Sustained FXN expression in dorsal root ganglia from a nonreplicative genomic HSV ‐1 vector
ConclusionsOur results support the feasibility of using this vector for sustained neuronal expression of human frataxin for FA gene therapy. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - August 1, 2017 Category: Genetics & Stem Cells Authors: Maria Ventosa, Zetang Wu, Filip Lim Tags: RESEARCH ARTICLE Source Type: research
Mesenchymal stem cells therapy: a promising cell based therapy for treatment of myocardial infraction
ConclusionsAlthough MSCs therapy has achieved considerable attention and progress, critical challenges to be overcome in order to get most effective successful cell based therapy in MI. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - August 1, 2017 Category: Genetics & Stem Cells Authors: Ayman El Sayed Shafei, Mahmoud Ahmed Ali, Hazem G. Ghanem, Ahmed I. Shehata, Ahmed.A Abdelgawad, Hossam R. Handal, Kareem A. Talaat, Ahmed E. Ashaal, Amal S. El ‐Shal Tags: REVIEW ARTICLE Source Type: research
Non ‐invasive Detection of Bladder Cancer via Expression‐targeted Gene Delivery
ConclusionsThe detection system, having shown tumor specificity, and having been calibrated to circadian expression patterns, shows great promise for future investigation of tumor presence both in the urinary bladder and other models of cancer. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - August 1, 2017 Category: Genetics & Stem Cells Authors: Yunlan Fang, B. Wolfson, W.T. Godbey Tags: RESEARCH ARTICLE Source Type: research
Association of DNMT3b gene variants with sporadic Parkinson's disease in a Chinese Han population
ConclusionsOur study strongly suggested that DNMT3b variants are associated with PD in the Chinese Han people, especially females. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - August 1, 2017 Category: Genetics & Stem Cells Authors: Xiang Chen, Yousheng Xiao, Lei Wei, Yijuan Wu, Jianjun Lu, Wenyuan Guo, Shuxuan Huang, Miaomiao Zhou, Mingshu Mo, Zhe Li, Luan Cen, Shaomin Li, ChaohaoYang, Zhuohua Wu, Sophie Hu, Zhong Pei, XinLing Yang, Shaogang Qu, Pingyi Xu Tags: RESEARCH ARTICLE Source Type: research
The effects of gene polymorphisms on glioma prognosis
ConclusionsAge, surgical resection, and chemotherapy influenced the survival rates of glioma patients. TERT, MPHOSPH6, ACYP2, and ZNF208 genes were found to affect glioma prognosis. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - August 1, 2017 Category: Genetics & Stem Cells Authors: Ying Cui, Guolin Li, Mengdan Yan, Jing Li, Tianbo Jin, Shanqu Li, Shijie Mu Tags: RESEARCH ARTICLE Source Type: research
Polymorphisms in homologous recombination repair genes and the risk and survival of breast cancer
ConclusionsThe findings suggested that the polymorphisms in HRR genes were associated with breast cancer risk (RFC1 rs6829064) and prognosis (NRM rs1075496 and LIG3 rs1052536), while RAD54L rs1710286 and RPA1 rs11078676 had null associations with breast cancer. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - August 1, 2017 Category: Genetics & Stem Cells Authors: Yu ‐Huang Liao, Jun‐Ting Ren, Wei Zhang, Zheng‐Zheng Zhang, Ying Lin, Feng‐Xi Su, Wei‐Hua Jia, Lu‐Ying Tang, Ze‐Fang Ren Tags: RESEARCH ARTICLE Source Type: research
Association of HLA Polymorphisms with Occult Hepatitis B Virus Infection in Shaanxi Han Population
ConclusionsOur present results suggest that host HLA gene is an important influencing factor for OBI pathogenesis. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - August 1, 2017 Category: Genetics & Stem Cells Authors: Tianju Wang, Chunmei Shen, Liping Chen, Sheng Liu, Yanhong Ji Tags: RESEARCH ARTICLE Source Type: research
Retraction: ‘MicroRNA‐4656 is a prognostic factor and tumor suppressor in human pancreatic cancer through a downstream target of TrkA’ by Xianglong Tan, Jinyong Lv, Guodong Zhao, Zhiming Zhao, Chenggang Li, Yong Xu and Minggen Hu
(Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - July 27, 2017 Category: Genetics & Stem Cells Tags: RETRACTION Source Type: research
