Treatment of latent tuberculosis in patients with juvenile rheumatic diseases: a systematic review
Conclusions: Only one case of LTBI activation was observed; there was good treatment adherence and absence of complications during follow-up. More studies are necessary to evaluate the response to the other available therapeutic regimens, with better tolerability assessment and a larger sample. However, the results showed that INH therapy for 9 months and INH therapy plus rifampicin for 3 months had a low rate of LTBI activation and complications.RESUMO Introdu ção: Crianças e adolescentes com doenças reumáticas em terapia anti-TNF- α s ão grupo de risco para ativação da infecção latente por Mycobacterium tube...
Source: Revista Brasileira de Reumatologia - June 26, 2017 Category: Rheumatology Source Type: research
Influence of periodontal treatment on rheumatoid arthritis: a systematic review and meta-analysis
Conclusions: The reduction of DAS 28 in patients with rheumatoid arthritis after periodontal treatment suggests that the improvement of periodontal condition is beneficial to these patients. Further randomized controlled clinical trials are necessary to confirm this finding.RESUMO Objetivo: Avaliar a influ ência do tratamento periodontal sobre a atividade da doença na artrite reumatoide. Métodos: Pesquisaram-se as bases de dados Medline/PubMed, The Cochrane Library, Clinical Trials, SciELO e Lilacs em busca de estudos publicados até dezembro de 2014. Incluíram-se estudos prospectivos que avaliar am pacientes com mai...
Source: Revista Brasileira de Reumatologia - June 26, 2017 Category: Rheumatology Source Type: research
Inadequate pain relief among patients with primary knee osteoarthritis
Conclusions: Our findings indicate that improvements are needed in the management of pain in knee OA in order to achieve better outcomes in terms of pain relief, function and quality of life.RESUMO Antecedentes: Apesar dos tratamentos muito difundidos para a osteoartrite (OA), dados sobre os padr ões de tratamento, a adequação do alívio da dor e a qualidade de vida são limitados. O estudo multinacional prospectivo Survey of Osteoarthritis Real World Therapies (SORT) foi projetado para investigar esses aspectos. Objetivos: Analisar as características e os desfechos relatados pelo pacie nte do conjunto de dados portu...
Source: Revista Brasileira de Reumatologia - June 26, 2017 Category: Rheumatology Source Type: research
Association between demyelinating disease and autoimmune rheumatic disease in a pediatric population
Conclusion: Among patients with demyelinating diseases diagnosed in childhood included in this study there was a high frequency of antinuclear antibody positivity but a lower association with rheumatologic autoimmune diseases than that observed in studies conducted in adults.RESUMO Introdu ção: Esclerose múltipla (EM) e neuromielite óptica (NMO) são doenças desmielinizantes do sistema nervoso central. A autoimunidade entre pacientes com doenças desmielinizantes e seus parentes tem sido amplamente investigada e discutida. Estudos recentes demonstram maior incidência de doenças reumáticas autoimunes entre pacient...
Source: Revista Brasileira de Reumatologia - June 26, 2017 Category: Rheumatology Source Type: research
Falls and their association with physical tests, functional capacity, clinical and demographic factors in patients with rheumatoid arthritis
Conclusion: It was observed that the occurrence of falls and the fear of falling are quite common in this population. The occurrence of falls in this sample of rheumatoid arthritis patients bears no relation to disease activity, functional capacity, or physical fitness tests.RESUMO Objetivo: Avaliar a ocorr ência de quedas reportadas por pacientes com artrite reumatoide (AR) e sua associação com a atividade da doença, capacidade funcional e aptidão física. Material e métodos: Estudo transversal com uma amostra de 97 pacientes com AR em Marília (SP), entre 2012 e 2013. Foram usados instrumentos validados na popul...
Source: Revista Brasileira de Reumatologia - June 26, 2017 Category: Rheumatology Source Type: research
Are the women with Sjögren's Syndrome satisfied with their sexual activity?
Conclusions: Women with SS experience less satisfaction with sexual activity, which can be affected by age, vaginal dryness, physical pain, and impaired function due to the disease. Therefore, rheumatologists should pay attention to these symptoms and management.RESUMO Objetivo: As mulheres com s índrome de Sjögren (SS) muitas vezes experimentam secura vaginal e dispareunia, juntamente com sintomas glandulares e extraglandulares. Este estudo objetivou avaliar a função sexual e a qualidade de vida de mulheres com SS. Métodos: Estudaram-se 46 mulheres pré-menopáusicas com SS e 47 contr oles pareados por idade. Avali...
Source: Revista Brasileira de Reumatologia - June 26, 2017 Category: Rheumatology Source Type: research
Impact of rheumatoid arthritis in the public health system in Santa Catarina, Brazil: a descriptive and temporal trend analysis from 1996 to 2009
Conclusion: During the observed period, a reduction in the number of hospital admissions for both clinical and orthopedic surgical procedures related to this disease was observed. Nevertheless, there was an increase in the cost of medical admissions.RESUMO Introdu ção: Poucos estudos fizeram uma análise descritiva e de tendência dos dados disponíveis do Sistema Único de Saúde (SUS) entre os períodos pré e pós-dispensação gratuita do tratamento medicamentoso da artrite reumatoide (AR) sob a perspectiva do sistema público de saúde em termos de cus to direto da doença entre adultos e idosos moradores do Estado...
