Erratum
Conclusion: Leflunomide led to sustained remission in approximately half of patients at a mean time of 12 months and was well tolerated by TA patients.RESUMO Objetivo: Avaliar os dados de seguimento em longo prazo em rela ção à eficácia e toxicidade do tratamento com leflunomida em pacientes com arterite de Takayasu (AT) previamente recrutados no estudo aberto original dos efeitos de curto prazo da leflunomida na AT. Métodos: Fez-se um estudo longitudinal aberto de longo prazo com pacientes que preencheram os c ritérios para AT da American College of Rheumatology de 1990 e que participaram de um estudo anterior que...
Source: Revista Brasileira de Reumatologia - August 22, 2016 Category: Rheumatology Source Type: research
Leflunomide in Takayasu arteritis – A long term observational study
Conclusion: Leflunomide led to sustained remission in approximately half of patients at a mean time of 12 months and was well tolerated by TA patients.RESUMO Objetivo: Avaliar os dados de seguimento em longo prazo em rela ção à eficácia e toxicidade do tratamento com leflunomida em pacientes com arterite de Takayasu (AT) previamente recrutados no estudo aberto original dos efeitos de curto prazo da leflunomida na AT. Métodos: Fez-se um estudo longitudinal aberto de longo prazo com pacientes que preencheram os c ritérios para AT da American College of Rheumatology de 1990 e que participaram de um estudo anterior que...
Source: Revista Brasileira de Reumatologia - August 22, 2016 Category: Rheumatology Source Type: research
Intracerebral hemorrhage with a favorable outcome in a patient with childhood primary angiitis of the central nervous system
We present the case of a boy with cPACNS that previously suffered an ischemic stroke. At the age of 7 years and 10 months, he presented a sudden and severe headache, vomiting and reduction in consciousness level (Glasgow coma scale 7), requiring prompt tracheal intubation. Brain computed tomography demonstrated intraparenchymal hematoma in the right parieto-occipital lobe and a small focus of bleeding in the right frontal lobe, vasogenic edema, herniation of the uncus and a 10 mm deviation to the left from the midline. C-reactive protein (9.2 mg/dL) and von Willebrand factor (vWF) antigen (202%) were elevated. Decompressiv...
Source: Revista Brasileira de Reumatologia - August 22, 2016 Category: Rheumatology Source Type: research
The effects of the Pilates method in the elderly: a systematic review
ABSTRACT Several studies show the benefits of including muscle strength and aerobic physical activity in the routine of elderly people. Among the various possibilities of physical activity, the Pilates method has become a popular modality in recent years, through a system of exercises enabling to work the whole body and that corrects posture and realigns the muscles, developing the body stability needed for a healthier life. The aim of this study was to review the current evidence on the effects of the practice of the Pilates method in the elderly. A systematic literature review was conducted in the following electronic da...
Source: Revista Brasileira de Reumatologia - August 22, 2016 Category: Rheumatology Source Type: research
Swimming and cycling do not cause positive effects on bone mineral density: a systematic review
ABSTRACT Osteoporosis is considered a common metabolic bone disease and its prevalence is increasing worldwide. In this context, physical activity has been used as a non-pharmacological tool for prevention and auxiliary treatment of this disease. The aim of this systematic review was to evaluate the effects of cycling and swimming practice on bone mineral density (BMD). This research was conducted in accordance with the recommendations outlined by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The studies were consulted in the period from 2004 to 2014, through major electronic databases: PubMed ®,...
Source: Revista Brasileira de Reumatologia - August 22, 2016 Category: Rheumatology Source Type: research
Low vitamin D serum levels in diffuse systemic sclerosis: a correlation with worst quality of life and severe capillaroscopic findings
Conclusion: The present study provides novel evidence demonstrating that low levels of 25OHD have a negative impact in diffuse SSc QoL and further studies are needed to define whether vitamin D supplementation can improve health related QoL in these patients. The additional observation of a correlation with severe NC alterations suggests a possible role of 25OHD in the underlying SSc vascular involvement.RESUMO Objetivo: O objetivo deste estudo foi analisar a correla ção entre os níveis de vitamina D e parâmetros clínicos, densidade mineral óssea (DMO), qualidade de vida (QV) e capilaroscopia periungueal (CPU) em pa...
Source: Revista Brasileira de Reumatologia - August 22, 2016 Category: Rheumatology Source Type: research
Prevalence of anxiety, depression and kinesiophobia in patients with low back pain and their association with the symptoms of low back spinal pain
Conclusion: There was no association between the groups and anxiety and depression. However, there was a positive correlation between kinesiophobia and the Organic group. Studies of other patient samples are needed to confirm the reproducibility and validity of these data in other populations.RESUMO Objetivo: Avaliar a preval ência de ansiedade, depressão e cinesiofobia e sua associação com os sintomas da lombalgia. Métodos: Foram divididos 65 pacientes em três grupos: orgânicos, orgânicos amplificados e não orgânicos. Eles responderam ao Inventário de Ansiedade de Beck, Inventário de Depressão de Beck e Es ...