Association of TNFSF13 polymorphisms with IgA nephropathy in a Chinese Han population
ConclusionsThe results of the present study indicate that the genetic variations and gene expression level of TNFSF13 are associated with the susceptibility and severity of IgAN in a Han Chinese population. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - July 27, 2017 Category: Genetics & Stem Cells Authors: Zhong Zhong, Shao ‐Zhen Feng, Ri‐Cong Xu, Zhi‐Jian Li, Feng‐Xian Huang, Pei‐Ran Yin, Wen‐Ting Liu, Meng Wang, Dian‐Chun Shi, Qian Zhou, Xue‐Qing Yu, Ming Li Tags: RESEARCH ARTICLE Source Type: research
Polymer functionalized gold nanoparticles as nonviral gene delivery reagents
ConclusionsNonviral vectors based on gold nanoparticles covalently coupled with PEG and PEI can be used as efficient transfection reagents showing expression levels that are the same or greater than those obtained with commercially available lipoplexes. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - July 27, 2017 Category: Genetics & Stem Cells Authors: M. Mar Encabo ‐Berzosa, Maria Sancho‐Albero, Victor Sebastian, Silvia Irusta, Manuel Arruebo, Jesus Santamaria, Pilar Martín Duque Tags: RESEARCH ARTICLE Source Type: research
Issue Information
No abstract is available for this article. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - July 27, 2017 Category: Genetics & Stem Cells Tags: ISSUE INFORMATION Source Type: research
BMP ‐2 gene activated muscle tissue fragments for osteochondral defect regeneration in the rabbit knee
ConclusionsGene activated muscle tissue grafts showed potential for osteochondral defect repair. There is room for improval through the use of appropriate growth factor combinations. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - July 25, 2017 Category: Genetics & Stem Cells Authors: Volker M. Betz, Alexander Keller, Peter Foehr, Christian Thirion, Michael Salomon, Stefan Rammelt, Hans Zwipp, Rainer Burgkart, Volkmar Jansson, Peter E. M üller, Oliver B. Betz Tags: RESEARCH ARTICLE Source Type: research
Risk of high altitude pulmonary edema and telomere length
(Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - May 23, 2017 Category: Genetics & Stem Cells Authors: Gaurav Sikri, Srinivasa Bhattachar Tags: LETTER TO THE EDITOR Source Type: research
Polymorphisms in the SNRPN gene are associated with obesity susceptibility in a Spanish population
ConclusionsTo our knowledge, this is the first study reporting an association between variability in the SNRPN gene and the risk of being obese. Interestingly, it was the major allele of each SNP that was found to be associated with the risk of weight gain. Further studies analyzing this locus and the possible additive deleterious capability of SNP combinations could be useful for demonstrating the development of obesity. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - May 23, 2017 Category: Genetics & Stem Cells Authors: David Albuquerque, Lic ínio Manco, Luz M. González, Guillermo Gervasini, Goitzane Marcaida Benito, Juan R. González, Raquel Rodríguez‐López Tags: RESEARCH ARTICLE Source Type: research
Stent ‐mediated gene and drug delivery for cardiovascular disease and cancer: A brief insight
Abstract
This review concisely recapitulates the different existing modes of stent‐mediated gene/drug delivery, their considerable advancement in clinical trials and a rationale for other merging new technologies such as nanotechnology and microRNA‐based therapeutics, in addition to addressing the limitations in each of these perpetual stent platforms. Over the past decade, stent‐mediated gene/drug delivery has materialized as a hopeful alternative for cardiovascular disease and cancer in contrast to routine conventional treatment modalities. Regardless of the phenomenal recent developments achieved by coronary inter...
Source: The Journal of Gene Medicine - May 23, 2017 Category: Genetics & Stem Cells Authors: Akshaya Krishnagopal, Aakash Reddy, Dwaipayan Sen Tags: REVIEW ARTICLE Source Type: research
