Cytological diagnosis of metastatic malignant melanoma by fine-needle aspiration biopsy
We present selected examples of our experiences and a brief review of the literature to provide cytodiagnostic clues for this malignancy. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - April 14, 2016 Category: Pathology Authors: Kathryn G. Lindsey, Courtney Ingram, Joseph Bergeron, Jack Yang Source Type: research
Metastatic melanoma: Pathologic characterization, current treatment, and complications of therapy
Metastatic melanoma (MM) has the potential to involve virtually any anatomical site, and it also has a wide spectrum of histological appearances. General clinicopathologic data pertaining to MM are presented in this review, together with a discussion of its differential diagnosis and therapy. “Biological” agents used in the treatment of melanoma are considered, along with the pathological features of the complications that they may cause. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - April 14, 2016 Category: Pathology Authors: Mark R. Wick, Alejandro A. Gru Source Type: research
Cutaneous melanoma: A current overview
Cutaneous melanoma continues to increase in frequency, for unknown reasons, and it can pose considerable diagnostic challenges to clinician and pathologists alike. This review considers current concepts pertaining to that tumor, including those concerning epidemiology, clinical diagnosis, histologic findings, adjunctive diagnostic studies, and prognosis. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - April 14, 2016 Category: Pathology Authors: Mark R. Wick Source Type: research
Mucosal melanomas: Site-specific information, comparisons with cutaneous tumors, and differential diagnosis
Melanoma of the skin is the fifth leading new cancer diagnosis, having accounted for almost 77,000 cases and more than 9000 deaths in the United States in 2013. Although cutaneous neoplasms of this type are relatively common, their mucosal counterparts are not. Mucosal melanomas comprise approximately 1.3% of all melanocytic malignancies. Although they are rare, these lesions present at an advanced stage with more adverse prognoses. In addition, at a molecular level, they have proven to be distinct entities because they possess genetic mutations not usually seen in their cutaneous counterparts. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - April 14, 2016 Category: Pathology Authors: Nicole R. Dominiak, Mark R. Wick, M. Timothy Smith Source Type: research
Metastatic melanoma: Pathologic characterization, current treatment, and complications of therapy
Metastatic melanoma (MM) has the potential to involve virtually any anatomical site, and it also has a wide spectrum of histological appearances. General clinicopathologic data pertaining to MM are presented in this review, together with a discussion of its differential diagnosis and therapy. “Biological” agents used in the treatment of melanoma are considered, along with the pathological features of the complications that they may cause. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - April 14, 2016 Category: Pathology Authors: Mark R. Wick, Alejandro A. Gru Source Type: research
Introduction
According to the website of the American Cancer Society, an estimated 76,100 new cases of cutaneous melanoma will be recognized in 2014, and about 9700 annual deaths are expected from that tumor type. Yearly incidence rates for melanoma have risen steadily over the past 30 years, but the reasons for that observation are not fully understood. Malignant melanoma and histologically similar pigmented skin lesions are common diagnostic challenges, and pathologic interpretations thereof are often disputed among experts. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - April 14, 2016 Category: Pathology Authors: Michael Timothy Smith, Mark R. Wick Source Type: research
Cytological diagnosis of metastatic malignant melanoma by fine-needle aspiration biopsy
We present selected examples of our experiences and a brief review of the literature to provide cytodiagnostic clues for this malignancy. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - April 14, 2016 Category: Pathology Authors: Kathryn G. Lindsey, Courtney Ingram, Joseph Bergeron, Jack Yang Source Type: research
Introduction—Pathobiological Features of melanocytic Lesions: Selected Topics
According to the Web site of the American Cancer Society, an estimated 76,100 new cases of cutaneous melanoma will be recognized in 2014, and about 9700 annual deaths are expected from that tumor type. Yearly incidence rates for melanoma have risen steadily over the past 30 years, but the reasons for that observation are not fully understood. Malignant melanoma and histologically similar pigmented skin lesions are common diagnostic challenges, and pathologic interpretations thereof are often disputed among experts. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - April 14, 2016 Category: Pathology Authors: M. Timothy Smith, Mark R. Wick Source Type: research
