Pain: A painful loss of inhibition
Nature Reviews Neuroscience 18, 456 (2017).
doi:10.1038/nrn.2017.88
Author: Natasha Bray
The development of chronic neuropathic pain is associated with cortical hyperexcitability and a marked decrease in inhibition, particularly from cortical somatostatin-expressing interneurons. (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - July 13, 2017 Category: Neuroscience Authors: Natasha Bray Tags: Research Highlight Source Type: research
Gut-brain communication: Making contact
Nature Reviews Neuroscience 18, 452 (2017).
doi:10.1038/nrn.2017.89
Author: Katherine Whalley
Enterochromaffin cells in the gut epithelium act as chemosensors and can modulate neural function in response to intestinal signals. (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - July 13, 2017 Category: Neuroscience Authors: Katherine Whalley Tags: Research Highlight Source Type: research
A new look at domain specificity: insights from social neuroscience
Nature Reviews Neuroscience 18, 559 (2017).
doi:10.1038/nrn.2017.76
Authors: Robert P. Spunt & Ralph Adolphs
The concept of domain specificity — which suggests that some aspects of neural processing are specialized for particular types of stimuli — has been invoked to explain a range of cognitive phenomena, including language, face perception and theory of mind, and has been a hallmark (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - July 6, 2017 Category: Neuroscience Authors: Robert P. Spunt Ralph Adolphs Tags: Perspectives Source Type: research
Cancer: Appetite suppressors
Nature Reviews Neuroscience 18, 457 (2017).
doi:10.1038/nrn.2017.86
Author: Darran Yates
Calcitonin gene-related peptide-expressing neurons in the external parabrachial nucleus can drive cancer-induced anorexia in mice. (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - July 6, 2017 Category: Neuroscience Authors: Darran Yates Tags: Research Highlight Source Type: research
Psychiatric disorders: A sensitive window
Nature Reviews Neuroscience 18, 453 (2017).
doi:10.1038/nrn.2017.84
Author: Natasha Bray
In mice, postnatal stress leads to long-lasting changes in transcription in the ventral tegmental area, sensitizing the brain to stress later in life. (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - July 6, 2017 Category: Neuroscience Authors: Natasha Bray Tags: Research Highlight Source Type: research
Neuroimmunology: Mistaken identity
Nature Reviews Neuroscience 18, 452 (2017).
doi:10.1038/nrn.2017.87
Author: Sian Lewis
Fragments of the protein α-synuclein, which accumulates in substantia nigra neurons in Parkinson disease, are expressed on the surface of these substantia nigra neurons and induce a form of autoimmunity that could account for the degeneration of these cells in the disease. (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - July 6, 2017 Category: Neuroscience Authors: Sian Lewis Tags: Research Highlight Source Type: research
Prefrontal – hippocampal interactions in episodic memory
Nature Reviews Neuroscience 18, 547 (2017).
doi:10.1038/nrn.2017.74
Author: Howard Eichenbaum
The roles of the hippocampus and prefrontal cortex (PFC) in memory processing — individually or in concert — are a major topic of interest in memory research. These brain areas have distinct and complementary roles in episodic memory, and their interactions are crucial for learning (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - June 29, 2017 Category: Neuroscience Authors: Howard Eichenbaum Tags: Review Source Type: research
Mammalian empathy: behavioural manifestations and neural basis
Nature Reviews Neuroscience 18, 498 (2017).
doi:10.1038/nrn.2017.72
Authors: Frans B. M. de Waal & Stephanie D. Preston
Recent research on empathy in humans and other mammals seeks to dissociate emotional and cognitive empathy. These forms, however, remain interconnected in evolution, across species and at the level of neural mechanisms. New data have facilitated the development of empathy models such as the perception–action (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - June 29, 2017 Category: Neuroscience Authors: Frans B. M. de Waal Stephanie D. Preston Tags: Review Source Type: research
Taste buds: cells, signals and synapses
Nature Reviews Neuroscience 18, 485 (2017).
doi:10.1038/nrn.2017.68
Authors: Stephen D. Roper & Nirupa Chaudhari
The past decade has witnessed a consolidation and refinement of the extraordinary progress made in taste research. This Review describes recent advances in our understanding of taste receptors, taste buds, and the connections between taste buds and sensory afferent fibres. The article discusses new findings (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - June 29, 2017 Category: Neuroscience Authors: Stephen D. Roper Nirupa Chaudhari Tags: Review Source Type: research
Microglia: A protective population?
Nature Reviews Neuroscience 18, 454 (2017).
doi:10.1038/nrn.2017.83
Author: Katherine Whalley
Disease progression in a mouse model of Alzheimer disease is associated with the appearance of a population of disease-associated microglia that can phagocytose amyloid-β. (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - June 29, 2017 Category: Neuroscience Authors: Katherine Whalley Tags: Research Highlight Source Type: research
Sensory systems: Tasting the water
Nature Reviews Neuroscience 18, 454 (2017).
doi:10.1038/nrn.2017.82
Author: Sian Lewis
Water in the external environment is detected by acid-sensing taste receptor cells via a carbonic anhydrase 4-mediated pH change. (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - June 29, 2017 Category: Neuroscience Authors: Sian Lewis Tags: Research Highlight Source Type: research
Neuroimmunology and neuroepigenetics in the establishment of sex differences in the brain
Nature Reviews Neuroscience 18, 471 (2017).
doi:10.1038/nrn.2017.61
Authors: Margaret M. McCarthy, Bridget M. Nugent & Kathryn M. Lenz
The study of sex differences in the brain is a topic of neuroscientific study that has broad reaching implications for culture, society and biomedical science. Recent research in rodent models has led to dramatic shifts in our views of the mechanisms underlying the sexual differentiation (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - June 22, 2017 Category: Neuroscience Authors: Margaret M. McCarthy Bridget M. Nugent Kathryn M. Lenz Tags: Review Source Type: research
Neural circuits underlying thirst and fluid homeostasis
Nature Reviews Neuroscience 18, 459 (2017).
doi:10.1038/nrn.2017.71
Authors: Christopher A. Zimmerman, David E. Leib & Zachary A. Knight
Thirst motivates animals to find and consume water. More than 40 years ago, a set of interconnected brain structures known as the lamina terminalis was shown to govern thirst. However, owing to the anatomical complexity of these brain regions, the structure and dynamics of their (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - June 22, 2017 Category: Neuroscience Authors: Christopher A. Zimmerman David E. Leib Zachary A. Knight Tags: Progress Source Type: research
Neural coding: Face values
Nature Reviews Neuroscience 18, 456 (2017).
doi:10.1038/nrn.2017.81
Author: Natasha Bray
Neurons in the 'face patch' system in macaques code features of realistic faces along various continuous axes. (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - June 22, 2017 Category: Neuroscience Authors: Natasha Bray Tags: Research Highlight Source Type: research
Linking social context and addiction neuroscience: a computational psychiatry approach
Nature Reviews Neuroscience 18, 450 (2017).
doi:10.1038/nrn.2017.67
Authors: Andrea Reiter, Andreas Heinz & Lorenz Deserno
In their recent article (Time to connect: bringing social context into addiction neuroscience (Nat. Rev. Neurosci.17, 592–599 (2016)), Heilig et al. suggest that the lack of progress towards treatment and prevention of addiction is partly due to a neglect (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - June 19, 2017 Category: Neuroscience Authors: Andrea Reiter Andreas Heinz Lorenz Deserno Tags: Correspondence Source Type: research
