Epigenetic orchestration of thymic Treg cell development
Nature Immunology 18, 144 (2017).
doi:10.1038/ni.3660
Authors: Marc Beyer & Jochen Huehn
Regulatory T cells develop in the thymus as a distinct lineage of T cells instructed by the lineage-specifying transcription factor Foxp3. Epigenetic imprinting by the genome organizer Satb1 precedes this cell-fate 'decision' during thymocyte development. (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Marc Beyer Jochen Huehn Tags: News and Views Source Type: research
Is sex bias orchestrated in the skin?
Nature Immunology 18, 142 (2017).
doi:10.1038/ni.3658
Authors: Aridaman Pandit, Linde Meyaard & Timothy R D J Radstake
The identification of VGLL3 as a transcription (co-)factor that underlies the sex bias of the human immune system further underscores the relevance of research into this area. (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Aridaman Pandit Linde Meyaard Timothy R D J Radstake Tags: News and Views Source Type: research
Direct control of regulatory T cells by keratinocytes
Nature Immunology 18, 334 (2017).
doi:10.1038/ni.3661
Authors: Mariko Kashiwagi, Junichi Hosoi, Jen-Feng Lai, Janice Brissette, Steven F Ziegler, Bruce A Morgan & Katia Georgopoulos (Source: Nature Immunology)
Source: Nature Immunology - January 15, 2017 Category: Allergy & Immunology Authors: Mariko Kashiwagi Junichi Hosoi Jen-Feng Lai Janice Brissette Steven F Ziegler Bruce A Morgan Katia Georgopoulos Tags: Article Source Type: research
Infectious immunity in the central nervous system and brain function
Nature Immunology 18, 132 (2017).
doi:10.1038/ni.3656
Authors: Robyn S Klein, Charise Garber & Nicole Howard (Source: Nature Immunology)
Source: Nature Immunology - January 15, 2017 Category: Allergy & Immunology Authors: Robyn S Klein Charise Garber Nicole Howard Tags: Review Source Type: research
The movers and shapers in immune privilege of the CNS
Nature Immunology 18, 123 (2017).
doi:10.1038/ni.3666
Authors: Britta Engelhardt, Peter Vajkoczy & Roy O Weller (Source: Nature Immunology)
Source: Nature Immunology - January 15, 2017 Category: Allergy & Immunology Authors: Britta Engelhardt Peter Vajkoczy Roy O Weller Tags: Review Source Type: research
Neuroimmune regulation during intestinal development and homeostasis
Nature Immunology 18, 116 (2017).
doi:10.1038/ni.3634
Authors: Henrique Veiga-Fernandes & Vassilis Pachnis (Source: Nature Immunology)
Source: Nature Immunology - January 15, 2017 Category: Allergy & Immunology Authors: Henrique Veiga-Fernandes Vassilis Pachnis Tags: Review Source Type: research
Neuroimmune communication
We present a special set of Review articles on neuroimmune communication that highlight how the immune system and nervous system are anatomically connected, mechanistically communicate and reciprocally influence the other's function. (Source: Nature Immunology)
Source: Nature Immunology - January 15, 2017 Category: Allergy & Immunology Tags: Editorial Source Type: research
HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3
Nature Immunology 18, 225 (2017).
doi:10.1038/ni.3647
Authors: Sonja I Gringhuis, Nina Hertoghs, Tanja M Kaptein, Esther M Zijlstra-Willems, Ramin Sarrami-Fooroshani, Joris K Sprokholt, Nienke H van Teijlingen, Neeltje A Kootstra, Thijs Booiman, Karel A van Dort, Carla M S Ribeiro, Agata Drewniak & Teunis B H Geijtenbeek (Source: Nature Immunology)
Source: Nature Immunology - December 25, 2016 Category: Allergy & Immunology Authors: Sonja I Gringhuis Nina Hertoghs Tanja M Kaptein Esther M Zijlstra-Willems Ramin Sarrami-Fooroshani Joris K Sprokholt Nienke H van Teijlingen Neeltje A Kootstra Thijs Booiman Karel A van Dort Carla M S Ribeiro Agata Drewniak Teunis B H Geijtenbeek Tags: Article Source Type: research
The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination
Nature Immunology 18, 214 (2017).
