applied in the context of increasing the application of evidence-based practices into clinical care, given evidence of underusage of appropriate interventions in many settings. Increasingly, however, there is recognition of the potential for similar frameworks to inform efforts to reduce the application of ineffective or potentially harmful practices. In this article, we provide some examples of clinical scenarios in which the quality problem may be overuse and misuse, and review relevant theories and frameworks that may inform improvement activities. (Source: Uro...
Source: Urologic Oncology: Seminars and Original Investigations - March 19, 2018 Category: Urology & Nephrology Authors: Matthew E. Nielsen, Sarah A. Birken Tags: Seminars article Source Type: research

CO suppresses prostate cancer cell growth by directly targeting LKB1/AMPK/mTOR pathway in vitro and in vivo
CO is a freely diffusible gas that acts as a physiological mediator of many biological and cellular processes, which has been shown to possess anticancer effect in many kinds of cancers. However, the effect of CO on prostate cancer has not been demonstrated. Therefore, we analyzed the antitumor activities and related mechanisms of CO on prostate cancer in vitro and in vivo. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - March 19, 2018 Category: Urology & Nephrology Authors: Yutao Yan, Caiqi Du, Guohao Li, Lin Chen, Yubo Yan, Gang Chen, Weifeng Hu, Lei Chang Tags: Original article Source Type: research

The relationship of travel distance with cystectomy access and outcomes
Regionalization of care and travel distance may result in unintended consequences for complex surgery such as cystectomy. Our objective was to evaluate effect of differential distance on cystectomy receipt among patients with muscle-invasive bladder cancer (MIBC) and investigate the association between travel distance and cystectomy outcomes such as readmission. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - March 19, 2018 Category: Urology & Nephrology Authors: Angela B. Smith, Anne-Marie Meyer, Ke Meng, Matthew E. Nielsen, Raj Pruthi, Eric Wallen, Michael Woods, Hung-Jui Tan Tags: Original article Source Type: research

Implementation science theories to inform efforts for de-implementation of urologic oncology care practices resulting in overuse and misuse
The field of implementation science has been conventionally applied in the context of increasing the application of evidence-based practices into clinical care, given evidence of underusage of appropriate interventions in many settings. Increasingly, however, there is recognition of the potential for similar frameworks to inform efforts to reduce the application of ineffective or potentially harmful practices. In this article, we provide some examples of clinical scenarios in which the quality problem may be overuse and misuse, and review relevant theories and frameworks that may inform improvement activities. (Source: Uro...
Source: Urologic Oncology: Seminars and Original Investigations - March 19, 2018 Category: Urology & Nephrology Authors: Matthew E. Nielsen, Sarah A. Birken Tags: Seminars article Source Type: research

CO suppresses prostate cancer cell growth by directly targeting LKB1/AMPK/mTOR pathway in vitro and in vivo
CO is a freely diffusible gas that acts as a physiological mediator of many biological and cellular processes, which has been shown to possess anticancer effect in many kinds of cancers. However, the effect of CO on prostate cancer has not been demonstrated. Therefore, we analyzed the antitumor activities and related mechanisms of CO on prostate cancer in vitro and in vivo. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - March 19, 2018 Category: Urology & Nephrology Authors: Yutao Yan, Caiqi Du, Guohao Li, Lin Chen, Yubo Yan, Gang Chen, Weifeng Hu, Lei Chang Tags: Original article Source Type: research