Liposheres as a novel carrier for lipid based drug delivery: current and future directions.

LIPOSHERES AS A NOVEL CARRIER FOR LIPID BASED DRUG DELIVERY: CURRENT AND FUTURE DIRECTIONS. Recent Pat Drug Deliv Formul. 2015 Oct 1; Authors: Swain S, Beg S, Babu SM Abstract Researchers are facing challenges to develop and enhance the bioavailability of poorly water-soluble drugs towards clinical applications. The development of new drug molecule alone is not adequate to assure ample pharmacotherapy of various diseases. Considerable results obtained from in vitro studies are not supported with in vivo data due to inadequate plasma drug concentrations. This may occur due to limited solubility and absorption. To resolve these problems, development of new drug delivery systems will be a promising approach. One of the promising pharmaceutical strategies is the use of lipospheres drug delivery system to deliver the poorly water-soluble drugs. Therefore, the present review described about methodology for manufacturing of lipospheres, factors influencing the formulation to deliver the drugs in the targeted site. Apart from that this review also enlisted briefly about the various applications of liposphers in medical and biomedical fields. PMID: 26423443 [PubMed - as supplied by publisher]
Source: Recent Patents on Drug Delivery and Formulation - Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research