Recent Patents on Drug Delivery and Formulation 
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ANTIMICROBIAL EFFICACY OF EXTEMPORANEOUSLY PREPARED HERBAL MOUTHWASHES.
Recent Pat Drug Deliv Formul. 2015 Jun 7;
Authors: Dua K, Sheshala R, Al-Waeli HA, Gupta G, Chellappan DK
Abstract
Natural products like plants and its components have been in use for treatment and cure of diseases all around the globe from ancient times much before the discovery of the current modern drugs. These substances from the nature are well known to contain components which have therapeutic properties and can also behave as precursors for the synthesis of potential drugs. The beneficial results from h...
Source: Recent Patents on Drug Delivery and Formulation - June 10, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Characterization and Solubility Study of Norfloxacin-Polyethylene Glycol, Polyvinylpyrrolidone and Carbopol 974p Solid Dispersions.
Conclusion: The solid dispersion of norfloxacin with polyethylene glycol (PEG) 4000, polyvinylpyrrolidone (PVP) k30 and carbopol 974p NF (CP), lends an ample credence for better therapeutic efficacy.
PMID: 25714525 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - June 4, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Advances in Patents Related to Intrapocket Technology for the Management of Periodontitis.
Authors: Yadav SK, Khan G, Mishra B
Abstract
Increased prevalence of oral diseases such as gingivitis, periodontitis and dental caries has become major health issue worldwide. Such growing incidence of periodontitis has directly affected the development of drug delivery systems and growth of the market. Since the infections are limited to periodontal pockets or oral cavity, localized intrapocket drug delivery will be more beneficial than conventional systemic administration. Advances in intrapocket technology and innovations in the field of periodontal drug delivery led to increased patent applications. Ne...
Source: Recent Patents on Drug Delivery and Formulation - June 4, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Review of patents on microneedles application devices allowing fluid injections through the skin.
Authors: Lhernould MS, Tailler S, Deleers M, Delchambre A
Abstract
Microneedles have been developed in the past few years as a new transdermal drug delivery mean. They indeed present many advantages compared to injections using hypodermic needles (reduced contaminations and epidermic reactions risks), but mostly bring comfort and compliance to patients. Microneedles may be plain and open pathways for medications though the skin, dissolving into it, or hollow and allow fluid to actually enter the dermis or the hypodermis. This review focuses on this last type of microneedles and their problematic in terms o...
Source: Recent Patents on Drug Delivery and Formulation - June 4, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Risk Assessment of Nanoformulations.
Authors: Sharma HK
Abstract
In this era of Nanomedicine, Molecular medicine or Nanoformulations, I felt it to be worthy to raise certain issues for everyday discussion among the nanotechnologists, biologists, toxicologists and environmental scientists. The issues require involvement of all of them and relate the toxicity aspect of nanoformulations and assessment of risk-benefit ratio. The changes in surface properties due to reduction of particle size increase the possibility of alteration in binding affinities with biological macromolecules. The toxicity profile of nanoparticles is different from that of ...
Source: Recent Patents on Drug Delivery and Formulation - June 4, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Development of Drug Delivery Systems and Quality by Design.
Authors: Bruschi ML
Abstract
The concept and technology of drug delivery systems improved during the last sixty years. The controlled drug delivery field has its origin in the 1960s to 1980s, when a high number of systems and devices were developed to be administered by different routes and for numerous purposes. Active agents of natural and synthetic origin have been carried in each more specialized formulation with the aim to control the delivery, reduce the adverse effects, increasing the safety and patient compliance, and improving the therapeutic. Solid, semisolid and liquid systems have been develope...
Source: Recent Patents on Drug Delivery and Formulation - June 4, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Nanospray drying technology: Existing limitations and future challenges.
Authors: Wui WT
Abstract
Nanotechnology receives a widespread application in semiconductor, manufacturing, and biotechnology industries [1]. Its biggest societal impact in pharmaceutical application is related to its use in design of nanomedicine with the aim to improve medical efficacy via resolving the poor drug bioavailability status. Pharmaceutical nanoparticles can be described as solid colloidal particles with sizes below 1000 nm [1-6]. Examples of nanocarrier are liposome, cocheates, polymeric micelle, dendrimer, nanosuspension, nanoemulsion, nanosphere and nanotube [4, 7-10]. The nanoparticles can ...
Source: Recent Patents on Drug Delivery and Formulation - June 4, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Fast Dissolving/Disintegrating Dosage Forms: Growth from Immediate Release to Sustained Release and Traditional Medicines.
Authors: Saharan VA, Singh A
Abstract
Fast Dissolving/Disintegrating Dosage Forms (FDDFs) are formulated and developed for immediate drug delivery, quicker onset of action, and/or as age appropriate dosage forms meant for special populations like paediatrics, , psychotic, dysphagic, and frequent traveller patients. FDDFs family include tablets (FDTs), oral films (FDOF), mini tablets, capsules, pellets, granules etc. FDDFs dissolve/disintegrate quickly in saliva resulting in solution/suspension for oral ingestion and thereby eliminate the need for water for swallowing the dosage form.FDTs market, in regions...
Source: Recent Patents on Drug Delivery and Formulation - June 4, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Anti-cancer products from marine sponges: Progress and promise.
Authors: Shakeri A, Sahebkar A
Abstract
The marine environment covers more than 70% of the planet's surface, and its organisms are rich sources of bioactive compounds with potent pharmacological effects. Among all marine organisms investigated to date, sponges (phylum Porifera) have emerged as a valuable source for discovering cytotoxic and anti-cancer drugs owing to their diverse content of secondary metabolites with various chemical structures. Hitherto, around 15,000 sponges have been identified and more than 5,000 different compounds have been isolated and structurally characterized, contributing to ab...
Source: Recent Patents on Drug Delivery and Formulation - June 4, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
