Recent Patents on Drug Delivery and Formulation 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.The protective action of the aqueous extract of auricularia polytricha in paracetamol induced hepatotoxicity in rats.
THE PROTECTIVE ACTION OF THE AQUEOUS EXTRACT OF AURICULARIA POLYTRICHA IN PARACETAMOL INDUCED HEPATOTOXICITY IN RATS.
Recent Pat Drug Deliv Formul. 2015 Oct 30;
Authors: Chellappan DK, Ganasen S, Batumalai S, Candasamy M, Krishnappa P, Dua K, Chellian J, Gupta G
Abstract
Natural antioxidant products are increasingly being used to treat various pathological liver injuries considering the role of oxidative stress in their pathogenesis. Auricularia polytricha been put to use as food or medicine due to its antioxidant activity. The aim of the study was to evaluate the protective effec...
Source: Recent Patents on Drug Delivery and Formulation - November 1, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Liposheres as a novel carrier for lipid based drug delivery: current and future directions.
LIPOSHERES AS A NOVEL CARRIER FOR LIPID BASED DRUG DELIVERY: CURRENT AND FUTURE DIRECTIONS.
Recent Pat Drug Deliv Formul. 2015 Oct 1;
Authors: Swain S, Beg S, Babu SM
Abstract
Researchers are facing challenges to develop and enhance the bioavailability of poorly water-soluble drugs towards clinical applications. The development of new drug molecule alone is not adequate to assure ample pharmacotherapy of various diseases. Considerable results obtained from in vitro studies are not supported with in vivo data due to inadequate plasma drug concentrations. This may occur due to limit...
Source: Recent Patents on Drug Delivery and Formulation - October 3, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
The Sojourn from Parenteral to Oral Taxanes using Nanocarrier Systems: A Patent Review.
Authors: Khurana RK, Teenu, Mahajan M, Kapoor S, Jain S, Singh B
Abstract
Natural diterpenoid taxanes and their semisynthetic analogues have already made an indelible mark in the chemotherapeutic world for treating various kinds of malignancies. However, due to the absence of any functional groups which could be ionized by pH alteration or which may participate in salt formation, these taxanes, exhibit low solubility. Parenteral administration of taxanes with solubilising agents such as Cremophor EL and Polysorbate 80 results in undesirable side effects like hypersensitivity reactions, myelosuppression and...
Source: Recent Patents on Drug Delivery and Formulation - October 3, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Investigative approaches for oral delivery of anticancer drugs: A patent review.
This article explores the encouraging reports, recent patents and inventions on the feasibility and applicability of oral administration of chemotherapeutics.
PMID: 26310247 [PubMed - as supplied by publisher] (Source: Recent Patents on Drug Delivery and Formulation)
Source: Recent Patents on Drug Delivery and Formulation - August 29, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Recent patents on nanoparticles and nanoformulations for cancer therapy.
Authors: Ray A, Mandal A, Joseph M, Mitra AK
Abstract
Cancer is a major malignancy which has claimed numerous lives worldwide. Despite huge resources being utilized to develop cancer therapeutics, no effective cure has been found so far. Hence there is a need to look at emerging technologies for a solution. Nanoparticle is one such technology that have become feasible and popular in the past few years. Though, it has not emerged as a drug delivery platform of choice for cancer therapeutics it has shown enormous promise. Different types of materials such as polymer, lipid, magnet, metal based nanoparticles ...
Source: Recent Patents on Drug Delivery and Formulation - August 19, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Phytosome: A Fatty Solution for Efficient Formulation of Phytopharmaceuticals.
Authors: Shakeri A, Sahebkar A
Abstract
During the past two decades, it has become well-known that phytomedicines could be successfully employed to treat several types of human diseases.However, low systemic bioavailability is commonly referred to as a major obstacle to achieve the maximum efficacy of phytomedicines in clinical practice. This low bioavailability is mainly due to either highly polar and water soluble, or strong lipophilic natureof some phytochemicals, causing hydrophilic lipophilic balance values that hinder complete passage of phytochemical through either unstirred water layer covering bru...
Source: Recent Patents on Drug Delivery and Formulation - August 14, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Recent patents in pulmonary delivery of macromolecules.
This article reviews the advances in pulmonary drug delivery systems by focusing on the recent patents in delivery of macromolecules. Furthermore, recent patents in gene delivery to the lungs have also been discussed. List of patents included in this review is comprehensive in terms of pulmonary delivery of therapeutics. It includes inventions related to proteins and peptides, DNA therapeutics, siRNA and other genetic materials with therapeutic applications. The diseases targeted by these therapeutic molecules are varied including but not limited to different forms of cancer, respiratory diseases etc.
PMID: 2621993...
Source: Recent Patents on Drug Delivery and Formulation - July 31, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Applicability, Commercial Utility and Recent Patents on Starch and Starch Derivative as Pharmaceutical Drug Delivery Carrier.
This article summarizes the starch and modification of starch and to produce a novel molecule with various applications in industries including a many number of advances in pharmaceutical industry. The unique characteristics of starch and their modified form can be successfully used as drug delivery carriers in various pharmaceutical preparations. It is widely used as controlled and sustained release polymer, tablet disintegrant, drug delivery carrier, plasma volume expander and also finds its applicability in bone tissue engineering and in artificial red cells. It also includes the patents related to starch and modified s...