Source: Revista Brasileira de Reumatologia - August 22, 2016 Category: Rheumatology Source Type: research
Substance use and sexual function in juvenile idiopathic arthritis
Conclusion: A high risk for substance abuse/dependence was observed in both JIA and controls. JIA substance users were more likely to have sexual intercourse. Therefore, routine screening is suggested in all visits of JIA adolescents.RESUMO Objetivo: Avaliar o uso de álcool/tabaco/drogas ilícitas e a função sexual em adolescentes com artrite idiopática juvenil (AIJ) e controles saudáveis. Métodos: Selecionaram-se 174 adolescentes com doenças reumatológicas pediátricas. Fez-se um estudo transversal com 54 pacientes com AIJ e 35 controles. Foram feitas avaliações de dados demográficos/antropométricos e marcad...
Source: Revista Brasileira de Reumatologia - August 22, 2016 Category: Rheumatology Source Type: research
Familial autoimmunity and polyautoimmunity in 60 Brazilian Midwest patients with systemic sclerosis
Conclusions: From the high prevalence of coexisting autoimmune diseases found in SSc patients, we stress the importance of the concept of shared autoimmunity, in order to promote a continued vigilance and promptly diagnose other possible autoimmune disease in patients , or in their kin.RESUMO Introdu ção: A esclerose sistêmica (ES) é uma enfermidade do tecido conjuntivo de etiologia desconhecida, caracterizada pela tríade de injúria vascular, autoimunidade e fibrose tecidual. Sabe-se que uma história familiar positiva representa o maior fator de risco já identificado para o desenvolvimen to da ES em um determinado...
Source: Revista Brasileira de Reumatologia - August 22, 2016 Category: Rheumatology Source Type: research
Serum Clara cell 16-kDa protein levels and lung impairment in systemic sclerosis patients
Conclusions: Clara cell 16-kDa protein levels can be considered as a supplemental serum biomarker for systemic sclerosis associated interstitial lung disease.RESUMO Objetivo: Avaliar a utilidade cl ínica das medições séricas da proteína de células de Clara de 16-kDa (CC16) em relação ao sistema de estadiamento para doença pulmonar intersticial associada a esclerose sistêmica (DPI-ES). Materiais e métodos: Foram determinados os níveis séricos de CC16 por ELISA em 28 pacientes com ES e 30 controles saudáveis e correlacionados com o sistema de estadiamento para DPI-ES em pacientes com ES. O envolvimento pulmon...
Source: Revista Brasileira de Reumatologia - August 22, 2016 Category: Rheumatology Source Type: research
18F-Fluorodeoxyglucose positron emission tomography and serum cytokines and matrix metalloproteinases in the assessment of disease activity in Takayasu's arteritis
Conclusions: Higher serum IL-6 and TNF α levels as well as higher 18F-FDG uptake in arterial wall are associated with active TA.RESUMO Objetivo: Avaliar a capta ção de 18F-fluordesoxiglicose (FDG) na tomografia por emissão de pósitrons – tomografia computadorizada (PET-CT) – e os n íveis séricos de diferentes citocinas e da metaloproteinases da matriz (MMP) em pacientes com arterite de Takayasu (AT) e associações com a atividade da doença. Métodos: Foram mensurados os níveis séricos do fator de necrose tumoral- α (TNF- α ), interleucina (IL)-2, IL-6, IL-8, IL-12, IL-18, MMP-3 e MMP-9 em 36 paciente...
Source: Revista Brasileira de Reumatologia - August 22, 2016 Category: Rheumatology Source Type: research
Overlap between systemic sclerosis and rheumatoid arthritis: a distinct clinical entity?
Conclusions: While the frequency of clinical arthritis observed in patients with systemic sclerosis was 32.8%, the true overlap between of SSc and RA was 6.6% in this study. We also observed the frequency of positive anti-CCP in 20% of patients with arthritis versus no patients with SSc without arthritis.RESUMO Introdu ção: A esclerose sistêmica (ES) é uma enfermidade do tecido conjuntivo de caráter autoimune caracterizada pela tríade de injúria vascular, autoimunidade (celular e humoral) e fibrose tecidual. Estima-se que a dor musculoesquelética seja uma queixa frequente dos pacientes com ES, que oscila e ntre 40...
Source: Revista Brasileira de Reumatologia - August 22, 2016 Category: Rheumatology Source Type: research
The search for new biomarkers in systemic sclerosis
(Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - August 22, 2016 Category: Rheumatology Source Type: research
Rheumatoid arthritis and sleep quality
Conclusions Most of RA patients do not have a good sleep quality. Depression and risk of sleep apnea are independently associated with sleep impairment. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - August 12, 2016 Category: Rheumatology Source Type: research
Impacts of social support on symptoms in Brazilian women with fibromyalgia
Publication date: Available online 9 August 2016 Source:Revista Brasileira de Reumatologia (English Edition) Author(s): Rodrigo Pegado de Abreu Freitas, Sandra Cristina de Andrade, Maria Helena Constantino Spyrides, Maria Thereza Albuquerque Barbosa Cabral Micussi, Maria Bernardete Cordeiro de Sousa We aimed to assess the impact of social support on symptoms in Brazilian women with FM. An observational, descriptive study enrolling 66 women who met the 1990 American College of Rheumatology (ACR) criteria. Social support was measured by the Social Support Survey (MOS-SSS), functionality was evaluated using the Fibromy...
Source: Revista Brasileira de Reumatologia - August 9, 2016 Category: Rheumatology Source Type: research