doi:10.1038/ni.3641
Authors: Bingyu Liu, Meng Zhang, Honglei Chu, Honghai Zhang, Haifeng Wu, Guanhua Song, Peng Wang, Kai Zhao, Jinxiu Hou, Xueer Wang, Lei Zhang & Chengjiang Gao (Source: Nature Immunology)
Source: Nature Immunology - December 18, 2016 Category: Allergy & Immunology Authors: Bingyu Liu Meng Zhang Honglei Chu Honghai Zhang Haifeng Wu Guanhua Song Peng Wang Kai Zhao Jinxiu Hou Xueer Wang Lei Zhang Chengjiang Gao Tags: Article Source Type: research
The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells
Nature Immunology 18, 184 (2017).
doi:10.1038/ni.3644
Authors: Semir Beyaz, Ji Hyung Kim, Luca Pinello, Michael E Xifaras, Yu Hu, Jialiang Huang, Marc A Kerenyi, Partha P Das, R Anthony Barnitz, Aurelie Herault, Rizkullah Dogum, W Nicholas Haining, Ömer H Yilmaz, Emmanuelle Passegue, Guo-Cheng Yuan, Stuart H Orkin & Florian Winau (Source: Nature Immunology)
Source: Nature Immunology - December 18, 2016 Category: Allergy & Immunology Authors: Semir Beyaz Ji Hyung Kim Luca Pinello Michael E Xifaras Yu Hu Jialiang Huang Marc A Kerenyi Partha P Das R Anthony Barnitz Aurelie Herault Rizkullah Dogum W Nicholas Haining Ömer H Yilmaz Emmanuelle Passegue Guo-Cheng Yuan Stuart H Orkin Florian Winau Tags: Article Source Type: research
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
Nature Immunology 18, 173 (2017).
doi:10.1038/ni.3646
Authors: Yohko Kitagawa, Naganari Ohkura, Yujiro Kidani, Alexis Vandenbon, Keiji Hirota, Ryoji Kawakami, Keiko Yasuda, Daisuke Motooka, Shota Nakamura, Motonari Kondo, Ichiro Taniuchi, Terumi Kohwi-Shigematsu & Shimon Sakaguchi (Source: Nature Immunology)
Source: Nature Immunology - December 18, 2016 Category: Allergy & Immunology Authors: Yohko Kitagawa Naganari Ohkura Yujiro Kidani Alexis Vandenbon Keiji Hirota Ryoji Kawakami Keiko Yasuda Daisuke Motooka Shota Nakamura Motonari Kondo Ichiro Taniuchi Terumi Kohwi-Shigematsu Shimon Sakaguchi Tags: Article Source Type: research
A gene network regulated by the transcription factor VGLL3 as a promoter of sex-biased autoimmune diseases
Nature Immunology 18, 152 (2017).
doi:10.1038/ni.3643
Authors: Yun Liang, Lam C Tsoi, Xianying Xing, Maria A Beamer, William R Swindell, Mrinal K Sarkar, Celine C Berthier, Philip E Stuart, Paul W Harms, Rajan P Nair, James T Elder, John J Voorhees, J Michelle Kahlenberg & Johann E Gudjonsson (Source: Nature Immunology)
Source: Nature Immunology - December 18, 2016 Category: Allergy & Immunology Authors: Yun Liang Lam C Tsoi Xianying Xing Maria A Beamer William R Swindell Mrinal K Sarkar Celine C Berthier Philip E Stuart Paul W Harms Rajan P Nair James T Elder John J Voorhees J Michelle Kahlenberg Johann E Gudjonsson Tags: Article Source Type: research
TSLP in bacterial skin infection
Nature Immunology 18, 14 (2017).
doi:10.1038/ni.3653
Author: Laurie A Dempsey (Source: Nature Immunology)
Source: Nature Immunology - December 15, 2016 Category: Allergy & Immunology Authors: Laurie A Dempsey Tags: Research Highlights Source Type: research
CD148 function in B-1 cells
Nature Immunology 18, 14 (2017).
doi:10.1038/ni.3652
Author: Laurie A Dempsey (Source: Nature Immunology)
Source: Nature Immunology - December 15, 2016 Category: Allergy & Immunology Authors: Laurie A Dempsey Tags: Research Highlights Source Type: research
Motile recognition
Nature Immunology 18, 14 (2017).
doi:10.1038/ni.3651
Author: Zoltan Fehervari (Source: Nature Immunology)
Source: Nature Immunology - December 15, 2016 Category: Allergy & Immunology Authors: Zoltan Fehervari Tags: Research Highlights Source Type: research
