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Development of Floating Delivery for Solid Self Micro-Emulsifying Drug Delivery System of Prochlorperazine Maleate.
Conclusion It can be concluded that SMEDD enhanced the solubility of drug and floating capsule gave site specific drug release of PCM with the advantages of reduced dosing frequency and better compliance. PMID: 29119940 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - November 11, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Recent Patent Advances For Neurodegenerative Disorders And Its Treatment.
CONCLUSION: The review will attract the interest of academics, researchers, students and pharmaceutical companies in the recent on-going activities in neurodegenerative disorders. PMID: 29032765 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - October 18, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

A Review of Patents on Therapeutic Potential and Delivery of Hydrogen Sulfide.
Authors: Verma R, Akhtar Y, Singh S Abstract Hydrogen sulfide (H2S) is a colorless gas with a characteristic smell of rotten eggs. Once only thought of as a toxic gas, evidence now shows that H2S plays major roles in pathological and physiological activities. These roles are being utilized to treat diseases and disorders ranging from hypertension, inflammation, edema, cardiovascular issues, chronic pain, cancer, and many more. Challenges facing the use of H2S currently involve achieving the optimum therapeutic concentrations, synthesizing chemically and physiologically stable donors, and developing clinica...
Source: Recent Patents on Drug Delivery and Formulation - September 15, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Editorial.
Authors: Donnelly RF PMID: 28877660 [PubMed - in process] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - September 8, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Formulation, Characterization and In-Vitro Evaluation of Fast Dissolving Tablets Containing Gliclazide Hydrotropic Solid Dispersions.
CONCLUSION: It was concluded that the enhancement in solubility of GLZ is clear indication of the potential of mixed hydrotropy which is a novel, safe and cost-effective technique to be employed for other poorly water-soluble drugs having low bioavailability. PMID: 28460615 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - May 5, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Bronchoscopy in children for research with questionable indications: an overview of Russian patents and publications.
Authors: Jargin SV Abstract This letter is a continuation of preceding reviews on invasive methods applied with questionable clinical indications and/or research purposes. It aims to serve as a reminder that the risk-to-benefit ratio should be kept as low as possible. The use of bronchoscopy for diagnostics and treatment of asthma and bronchitis in children is discussed in more detail. Various bronchoscopic methods applied in children and adults have been patented; several patents are presented here as examples. The concept of informed consent and assent applied to children and adolescents is also discusse...
Source: Recent Patents on Drug Delivery and Formulation - May 5, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Environmentally responsive systems for drug delivery.
CONCLUSION: Therefore, in this review, since 1975 to 2016, we have categorized, reviewed and discussed the patents, applications, pharmaceutical dosage forms, the importance and perspectives of this environmentally responsive approach as potentially useful therapeutic modality. PMID: 28355996 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - April 1, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Magnetic nanoparticles: A review on stratagems of fabrication and its biomedical applications.
Authors: Srivastava P, Sharma PK, Muheem A, Warsi MH Abstract The aim of this review is to provide an insight to the underlying biomedical applications of magnetic nanoparticles (MNPs).. The most specific characteristic of MNPs is their response to an applied magnetic force, and this property of MNPs has been utilized in applications such as diagnosis of diseases, drug delivery and drug targeting. Currently, MNPs have attracted great attention because of their potential as contrast agents for magnetic resonance imaging (MRI) and heat mediators for cancer therapy (hyperthermia). Furthermore, the MNPs are al...
Source: Recent Patents on Drug Delivery and Formulation - April 1, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Probiotics as a Tool to Biosynthesize Metallic Nanoparticles: Research Reports and Patents Survey.
CONCLUSION: Use of probiotic bacteria in synthesizing metallic nanoparticles is an effective biosynthetic approach. However, the technique needs wider exploration for newer metallic/nonmetallic/metalloid NPs for therapeutic applications. PMID: 28294074 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - March 17, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Development and Characterization Pulsatile Microspheres of Nifedipine for Hypertension.
CONCLUSION: On the basis of data formulation F83 showed slow release and at a particular lag time followed pulsatile release pattern and followed first order kinetics model. It was concluded that the formulated nifedipine pulsatile dosage form could be useful in the treatment of hypertension. PMID: 28201961 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - February 18, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Preparation and Optimization of Fast Dissolving Film of Naratriptan Hydrochloride.
Authors: Koradia KD, Sidhdhapara PT, Sheth NR Abstract BACKGROUND AND OBJECTIVE: Naratriptan is second-generation triptan class of antimigraine drug which selectively bind with 5-HT(1B/1D) receptor. It is widely used to treat the migraine attack due to its better tolerability and lower recurrence rate as compared to other triptans. Despite of the applicability, Naratriptan also have several drawback like slow onset of action and fist pass metabolism which reduce its efficacy. In order to increase the efficacy of naratriptan fast dissolving film is prepared. METHOD: Fast dissolving film of Naratript...
Source: Recent Patents on Drug Delivery and Formulation - February 18, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Acyclovir Solid lipid nanoparticles for skin drug delivery: Fabrication, Characterization and In vitro study.
Conclusion: SLN dispersions exhibited the average size in nano range. SLNs with small particle size found to have predetermined encapsulation efficiency and relatively high loading capacity and predetermined in vitro drug release profile. The lipoid S and Pluronic F68 nanoparticles are found to be superior to Conventional GMS and tween 80 nanoparticles in terms of particles size, stability and zeta potential. PMID: 28124592 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - January 27, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Formulation Development And Evaluation Of Lyophilized Nasal Inserts For Migraine Treatment.
CONCLUSION: The best nasal inserts formulation containing chitosan and xanthan gum in the ratio 0.5:0.5, showed desirable % drug release as well as bioadhesion which may result in an increase in the nasal residence time. Keyword: Polyelectrolyte complexes; Lyophilized bioadhesive inserts; Rizatriptan benzoate; Nasal delivery, Natural polymer, Polycation/Polyanion. PMID: 28103774 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - January 21, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Formulation and optimization of Lansoprazole pellets using factorial design prepared by extrusion-spheronization technique using Carboxymethyl tamarind kernel powder.
CONCLUSION: Drug release of the optimized batch (2F7) and marketed formulation (LANZOL cap) was found to be 82.33 % and 80.07 % respectively. An accelerated study indicated that optimized formulation was stable. PMID: 28088896 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - January 17, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Development and evaluation of naproxen sodium gel using Piper cubeba for enhanced transdermal drug delivery and therapeutic facilitation.
CONCLUSION: It suggests P. cubeba as effective and safer tool for transdermal delivery and acts as therapeutic facilitator for naproxen. GC-MS analysis indicates lignans amp; terpenes in NHE to which this permeation enhancement activity may be attributed. PMID: 28056749 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - January 7, 2017 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research