Selected benign cutaneous lesions that may simulate melanoma histologically
Because cutaneous melanomas manifest a wide spectrum of clinical and pathologic presentations, several other lesions enter into their differential diagnosis. This review considers those entities, including melanocytic hyperplasia, cellular nodules in congenital nevi, atypical lentiginous melanocytic proliferations, “special site” nevi, epithelioid histiocytoma, neurothekeoma, cellular schwannoma, and proliferating scars. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - April 14, 2016 Category: Pathology Authors: Mark R. Wick Source Type: research
Mucosal Melanomas: Site-Specific Information, Comparisons With Cutaneous Tumors, & Differential Diagnosis
Melanoma of the skin is the fifth leading new cancer diagnosis, having accounted for almost 77,000 cases and more than 9000 deaths in the U.S. in 2013. Although cutaneous neoplasms of this type are relatively common, their mucosal counterparts are not. Mucosal melanomas comprise only approximately 1.3% of all melanocytic malignancies. Although they are rare, these lesions present at an advanced stage with more adverse prognoses. In addition, at a molecular level, they have proven to be distinct entities because they possess genetic mutations not usually seen in their cutaneous counterparts. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - April 14, 2016 Category: Pathology Authors: Nicole R. Dominiak, Mark R. Wick, M. Timothy Smith Source Type: research
Cytological diagnosis of metastatic malignant melanoma by fine needle aspiration biopsy
We present selected examples of our experiences and a brief review of the literature to provide cytodiagnostic clues for this malignancy. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - April 14, 2016 Category: Pathology Authors: Kathryn G. Lindsey, Courtney Ingram, Joseph Bergeron, Jack Yang Source Type: research
Blue Nevus & “Malignant Blue Nevus:” A Concise Review
Blue nevi are a heterogeneous group of lesions that can display a variety of different clinicopathological characteristics. Although attempts are made to classify each lesion into defined subtypes, there can be overlap between the subtypes. The clinical and histolopathologic features of common blue nevi and cellular blue nevi are discussed, as well as blue nevi with atypical features and malignant lesions with features of blue nevi. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - April 14, 2016 Category: Pathology Authors: Jessica Zarah Sugianto, Jonathan Scott Ralston, John S. Metcalf, Courtney L. McFaddin, M. Timothy Smith Source Type: research
Cutaneous melanoma: A current overview
Cutaneous melanoma continues to increase in frequency, for unknown reasons, and it can pose considerable diagnostic challenges to clinician and pathologists alike. This review considers current concepts pertaining to that tumor, including those concerning epidemiology, clinical diagnosis, histologic findings, adjunctive diagnostic studies, and prognosis. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - April 14, 2016 Category: Pathology Authors: Mark R. Wick Source Type: research
Introduction
Considering the growing trend for super-specialization amongst pathologists, few people now encounter ophthalmic specimens in their practices. The management of ocular tumors has progressed from ‘life salvage’ to ‘eye salvage’ or ‘vision salvage, ‘ and histopathology plays an important role in determining therapeutic strategies and treatment protocols. In that context, it is essential that we be aware of the appropriate techniques, diagnostic clues, and recent advances for the t reatment and prognostication of ophthalmic tumors. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - March 21, 2016 Category: Pathology Authors: Kaustubh Mulay Source Type: research
Introduction
Considering the growing trend for super-specialization amongst pathologists, few people now encounter ophthalmic specimens in their practices. The management of ocular tumors has progressed from ‘life salvage’ to ‘eye salvage’ or ‘vision salvage, ‘ and histopathology plays an important role in determining therapeutic strategies and treatment protocols. In that context, it is essential that we be aware of the appropriate techniques, diagnostic clues, and recent advances for the treatment and prognostication of ophthalmic tumors. (Source: Seminars in Diagnostic Pathology)
Source: Seminars in Diagnostic Pathology - March 21, 2016 Category: Pathology Authors: Kaustubh Mulay Source Type: research