Source: Revista Brasileira de Reumatologia - June 26, 2017 Category: Rheumatology Source Type: research
Impacts of social support on symptoms in Brazilian women with fibromyalgia
ABSTRACT We aimed to assess the impact of social support on symptoms in Brazilian women with FM. An observational, descriptive study enrolling 66 women who met the 1990 American College of Rheumatology (ACR) criteria. Social support was measured by the Social Support Survey (MOS-SSS), functionality was evaluated using the Fibromyalgia Impact Questionnaire (FIQ), depression was assessed using the Beck Depression Inventory (BDI), anxiety was measured using the Hamilton Anxiety Scale (HAS), affectivity was measured by Positive and Negative Affect Schedule (PANAS), and algometry was carried out to record pressure pain threshol...
Source: Revista Brasileira de Reumatologia - June 26, 2017 Category: Rheumatology Source Type: research
Unbalanced expression of aryl hydrocarbon receptor in peripheral blood CCR6+CD4+ and CD4+CD25+T cells of rheumatoid arthritis
Conclusion: AhR may participate in the pathological progress of RA by controlling the differentiation of Th17 and Treg cells in peripheral blood.RESUMO Objetivo: Analisar o papel do receptor de hidrocarboneto ar ílico (AhR) nos linfócitos T CCR6+ CD4+ e CD4+ CD25+ no sangue periférico de pacientes com artrite reumatoide (AR). Métodos: Foi aplicada citometria de fluxo para determinar a proporção de células AhR positivas em linfócitos CCR6+ CD4+ e CD4+ CD25+ do sangue periférico e células mononucle ares periféricas de cada indivíduo. Os níveis de expressão relativa de ácido ribonucleico mensageiro (do inglê...
Source: Revista Brasileira de Reumatologia - June 26, 2017 Category: Rheumatology Source Type: research
Independence of carbohydrate-deficient isoforms of transferrin and cyclic citrullinated peptides in rheumatoid arthritis
Conclusions: These results suggest that the changes in CDT and anti-CCP concentrations are not associated with oneself and indicate on the independence of these posttranslational modifications in rheumatoid arthritis. Only the alterations in transferrin glycosylation reflected the activity of RA.RESUMO Objetivo: Avaliar a rela ção entre os dois tipos de modificações pós-translacionais de proteínas na AR: glicosilação no caso da transferrina deficiente em carboidrato (TDC) e citrulinação por meio dos anticorpos no caso do antipeptídeo citrulinado cíclico (anti-CCP). Métodos: O estudo foi feito em 50 pacientes...
Source: Revista Brasileira de Reumatologia - June 26, 2017 Category: Rheumatology Source Type: research
Interventional rheumatology: the competence of Brazilian rheumatologists
Conclusions Performing more complex invasive procedures and over 6-month training in interventional rheumatology were variables associated with enhanced interventional profile. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - June 20, 2017 Category: Rheumatology Source Type: research
Quality of life and functional capacity of patients with adhesive capsulitis: identifying risk factors associated to better outcomes after treatment with nerve blocking
Conclusions Quality of life and functional capacity of the patients improve at the end of procedure. Older patients and higher education levels are the risk factors most associated to satisfactory quality of life and better functional capacity after treatment with nerve blocking. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - June 13, 2017 Category: Rheumatology Source Type: research
Molecular evidence of Borrelia burgdorferi sensu lato in patients in Brazilian central-western region
This study opens up promising perspectives and reinforces the need for additional studies to determine the epidemiological characteristics of the disease, as well as the impact of the prevalence of Brazilian borreliosis in Mato Grosso do Sul State, Brazil. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - June 3, 2017 Category: Rheumatology Source Type: research
Salivary β2-microglobulin positively correlates with ESSPRI in patients with primary Sjögren's syndrome
This study aims to assess, through a systematic review of the literature according to Prisma (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) quality criteria, the risk of cancer in patients with juvenile rheumatic disease, and its association with biological agents. The criteria described by the Strengthening the Reporting of Observational Studies in Epidemiology initiative were used in order to assess the methodological quality of those individual items selected in this study. We analyzed nine publications, from a total of 251 papers initially selected. There was an increase in cancer risk in the popu...
Source: Revista Brasileira de Reumatologia - May 4, 2017 Category: Rheumatology Source Type: research
Biological therapy and development of neoplastic disease in patients with juvenile rheumatic disease: a systematic review
This study aims to assess, through a systematic review of the literature according to Prisma (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) quality criteria, the risk of cancer in patients with juvenile rheumatic disease, and its association with biological agents. The criteria described by the Strengthening the Reporting of Observational Studies in Epidemiology initiative were used in order to assess the methodological quality of those individual items selected in this study. We analyzed nine publications, from a total of 251 papers initially selected. There was an increase in cancer risk in the popu...
Source: Revista Brasileira de Reumatologia - May 4, 2017 Category: Rheumatology Source Type: research
