Fast Dissolving/Disintegrating Dosage Forms: Growth from Immediate Release to Sustained Release and Traditional Medicines.

Fast Dissolving/Disintegrating Dosage Forms: Growth from Immediate Release to Sustained Release and Traditional Medicines. Recent Pat Drug Deliv Formul. 2015 May 29; Authors: Saharan VA, Singh A Abstract Fast Dissolving/Disintegrating Dosage Forms (FDDFs) are formulated and developed for immediate drug delivery, quicker onset of action, and/or as age appropriate dosage forms meant for special populations like paediatrics, , psychotic, dysphagic, and frequent traveller patients. FDDFs family include tablets (FDTs), oral films (FDOF), mini tablets, capsules, pellets, granules etc. FDDFs dissolve/disintegrate quickly in saliva resulting in solution/suspension for oral ingestion and thereby eliminate the need for water for swallowing the dosage form.FDTs market, in regions of US, Europe, and Japan, grew more than $8.4 billion in 2011 and is expected to reach to $12 billion globally by 2018[1]. FDOF market is expected to attain $1 billion mark in 2015 [1]. FDDFs have successfully entered in Pharmacopoeia as Orally Disintegrating Tablets (US and Japan) or Orodispersible Tablets (ODT or OD Tablet) [Europe and Japan] and orodispersible films (ODF) [Europe].FDDFs have recently shifted their focus beyond immediate release FDDFs to controlled/sustained release FDDFs forphytopharmaceuticals and traditional medicines. Quicker dissolution/disintegration of FDDFs and use of low compression forces or methods of shaping tablets/dosage forms without c...
Source: Recent Patents on Drug Delivery and Formulation - Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research