Brazilian Journal of Rheumatology at 60 years
(Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - October 9, 2017 Category: Rheumatology Source Type: research
Determinants of quality of life in Paget's disease of bone
Conclusion The main disease-related factor associated with SF-36 results in Paget's disease of bone patients was bone pain, while bone pain and deformities were associated with WHOQOL-bref. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - September 28, 2017 Category: Rheumatology Source Type: research
Achilles tendon xanthoma
ABSTRACT Rheumatic fever is still currently a prevalent disease, especially in developing countries. Triggered by a Group A β -hemolytic Streptococcus infection, the disease may affect genetically predisposed patients. Rheumatic carditis is the most important of its clinical manifestations, which can generate incapacitating sequelae of great impact for the individual and for society. Currently, its diagnosis is made based on the Jones criteria, established in 1992 by the American Heart Association. In 2015, the AHA carried out a significant review of these criteria, with new diagnostic parameters and recommendations. In t...
Source: Revista Brasileira de Reumatologia - August 28, 2017 Category: Rheumatology Source Type: research
Rheumatic fever: update on the Jones criteria according to the American Heart Association review - 2015
ABSTRACT Rheumatic fever is still currently a prevalent disease, especially in developing countries. Triggered by a Group A β -hemolytic Streptococcus infection, the disease may affect genetically predisposed patients. Rheumatic carditis is the most important of its clinical manifestations, which can generate incapacitating sequelae of great impact for the individual and for society. Currently, its diagnosis is made based on the Jones criteria, established in 1992 by the American Heart Association. In 2015, the AHA carried out a significant review of these criteria, with new diagnostic parameters and recommendations. In t...
Source: Revista Brasileira de Reumatologia - August 28, 2017 Category: Rheumatology Source Type: research
Prevalence of fibromyalgia: literature review update
ABSTRACT The present study aimed to update the literature review on the prevalence of fibromyalgia published in 2006. A bibliographical survey was carried out from 2005 to 2014 in the MEDLINE, Web of Science, Embase, LILACS and SciELO databases and 3274 records were identified. Five researchers selected the studies, following the inclusion criteria: studies that obtained the prevalence of fibromyalgia. Fibromyalgia studies in associated diseases were excluded. When screening by title and abstract, 2073 irrelevant articles were excluded. The full texts of 210 articles were evaluated for eligibility and this review included ...
Source: Revista Brasileira de Reumatologia - August 28, 2017 Category: Rheumatology Source Type: research
Critical revision of the medical treatment of gout in Brazil
ABSTRACT Gout is considered the most common form of inflammatory arthritis in men over 40 years. The authors present a brief review of the current treatment of gout and discuss the existing pharmacological limitations in Brazil for the treatment of this disease. Although allopurinol is still the main drug administered for decreasing serum levels of uric acid in gout patients in this country, the authors also present data that show a great opportunity for the Brazilian drug market for the treatment of hyperuricemia and gout and especially for patients using private and public (SUS) health care systems.RESUMO A gota é consi...
Source: Revista Brasileira de Reumatologia - August 28, 2017 Category: Rheumatology Source Type: research
Relapsing polychondritis: prevalence of cardiovascular diseases and its risk factors, and general disease features according to gender
ABSTRACT The comorbidities in relapsing polychondritis have been scarcely described in the literature. Moreover, apart from a few relapsing polychondritis epidemiological studies, no studies specifically addressing relapsing polychondritis distribution according to gender are available. Therefore, the objectives of the present study were: (a) to analyze the prevalence of cardiovascular diseases and its risk factors in a series of patients with relapsing polychondritis; (b) to determine the influence of gender on relapsing polychondritis. A cross-sectional tertiary single center study evaluating 30 relapsing polychondritis ...
Source: Revista Brasileira de Reumatologia - August 28, 2017 Category: Rheumatology Source Type: research
Signs and symptoms of rheumatic diseases as first manifestation of pediatric cancer: diagnosis and prognosis implications
Conclusion: The constitutional and mus culoskeletal symptoms common to rheumatic and neoplastic diseases can delay the diagnosis and consequently worsen the prognosis of neoplasms. Initial blood count and bone marrow smear may be normal in the initial framework of neoplasms. Thus, the clinical follow-up of these cases becomes imperative and the treatment, mainly with corticosteroids, should be delayed until diagnostic definition.RESUMO Objetivo: Avaliar a preval ência e descrever as principais manifestações clínicas, os exames complementares, o tratamento e a evolução de crianças com doenças neoplásicas atendidas...
Source: Revista Brasileira de Reumatologia - August 28, 2017 Category: Rheumatology Source Type: research
Obesity is the main determinant of insulin resistance more than the circulating pro-inflammatory cytokines levels in rheumatoid arthritis patients
Conclusions: Obesity appears to be a dominant condition above inflammation to produce IR in RA patients. The dissociation of the inflammation and obesity components to produce IR suggests the need of an independent therapeutic strategy in obese patients with RA.RESUMO Introdu ção: O bloqueio sistêmico do Fator de Necrose Tumoral- α (TNF- α ) nos indiv íduos com artrite reumatoide (AR) com resistência à insulina (RI) parece produzir mais melhoria na sensibilidade à insulina em pacientes com AR com peso normal do que em pacientes obesos com AR. Isso sugere que a inflamação sistêmica e a obesidade são fatores d...
