HPV and non-HPV related subtypes of penile squamous cell carcinoma (SCC): Morphological features and differential diagnosis according to the new WHO classification (2015).
The majority of penile carcinomas are squamous cell carcinomas originating in the squamous mucosa covering glans, coronal sulcus or inner surface of the foreskin, the 3 latter sites comprising the penile anatomical compartments. There is a variegated spectrum of subtypes of penile squamous cell carcinomas, according to recent classification schemes. Currently, because of etiological and prognostic considerations, 2 morphologically and molecularly distinctive groups of subtypes of penile SCCs based on the presence of HPV were delineated. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - December 29, 2014 Category: Pathology Authors: Diego F. Sanchez, Sofía Cañete, María José Fernández-Nestosa, Cecilia Lezcano, Ingrid Rodríguez, José Barreto, Isabel Alvarado-Cabrero, Antonio L. Cubilla Source Type: research
Pathological factors, behavior, and histological prognostic risk groups in subtypes of penile squamous cell carcinomas (SCC)
Pathologists’ contribution in the determination of prognosis in invasive penile squamous cell carcinoma is crucial. The TNM staging system is based on the identification of pathological data. There are multiple pathologically based factors believed to be important in relation to the rates of regional inguinal lymph node and specific cancer death. Among them are tumor site, size, histological subtypes, thickness or anatomical level of invasion, tumor front, and vascular or perineural invasion. The identification of these factors determines the prognostic profile of patients with penile cancer. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - December 26, 2014 Category: Pathology Authors: Diego F. Sanchez, Fernando Soares, Isabel Alvarado-Cabrero, Sofía Cañete, María José Fernández-Nestosa, Ingrid M Rodríguez, José Barreto, Antonio L. Cubilla Source Type: research
Glans resurfacing for precancerous and superficially invasive carcinomas of the glans penis: Pathological specimen handling and reporting
Glans resurfacing is a recently described technique in the management of precancerous lesions and superficial invasive tumours of the glans penis as well as cases of indolent persistent lichen sclerosus. The technique is complex and is usually only practiced in specialist centres with combined urological and plastic surgical expertise. Cosmetic and functional results are better than in more extensive penile surgery, such as glansectomy, for such cases, cancer cure and control is comparable. Knowledge of the technique used and the spectrum of disease are vital for appropriate specimen handling and pathological reporting of ...
Source: Seminars in Diagnostic Pathology - December 26, 2014 Category: Pathology Authors: Catherine M. Corbishley, Brendan Tinwell, Asheesh Kaul, Benjamin Ayres, Nicholas A. Watkin Source Type: research
Clinicopathological features and histogenesis of penile cysts
Cysts arising in the penis are uncommon and can be found anywhere from the urethral meatus to the root of the penis involving glans, foreskin or shaft. Median raphe cysts account for the majority of penile cystic lesions reported in the literature. As their name suggests, they arise on the ventral midline of the penis that extends from the urethral meatus to the scrotum and perineum. Proposed hypotheses for their origin as well as their diverse morphology are discussed. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - December 26, 2014 Category: Pathology Authors: Cecilia Lezcano, Alcides Chaux, Elsa F. Velazquez, Antonio L. Cubilla Source Type: research
Glans resurfacing for precancerous and superficially invasive carcinomas of the glans penis. pathological specimen handling and reporting
Glans resurfacing is a recently described technique in the management of precancerous lesions and superficial invasive tumours of the glans penis as well as cases of indolent persistent lichen sclerosus. The technique is complex and usually only practiced in specialist centres with combined urological and plastic surgical expertise.Cosmetic and functional results are better than in more extensive penile surgery, such as glansectomy, for such cases cancer cure and control is comparable.Knowledge of the technique used and the spectrum of disease are vital for appropriate specimen handling and pathological reporting of these ...
Source: Seminars in Diagnostic Pathology - December 26, 2014 Category: Pathology Authors: Catherine M. Corbishley, Brendan Tinwell, Asheesh Kaul, Benjamin Ayres, Nicholas A. Watkin Source Type: research
