Poor muscle strength and function in physically inactive childhood-onset systemic lupus erythematosus despite very mild disease
Conclusion Physically inactive C-SLE patients with very mild disease showed reduced muscle strength and functionality when compared with healthy controls matched by physical activity levels. These findings suggest C-SLE patients may greatly suffer from a physically inactive lifestyle than healthy controls do. Moreover, some sub-clinical “residual” effect of the disease or its pharmacological treatment seems to affect C-SLE patients even with a well-controlled disease. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - August 8, 2016 Category: Rheumatology Source Type: research
Contraception for adolescents with chronic rheumatic diseases
Publication date: Available online 6 August 2016 Source:Revista Brasileira de Reumatologia (English Edition) Author(s): Benito Lourenço, Katia T. Kozu, Gabriela N. Leal, Marco F. Silva, Elisabeth G.C. Fernandes, Camila M.P. França, Fernando H.C. Souza, Clovis A. Silva Contraception is an important issue and should be a matter of concern in every medical visit of adolescent and young patients with chronic rheumatic diseases. This narrative review discusses contraception methods in adolescents with juvenile systemic lupus erythematosus (JSLE), antiphospholipid syndrome (APS), juvenile idiopathic arthritis (JIA) a...
Source: Revista Brasileira de Reumatologia - August 7, 2016 Category: Rheumatology Source Type: research
A new musculoskeletal ultrasound scoring system (US10) of the hands and wrist joints for evaluation of early rheumatoid arthritis patients
Conclusion The proposed US10 scoring system proved to be a useful tool for monitoring inflammation and joint damage in early RA patients, demonstrating significant correlations with longitudinal changes in disease activity and functional status. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - August 6, 2016 Category: Rheumatology Source Type: research
Role of Hypoxia Inducible Factor-1 α signaling pathway in osteoarthritis: a systematic review
Publication date: Available online 5 August 2016 Source:Revista Brasileira de Reumatologia (English Edition) Author(s): Javier Fernández-Torres, Gabriela Angélica Martínez-Nava, María Concepción Gutiérrez-Ruíz, Luis Enrique Gómez-Quiroz, Marwin Gutiérrez Osteoarthritis is the most common form of arthritis and is frequently diagnosed and managed in primary care; it is characterized by loss of articular hyaline cartilage, which is a unique connective tissue that physiologically lacks blood vessels. Articular cartilage survives in a microenvironment devoid of oxygen, which is regulated by hypoxia inducible fac...
Source: Revista Brasileira de Reumatologia - August 5, 2016 Category: Rheumatology Source Type: research
Clinical characteristics and frequency of TLR4 polymorphisms in Brazilian patients with ankylosing spondylitis
Conclusions TLR4 polymorphisms 399 and 299 were not more frequent in patients with AS in comparison to the health controls and none of the clinical variables were associated with these polymorphisms. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - August 5, 2016 Category: Rheumatology Source Type: research
Use of the Lower Extremity Functional Scale (LEFS-Brazil) questionnaire compared to Lequesne Algofunctional Index for definition of knee and hip osteoarthritis severity
Conclusion It is possible to identify severe functional impairment for knee or hip OA considering scores lower than 48 points according to LEFS-Brazil. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - August 3, 2016 Category: Rheumatology Source Type: research
Locomotive syndrome in the elderly: translation, cultural adaptation, and Brazilian validation of the tool 25-question Geriatric Locomotive Function Scale
Conclusion GLFS 25-P proved to be a reliable and valid tool in Locomotive Syndrome screening for the elderly population. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - August 2, 2016 Category: Rheumatology Source Type: research
Back pain and behavioral habits of high school students: a comparative study of two Brazil's regions
Conclusion We showed differences between cities and this type of information can support the preparation of specific prevention programs in the school for each situation and city. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - July 30, 2016 Category: Rheumatology Source Type: research
Use of pamidronate for osteoporosis treatment in public health care in Brazil
Conclusion The intravenous pamidronate in a group of postmenopausal women with predominant high risk of fracture promoted an isolated gain in the spine BMD, even though, clinical randomized trials are needed to confirm its anti-fracture efficacy. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - July 29, 2016 Category: Rheumatology Source Type: research
Erratum to “Recommendations from the Brazilian Society of Rheumatology on the diagnosis and treatment of intestinal parasitic infections in patients with autoimmune rheumatic disorders” [Rev Bras Reumatol. 2015;55(4):368–380]
Publication date: July–August 2016 Source:Revista Brasileira de Reumatologia (English Edition), Volume 56, Issue 4 Author(s): Alessandra Sousa Braz, Carlos Augusto Ferreira de Andrade, Licia Maria Henrique da Mota, Caliandra Maria Bezerra Luna Lima (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - July 28, 2016 Category: Rheumatology Source Type: research
Overlap between systemic sclerosis and rheumatoid arthritis: a distinct clinical entity?
Conclusions While the frequency of clinical arthritis observed in patients with systemic sclerosis was 32.8%, the true overlap between of SSc and RA was 6.6% in this study. We also observed the frequency of positive anti-CCP in 20% of patients with arthritis versus no patients with SSc without arthritis. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - July 28, 2016 Category: Rheumatology Source Type: research
Rituximab for the therapy of systemic sclerosis: a series of 10 cases in a single center
This study was conducted with the aim to retrospectively evaluate all patients who used RTX for the treatment of SSc in our center. Patients and methods We retrospectively evaluated medical records of all patients with SSc who used RTX to treat this disease from January 2009 to January 2015. Systemic, cutaneous, and pulmonary involvement data and laboratory results before and six months after the first infusion of RTX were collected. Results Ten patients received treatment during the study period and were included in this series. All patients had a diffuse form of the disease. Five patients suffered from an early (dura...
Source: Revista Brasileira de Reumatologia - July 23, 2016 Category: Rheumatology Source Type: research
Intestinal parasites infection: protective effect in rheumatoid arthritis?
Publication date: Available online 22 July 2016 Source:Revista Brasileira de Reumatologia (English Edition) Author(s): Sandra Maximiano de Oliveira, Ana Paula Monteiro Gomides, Lícia Maria Henrique da Mota, Caliandra Maria Bezerra Luna Lima, Francisco Airton Castro Rocha Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disease, with a progressive course, characterized by chronic synovitis that may evolve with deformities and functional disability, and whose early treatment minimizes joint damage. Its etiopathogenesis is not fully elucidated but comprises immunologic responses mediated by T hel...
Source: Revista Brasileira de Reumatologia - July 23, 2016 Category: Rheumatology Source Type: research
Unbalanced expression of aryl hydrocarbon receptor in peripheral blood CCR6+CD4+ and CD4+CD25+T cells of rheumatoid arthritis
Conclusion AhR may participate in the pathological progress of RA by controlling the differentiation of Th17 and Treg cells in peripheral blood. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - July 23, 2016 Category: Rheumatology Source Type: research
Methylene tetrahydrofolate reductase, transforming growth factor- β1 and lymphotoxin-α genes polymorphisms and susceptibility to rheumatoid arthritis
Conclusion Our findings suggest that there is association between MTHFR C677T and LT-α A252G genes polymorphisms and increased risk of RA in this sample of Egyptian population. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - July 20, 2016 Category: Rheumatology Source Type: research
