Formulation Development And Evaluation Of Lyophilized Nasal Inserts For Migraine Treatment.

CONCLUSION: The best nasal inserts formulation containing chitosan and xanthan gum in the ratio 0.5:0.5, showed desirable % drug release as well as bioadhesion which may result in an increase in the nasal residence time. Keyword: Polyelectrolyte complexes; Lyophilized bioadhesive inserts; Rizatriptan benzoate; Nasal delivery, Natural polymer, Polycation/Polyanion. PMID: 28103774 [PubMed - as supplied by publisher]
Source: Recent Patents on Drug Delivery and Formulation - Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research