Source: Revista Brasileira de Reumatologia - August 28, 2017 Category: Rheumatology Source Type: research
Higher body mass index and anti-drug antibodies predict the discontinuation of anti-TNF agents in Korean patients with axial spondyloarthritis
ABSTRACT Objective: The development of anti-drug antibodies against tumor necrosis factor inhibitors is a likely explanation for the failure of TNF-inhibitors in patients with spondyloarthritis. Our study determined the existence and clinical implications of ADAbs in axial spondyloarthritis patients. Methods: According to the Assessment of SpondyloArthritis International Society classification criteria for axial spondyloarthritis, patients treated with adalimumab or infliximab were recruited consecutively. Serum samples were collected at enrollment to measure anti-drug antibodies and drug levels. Results: Of 100 patient...
Source: Revista Brasileira de Reumatologia - August 28, 2017 Category: Rheumatology Source Type: research
Fear-avoidance beliefs increase perception of pain and disability in Mexicans with chronic low back pain
Conclusion: The present study suggests that there is a strong relationship between pain severity, FABQ scores, and functional disability in Mexicans with chronic LBP.RESUMO Introdu ção: As crenças de medo e evitação estão relacionadas com o prognóstico da cronicidade da lombalgia nas fases subagudas; contudo, na dor crônica, não é clara a influência desses fatores. Sugeriu-se que um estudo populacional pode determinar a magnitude da influência da lombalgia sobre a incapacidade e a dor. Atualmente não há informação a esse respeito na população mexicana. Objetivo: Analisar a relação entre as crenças de...
Source: Revista Brasileira de Reumatologia - August 28, 2017 Category: Rheumatology Source Type: research
Association between body mass index and osteoporosis in women from northwestern Rio Grande do Sul
Conclusion: Obese women had lower prevalence of osteopenia compared with normal weight subjects and also with lower prevalence of osteoporosis as compared to normal- and overweight women.RESUMO Objetivo: Verificar a associa ção entre o índice de massa corporal (IMC) e a densidade mineral óssea (DMO) em mulheres pós-menopáusicas. Métodos: Estudo observacional, com mulheres pós-menopáusicas submetidas à densitometria óssea em Palmeira das Missões (RS). Dados sociodemográficos, de risco para a osteoporose e do consumo alimentar foram avaliados por meio de formulário específico. O IMC foi calculado de acordo c...
Source: Revista Brasileira de Reumatologia - August 28, 2017 Category: Rheumatology Source Type: research
Rheumatoid arthritis and sleep quality
Conclusions: Most of RA patients do not have a good sleep quality. Depression and risk of sleep apnea are independently associated with sleep impairment.RESUMO Antecedentes: Os dist úrbios do sono são comuns em pacientes com artrite reumatoide (AR) e contribuem para a perda da qualidade de vida. Objetivo: Estudar as associações entre a qualidade do sono e a dor, depressão e atividade da doença na AR. Métodos: Estudo observacional transversal com 112 pacientes com AR su bmetidos à avaliação do DAS-28, escala de Epworth para sonolência diurna, qualidade do sono pelo índice de Pittsburg, risco de apneia do sono...
Source: Revista Brasileira de Reumatologia - August 28, 2017 Category: Rheumatology Source Type: research
Analysis of four serum biomarkers in rheumatoid arthritis: association with extra articular manifestations in patients and arthralgia in relatives
Conclusions: A higher number of biomarkers was present in RA patients with EAMs. Positivity of biomarkers was related to arthralgia in relatives. These findings reinforce the link between distinct biomarkers and the pathophysiologic mechanisms of AR.RESUMO Objetivos: Avaliar a frequ ência de quatro marcadores sorológicos em pacientes com AR e seus familiares e identificar possíveis associações com achados clínicos da doença. Métodos: Estudo analítico transversal. Determinaram-se os níveis de anticorpos antipeptídeo citrulinado cíclico (anti-CCP), anticorpos antivim entina citrulinada-mutada (anti-MCV) e fator...
Source: Revista Brasileira de Reumatologia - August 28, 2017 Category: Rheumatology Source Type: research
Which is the best cutoff of body mass index to identify obesity in female patients with rheumatoid arthritis? A study using dual energy X-ray absorptiometry body composition
Conclusion: A large percentage of patients were obese. The traditional cutoff points used for obesity were not suitable for our sample. For this female population with established RA, BMI cutoff point of 25 kg/m2 and WC cutoff point of 86 cm were the most appropriate to detect obesity.RESUMO Introdu ção: Medidas antropométricas universalmente usadas para diagnosticar obesidade na população geral podem não apresentar a mesma performance em pacientes com artrite reumatoide. Objetivos: Determinar pontos de corte do índice de massa corporal (IMC) e da circunferência de cintura (CC) para de tecção de obesidade em mu...
Source: Revista Brasileira de Reumatologia - August 28, 2017 Category: Rheumatology Source Type: research
