Advances in Patents Related to Intrapocket Technology for the Management of Periodontitis.

Advances in Patents Related to Intrapocket Technology for the Management of Periodontitis.
Recent Pat Drug Deliv Formul. 2015 Mar 10;
Authors: Yadav SK, Khan G, Mishra B
Abstract
Increased prevalence of oral diseases such as gingivitis, periodontitis and dental caries has become major health issue worldwide. Such growing incidence of periodontitis has directly affected the development of drug delivery systems and growth of the market. Since the infections are limited to periodontal pockets or oral cavity, localized intrapocket drug delivery will be more beneficial than conventional systemic administration. Advances in intrapocket technology and innovations in the field of periodontal drug delivery led to increased patent applications. Newer trends like use of mucoadhesive polymers, in situ forming gels, viscosity modifiers, plasticizers etc which can enhance intrapocket retention of drugs have gained considerable attention among researchers and industrialists. Current market is flooded with products such as Periostat, Periochip®, Atridox®, Arestin®, Actisite®, Dentomycin®, and Elyzol® and generics such as metronidazole, levofloxacin, tetracycline, doxycyline and minocycline for intrapocket delivery. There is a need of novel drugs and delivery systems with better efficacy profiles than the existing compounds. Inclusion of novel technologies like films, fibers, in situ forming implants, microparticles, nanoparticles, and liposome...

Source: Recent Patents on Drug Delivery and Formulation - June 4, 2015 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research