Source: Recent Patents on Drug Delivery and Formulation - July 26, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
In Situ Gelling Ophthalmic Drug Delivery System: An Overview and Its Applications.
Authors: Sheshala R, Kok YY, Ng JM, Thakur RR, Dua K
Abstract
Ophthalmic drug delivery system is very interesting and challenging due to the normal physiologically factor of eyes which reduces the bioavailability of ocular products. The development of a new ophthalmic dosage forms with the existing drugs to improve efficacy and bioavailability including better patients' compliance and convenience has become trend in the most pharmaceutical industries. The present review encompasses various conventional and novel ocular drug delivery systems, methods of preparation, characterization, recent researches carri...
Source: Recent Patents on Drug Delivery and Formulation - July 26, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Recent patents, formulation and characterization of nanoliposomes.
RECENT PATENTS, FORMULATION AND CHARACTERIZATION OF NANOLIPOSOMES.
Recent Pat Drug Deliv Formul. 2015 Jun 28;
Authors: Dureja H, Rohilla S
Abstract
Nanoliposome has been introduced for nanoscale bilayer lipid vesicles. These are the nano version of liposomes, having cell-specific targeting, required to achieve a desired drug concentration at the target site for optimum therapeutic efficacy, possibly by minimizing the adverse effects on healthy cells and tissues. Nanoliposomes possess impending applications in the fields of nanotechnology, e.g. cancer therapy, cosmetics, diagnosis,...
Source: Recent Patents on Drug Delivery and Formulation - July 1, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Telomere Attrition in Human Lens Epithelial Cells Associated with Oxidative Stress Provide a New Therapeutic Target for the Treatment, Dissolving and Prevention of Cataract with N-Acetylcarnosine Lubricant Eye Drops. Kinetic, Pharmacological and Activity-Dependent Separation of Therapeutic Targeting: Transcorneal Penetration and Delivery of L-Carnosine in the Aqueous Humor and Hormone-Like Hypothalamic Antiaging Effects of the Instilled Ophthalmic Drug Through a Safe Eye Medication Technique.
In this study we aimed to be focused on research defining the mechanisms that underlie linkages among telomere attrition in human lens epithelial cells associated with oxidative stress, biology of the lens response to oxidative damages, aging and health, cataract versus neuroendocrine regulation and disease. The cumulative results demonstrate that carnosine, released ophthalmically from the patented 1% N-acetylcarnosine prodrug lubricant eye drops, at physiological concentration might remarkably reduce the rate of telomere shortening in the lens cells subjected to oxidative stress in the lack of efficient antioxidant lens ...
Source: Recent Patents on Drug Delivery and Formulation - June 20, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Bilosomes: A novel approach to meet the challenges in oral immunization.
Authors: Chauhan MK, Sahoo PK, Rawat AS, Singh A, Bamrara A, Sharma D
Abstract
Oral immunization with vaccines has proven its worth by eradicating several diseases worldwide, yet only few oral vaccines exist in practice. This is because the oral route is plagued with various challenges for successful delivery of vaccines, such as limited absorption and high degradation in gastrointestinal tract. Tremendous research in the last decade has made bilosomes a potential carrier system for oral immunization. Bilosomes with its name derived from bile salts, one of its major constituent, is a 'niosome-like' colloid...
Source: Recent Patents on Drug Delivery and Formulation - June 16, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Modular drug delivery systems for personalized oral dosage forms.
Authors: Colombo P
Abstract
A drug delivery platform based on a modular dosage forms have been developed at University of Parma (1). Release modules consisted in cylindrical tablets or matrices, having a concave and a convex base to be assembled by friction interlocking in a firm drug delivery system. The interlocking was obtained by forcing the convex base of one module into the concavity of another one. Modules have been constructed with several different matrix materials and compositions (2-3). The typical diameter of the module was 7.4 mm and the number of modules assembled was six in case of high dose...
Source: Recent Patents on Drug Delivery and Formulation - June 14, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Nanotechnology: A Successful Approach to Improve Oral Bioavailability of Phytochemicals.
Authors: Shakeri A, Sahebkar A
Abstract
Phytochemicals have gained significant recognition for their potential therapeutic uses against a variety of human diseases. However, the poor water solubility, limited intestinal absorption and low water stability of phytochemicals generally prevent from achieving a high oral bioavailability and even detectable plasma levels of the parent compound. Dose escalation is not always a solution to address limited oral bioavailability, and may increase the risk of adverse events, most frequently in the gastrointestinal system [1]. Low water solubility is a common reason fo...
Source: Recent Patents on Drug Delivery and Formulation - June 14, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
3d printing in drug delivery formulation: you can dream it, design it and print it. how about patent it?
3D PRINTING IN DRUG DELIVERY FORMULATION: YOU CAN DREAM IT, DESIGN IT AND PRINT IT. HOW ABOUT PATENT IT?
Recent Pat Drug Deliv Formul. 2015 Jun 7;
Authors: Pillay V, Choonara YE
Abstract
3D Printing (3DP) is a rapidly evolving interdisciplinary technology based on the manipulation of human thought into tangible products. The concept of 3DP enables inventive scientists to translate a realm of dreamful concepts to actual lab prototypes. When 3DP was first introduced a while back it was clear to many forward thinking pharmaceutical formulation scientists that it would soon become the...
Source: Recent Patents on Drug Delivery and Formulation - June 10, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
